“NMN among other compounds” in reversing cognitive impairment due to obstruction of blood flow to the brain.

NMN, Metformin, and Rapamycin Mitigate Age-Related Cognitive Impairment This study by the University of North Texas had the following findings: • Treatment with (1) NMN, (2) metformin, or (3) rapamycin improves learning and memory in rats modeling vascular cognitive impairment (VCI), the second leading cause of dementia after Alzheimer’s disease. • The compounds reduce brain lesions caused by the lack […]

What are the brain diseases that you can think of?

They include the followings which are not exhaustive: 1. Dementia & Alzheimer’s disease 2. Brain cancer 3. Parkinson disease 4. Stroke 5. Epilepsy 6. Meningitis 7. Migraine 8. Depression 9. Autism ….etc. There are many causes leading to these diseases: ♦️Cerebrovascular ♦️Infection ♦️Tumor ♦️Aging leading to brain atrophy & degeneration ♦️Others Let’s briefly look at these one by one. ♦️ […]

Compound found in red wine opens door for new treatments for depression, anxiety

Compound found in red wine opens door for new treatments for depression, anxiety Resveratrol, found in grape skin, shuts down depression-causing enzyme in brain Date:July 29, 2019Source:University at BuffaloSummary:A new study has revealed that the plant compound resveratrol, which is found in red wine, displays anti-stress effects by blocking the expression of an enzyme related to the control of stress […]

Resveratrol shows promise for anxiety and depression

A new study has shown that the compound resveratrol found in red wine demonstrates stress relieving effects in anxiety and depression. This could be due to resveratrol’s ability to control an enzyme in the brain that is liked to stress say the researchers from the University at Buffalo in collaboration with Xuzhou Medical University in China. Image Credit: Ievgenii Meyer / Shutterstock […]

NMN May Improve the Brain-Associated Blood Vessel Cell Response to Stress

NMN treatment improves brain associated blood vessel cell survival and protects against harmful stress in metabolic disorders like diabetes. Diabetes cases continue to rise sharply worldwide. These patients are more prone to stroke with a 50% greater risk of hemorrhagic stroke—blood vessels rupturing in the brain. This is thought to be caused by the dysfunction of brain-associated blood vessel cells—endothelial […]

NMN attenuates brain injury after intracerebral hemorrhage by activating Nrf2/HO-1 signaling pathway

Replenishment of NAD+ has been shown to protect against brain disorders such as amyotrophic lateral sclerosis and ischemic stroke. However, whether this intervention has therapeutic effects in intracerebral hemorrhage (ICH) is unknown. In this study, we sought to determine the potential therapeutic value of replenishment of NAD+ in ICH. In a collagenase-induced ICH (cICH) mouse model, nicotinamide mononucleotide (NMN), a key intermediate […]

NMN Supplementation Promotes Brain Blood Vessel Rejuvenation

Scientists provide genetic evidence indicating NMN supplementation promotes rejuvenation of blood vessels providing nutrients to the brain. This April, a team of scientists from the University of Oklahoma published a study in GeroScience where they found that nicotinamide mononucleotide (NMN) supplementation reversed the effects of aging on the neurovascular units and restored cellular pathways, according to the genetic expression profiles of mouse brains. NMN supplementation may […]