{"id":355,"date":"2015-12-31T10:45:40","date_gmt":"2015-12-31T15:45:40","guid":{"rendered":"http:\/\/www.deepthinkgohelper.com\/wp\/?p=355"},"modified":"2022-05-23T04:22:10","modified_gmt":"2022-05-23T04:22:10","slug":"%e9%97%9c%e6%96%bc%e7%99%bd%e8%97%9c%e8%98%86%e9%86%87%ef%bc%8c%e4%bd%a0%e6%89%80%e6%87%89%e8%a9%b2%e7%9f%a5%e9%81%93%e7%9a%84%e4%b8%80%e5%88%87","status":"publish","type":"post","link":"http:\/\/johnhealth.blog\/ch\/?p=355","title":{"rendered":"\u95dc\u65bc\u767d\u85dc\u8606\u9187\uff0c\u4f60\u6240\u61c9\u8a72\u77e5\u9053\u7684\u4e00\u5207"},"content":{"rendered":"\n\n\n
 <\/p>\n\n\n\n
\n\n\n\n
\n\n\n\n
\n

\u6587\uff0f\u9ec3\u798e\u6de6 \u4e09\u91cd\u8056\u4ec1\u76ae\u819a\u79d1\u8a3a\u6240\u9662\u9577<\/p>\n

\u85cf\u5728\u300c\u6cd5\u5f0f\u77db\u76fe\u300d\u4e2d\u7684\u79d8\u65b9<\/h3>\n

\u6cd5\u570b\u4e0d\u6127\u662f\u6642\u5c1a\u767c\u6e90\u5730\uff0c\u8d70\u5728\u5df4\u9ece\u8857\u982d\u7684\u7537\u7537\u5973\u5973\u6bcf\u500b\u4eba\u770b\u4f86\u90fd\u90a3\u9ebc\u6709\u578b\u3002\u4ed6\u5011\u4e0d\u4e00\u5b9a\u8ddf\u96a8\u6f6e\u6d41\uff0c\u800c\u662f\u4eba\u4eba\u6563\u767c\u81ea\u8eab\u7368\u7279\u7684\u500b\u6027\u8207\u5473\u9053\uff0c\u800c\u628a\u9019\u4e9b\u7279\u8cea\u767c\u63ee\u5728\u88dd\u626e\u4e0a\u3002\u66f4\u68d2\u7684\u662f\u6cd5\u570b\u4fca\u7537\u7f8e\u5973\u4e0d\u6703\u53ea\u5728\u96fb\u5f71\u88e1\u6216\u6642\u5c1a\u821e\u53f0\u4e0a\u51fa\u73fe\uff0c\u800c\u662f\u8d70\u5728\u8857\u982d\u5c31\u5230\u8655\u6709\u9a5a\u559c\uff01\u53ef\u662f\u518d\u60f3\u60f3\u865f\u7a31\u300c\u6b50\u6d32\u7b2c\u4e00\u7f8e\u5973\u300d\u7b2c\u4e00\u7f8e\u5973\u51f1\u85a9\u7433\u4e39\u59ae\u8299\u5728\u8a31\u591a\u96fb\u5f71\u88e1\u541e\u96f2\u5410\u9727\u7684\u6a23\u5b50\uff0c\u60f3\u60f3\u53ef\u4ee5\u7576\u4f5c\u5168\u7403\u8b58\u5225\u7684\u7c73\u5176\u6797\u6cd5\u570b\u7f8e\u98df\uff0c\u548c\u4f60\u5728\u5df4\u9ece\u8857\u982d\u898b\u5230\u7684\u90a3\u4e9b\u4e0a\u4e86\u5e74\u7d00\u7684\u300c\u80cc\u5f71\u300d\u4fca\u7537\u7f8e\u5973\uff0c\u662f\u5426\u8b93\u4eba\u611f\u5230\u5927\u60d1\"\u5728\u7d05\u9152\u4ee5\u53ca\u91c0\u9020\u7d05\u9152\u7684\u8461\u8404\u4e2d\uff0c\u79d1\u5b78\u5bb6\u767c\u73fe\u4e86\u4e00\u7a2e\u8907\u5408\u591a\u915a\u690d\u7269\u5316\u5b78\u7269\u8cea\uff0c\u7a31\u70ba\u767d\u85dc\u8606\u9187\"\u4e0d\u89e3\uff1f\u4ed6\u5011\u62bd\u83f8\u559d\u9152\uff0c\u83dc\u55ae\u4e2d\u6c38\u9060\u4e0d\u4e4f\u9ad8\u8102\u80aa\u3001\u9ad8\u81bd\u56fa\u9187\u98df\u6750\uff0c\u800c\u4e14\u5e7e\u4e4e\u6240\u6709\u6cd5\u570b\u4eba\u90fd\u55dc\u7f8e\u98df\u5982\u547d\uff0c\u4f46\u4eba\u4eba\u8eab\u6750\u537b\u90fd\u4fdd\u6301\u5f97\u5f88\u597d\uff0c\u8857\u4e0a\u5f88\u5c11\u770b\u5230\u80d6\u5b50\uff0c\u9019\u5230\u5e95\u662f\u600e\u9ebc\u8fa6\u5230\u7684\uff1f\u4ec0\u9ebc\uff1f\u539f\u4f86\u6211\u5011\u6240\u8a8d\u70ba\u7684\u98f2\u9152\u4e0d\u826f\u7fd2\u6163\uff0c\u7adf\u7136\u662f\u4ed6\u5011\u4fdd\u6301\u8eab\u6750\u7684\u79d8\u65b9\uff1f\u800c\u4ed6\u5011\u7684\u5065\u5eb7\u7adf\u7136\u4e5f\u62dc\u7d05\u9152\u6240\u7dad\u6301\uff1f\u8981\u77e5\u9053\u6cd5\u570b\u4eba\u7684\u5fc3\u8840\u7ba1\u75be\u75c5\u7f79\u60a3\u7387\uff0c\u4e5f\u662f\u51fa\u5947\u7684\u4f4e\u5594\uff01\u9019\u5230\u5e95\u662f\u70ba\u4ec0\u9ebc\uff1f\u539f\u4f86\uff0c\u5728\u7d05\u9152\u4ee5\u53ca\u91c0\u9020\u7d05\u9152\u7684\u8461\u8404\u4e2d\uff0c\u79d1\u5b78\u5bb6\u767c\u73fe\u4e86\u4e00\u7a2e\u8907\u5408\u591a\u915a\u690d\u7269\u5316\u5b78\u7269\u8cea\uff0c\u7a31\u70ba\u767d\u85dc\u8606\u9187(resveratrol)\uff0c\u5b83\uff0c\u5c31\u662f\u96b1\u85cf\u5728\u300c\u6cd5\u5f0f\u77db\u76fe\u300d\u80cc\u5f8c\u7684\u5929\u5927\u79d8\u5bc6\uff01<\/p>\n

