Scientists find injecting mice with NAD+ booster protects against hearing loss through the activation of SIRT3, a protein that prevents damage to nerve connections between the ear and the brain.

New research reveals that nicotinamide mononucleotide protects cells critical for hearing and balance from damage caused by the chemotherapeutic cisplatin. Highlights ·        Cisplatin causes ototoxicity — ear poisoning — and reductions in the cell essential molecule nicotinamide adenine dinucleotide (NAD+). ·        The NAD+ precursor nicotinamide mononucleotide (NMN) protects cochlear cells from cisplatin-induced ototoxicity in mice, preserving […]