r David Sinclair is a Professor in the Department of Genetics and co-Director of the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School. He is best known for his work on understanding why we age and how to slow its effects. His new book “Life Span – Why we aging ,why we don’t have to […]
If aging is a disease, the best solution is …
9 Hallmarks of aging
Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice
Regulation of cerebral blood flow (CBF) to neuronal activity through neurovascular coupling (NVC) plays a critical role in maintaining healthy cognitive function.In aging, increased oxidative stress and cerebral microvascular endothelial dysfunction damage NVC, leading to cognitive decline.A growing body of evidence suggests that the decline in availability of NAD + with age plays a crucial role in a range of […]