\u65e9\u57281992\u5e74\uff0c\u79d1\u5b78\u5bb6\u9996\u6b21\u5c0d\u767d\u85dc\u8606\u9187\u6210\u5206\u611f\u5230\u8208\u8da3\uff0c\u4ed6\u5011\u958b\u59cb\u7814\u7a76\u5176\u529f\u6548\uff0c\u8a8d\u70ba\u9019\u500b\u6210\u5206\u53ef\u4ee5\u89e3\u6c7a\u9577\u4e45\u4ee5\u4f86\u300c\u6cd5\u5f0f\u77db\u76fe\u300d\u4e4b\u8b0e\u3002\u767d\u85dc\u8606\u9187\u7684\u672c\u8cea\u662f\u4e00\u7a2e\u690d\u7269\u6297\u6bd2\u7d20(phytoalexin)\uff0c\u5c6c\u65bc\u4e8c\u82ef\u4e59\u70ef(stibenes)\u5316\u5b78\u7269\u8cea\uff0c\u9019\u662f\u7531\u65bc\u82e5\u5e72\u7a2e\u985e\u7684\u690d\u7269\uff0c\u5728\u9762\u81e8\u58d3\u529b\u3001\u50b7\u5bb3\u3001\u7d30\u83cc\u611f\u67d3\u3001\u7d2b\u5916\u7dda\u7167\u5c04\u6642\uff0c\u6703\u81ea\u9ad4\u5206\u6ccc\u51fa\u767d\u85dc\u8606\u9187\u4ee5\u53ca\u5176\u4ed6\u7a2e\u985e\u7684\u4e8c\u82ef\u4e59\u70ef\u4f5c\u70ba\u81ea\u6211\u4fdd\u8b77\u8207\u5316\u89e3\u50b7\u5bb3\u7684\u56e0\u61c9\uff0c\u96e3\u602a\u767d\u85dc\u8606\u9187\u5177\u5099\u9019\u9ebc\u5f37\u5927\u7684\u6548\u679c\uff01\u6b64\u5916\uff0c\u767d\u85dc\u8606\u9187\u7684\u5c6c\u6027\u662f\u8102\u6eb6\u6027\u8907\u5408\u7269\uff0c\u4ee5\u914d\u7cd6\u9ad4(glucoside\uff0c\u67d0\u7a2e\u690d\u7269\u6d3b\u6027\u6210\u5206)\u7684\u5f62\u5f0f\u5b58\u5728\uff0c\u5728\u63cf\u8ff0\u9019\u7a2e\u914d\u7cd6\u9ad4\u6642\u63d0\u5230\u7684\u767d\u85dc\u8606\u9187\u7518(piceid\uff0c\u7518\u70ba\u8349\u5b57\u982d)\u3001\u864e\u6756\u7518(\u8349\u5b57\u982d)\u3001\u96f2\u6749\u7518(\u8349\u5b57\u982d)\u6642\uff0c\u5176\u5be6\u90fd\u662f\u540c\u4e00\u7a2e\u6771\u897f\u3002<\/p>\n

\u63a5\u4e0b\u4f86\uff0c\u6211\u5011\u60f3\u8981\u77e5\u9053\u70ba\u4f55\u767d\u85dc\u8606\u9187\u80fd\u5c0d\u4eba\u9ad4\u7522\u751f\u5982\u6b64\u6709\u7528\u7684\u6548\u76ca\uff1f<\/p>\n

(\u4e00). \u4f4e\u5361\u98f2\u98df\u7684\u6a21\u64ec\u6548\u679c<\/h3>\n

\u9577\u4e45\u4ee5\u4f86\uff0c\u5927\u5bb6\u90fd\u5df2\u7d93\u975e\u5e38\u660e\u77ad\u4f4e\u5361\u8def\u91cc(\u4f4e\u71b1\u91cf)\u98f2\u98df\u53ef\u4ee5\u6e1b\u7de9\u8001\u5316\uff0c\u9054\u5230\u5ef6\u5e74\u76ca\u58fd\u7684\u529f\u6548\u3002\u96d6\u7136\u9ad8\u7b49\u751f\u7269\u5206\u5b50\u6a5f\u5236\u5c1a\u6709\u8a31\u591a\u5f85\u7814\u7a76\u7684\u9818\u57df\uff0c\u4f46\u6211\u5011\u6709\u5145\u5206\u7684\u7406\u7531\u76f8\u4fe1\uff0c\u6240\u6709\u7a2e\u985e\u7684\u751f\u7269\u9ad4\u5f7c\u6b64\u4e4b\u9593\u7684\u6839\u672c\u6027\u5dee\u7570\u4e26\u4e0d\u5927\u3002<\/p>\n

\u5982\u679c\u80fd\u5c07\u63d0\u4f9b\u7d66\u751f\u7269\u9ad4\u7684\u80fd\u6e90\u88dc\u5145\uff0c\u5747\u9650\u5236\u70ba\u4f4e\u5361\uff0c\u53ef\u4ee5\u4fc3\u9032\u4e00\u5957\u300c\u57fa\u56e0\u4e2d\u7684\u57fa\u56e0\u300d\u958b\u59cb\u6d3b\u52d5\uff0c\u9019\u6642\u55ae\u4e00\u7d30\u80de\u7684\u58fd\u547d\u5f97\u4ee5\u5ef6\u9577\uff0c\u5176DNA\u9060\u6bd4\u5403\u597d\u559d\u597d\u7684\u7d30\u80de\u9084\u80fd\u66f4\u6709\u6548\u7387\u7684\u9032\u884c\u81ea\u6211\u4fee\u5fa9\u3002\u66f4\u597d\u7684\u662f\u67d0\u4e9b\u4f4e\u5206\u5b50\u690d\u7269\u5929\u7136\u7269\u8cea\u6703\u6a21\u4eff\u9019\u7a2e\u6548\u679c<\/strong>\uff0c\u5982\u82e5\u5e72\u7570\u9ec3\u916e<\/strong>(\u5982\u69f2\u76ae\u7d20quercetin)\u548c\u6548\u7387\u6700\u4f73\u7684\u767d\u85dc\u8606\u9187<\/strong>(\u53ef\u5ef6\u9577\u9175\u6bcd\u7684\u58fd\u547d\u905470%\uff01)\u3002<\/p>\n

\u96d6\u7136\u76ee\u524d\u79d1\u5b78\u5bb6\u9084\u7121\u6cd5\u5b8c\u5168\u77ad\u89e3\u767d\u85dc\u8606\u9187\u7684\u4f5c\u7528\u6a5f\u5236\uff0c\u4f46\u4e00\u822c\u8a8d\u70ba\u5176\u6548\u679c\u985e\u4f3c\u65bc\u4f4e\u5361\u98f2\u98df\u7522\u751f\u7684\u6578\u9805\u6548\u76ca\u3002\u6709\u4e9b\u7814\u7a76\u6307\u51fa\uff0c\u767d\u85dc\u8606\u9187\u53ef\u4ee5\u6d3b\u5316\u67d0\u7a2e\u86cb\u767d\u8cea(Sirtuin 1\uff0c\u6216\u7a31\u70baSIRT 1)\uff0c\u4e26\u589e\u9032\u7c92\u7dda\u9ad4\u7684\u6548\u61c9\u3002\u9019\u7a2e\u86cb\u767d\u8cea\u53ef\u4ee5\u589e\u9032\u4ee3\u8b1d\u3001\u52a0\u901f\u8102\u80aa\u71c3\u71d2\uff0c\u89e3\u91cb\u4e86\u70ba\u4f55\u7576\u5176\u6548\u7387\u589e\u52a0\u6642\uff0c\u4fbf\u53ef\u9054\u5230\u548c\u4f4e\u5361\u98f2\u98df\u76f8\u4eff\u7684\u7626\u8eab\u6548\u679c\u3002<\/p>\n

(\u4e8c). \u6297\u6c27\u5316\u4f5c\u7528<\/h3>\n

\u53e6\u6709\u5831\u544a\u6307\u51fa\uff0c\u767d\u85dc\u8606\u9187\u7684\u6548\u61c9\u662f\u767c\u751f\u5728\u7d30\u80de\u4e0a\uff0c\u53ef\u6d3b\u5316\u8d85\u6c27\u5316\u7269\u6b67\u5316\u9149\u6bcf2(SOD2)\u905414\u500d\u4e4b\u591a\u3002SOD2\u53ef\u5c07\u904e\u6c27\u5316\u7269\u9084\u539f\u70ba\u904e\u6c27\u5316\u6c2b\u3002\u904e\u6c27\u5316\u7269\u662f\u9020\u6210\u81ea\u7531\u57fa\u9023\u9396\u53cd\u61c9\u7684\u5143\u5147\uff0c\u56e0\u6b64\u8b93\u7d30\u80de\u548c\u9019\u4e9b\u904e\u6c27\u5316\u9670\u96e2\u5b50\u4fdd\u6301\u8ddd\u96e2\u5f88\u91cd\u8981\u3002\u6b63\u56e0\u70baSOD2\u5177\u5099\u53ef\u5c07\u904e\u6c27\u5316\u7269\u9084\u539f\u7684\u80fd\u529b\uff0c\u4e5f\u5c31\u53ef\u4ee5\u9632\u6b62\u7c92\u7dda\u9ad4\u51cb\u4ea1\u6216\u8b8a\u6027\uff0c\u9032\u4e00\u6b65\u4f7f\u9632\u6b62\u816b\u7624\u3001\u9632\u6b62\u7f3a\u8840\u6027\u640d\u50b7(reperfusion injury)\u8207\u6c27\u5316\u50b7\u5bb3\uff0c\u9054\u6210\u5ef6\u9577\u58fd\u547d\u7684\u6548\u679c\u3002\u6b64\u5916\uff0c\u767d\u85dc\u8606\u9187\u5728\u767c\u63ee\u9078\u64c7\u6027\u96cc\u6fc0\u7d20\u53d7\u9ad4\u8abf\u7bc0\u7269(selective estrogen receptor modulator\uff0c\u7c21\u7a31SERM)\u6291\u5236\u5291\u8207\u82b3\u9999\u9149\u6bcf(aromatase)\u6291\u5236\u5291\u529f\u80fd\u7684\u540c\u6642\uff0c\u4ea6\u80fd\u5920\u5927\u5e45\u63d0\u5347\u776a\u56fa\u916e(testosterone)\u7684\u88fd\u9020\u30022007\u5e74\u7f85\u5fb9\u65af\u7279\u5927\u5b78\u7684\u7814\u7a76\u986f\u793a\uff0c\u767d\u85dc\u8606\u9187\u53ef\u589e\u9032\u80ba\u90e8\u4e0a\u76ae\u7d30\u80de\u7684\u7d30\u80de\u9593\u7684\u8c37\u80f1\u7518\u6708\u592a(glutathione)\u542b\u91cf\uff0c\u56e0\u6b64\u53ef\u964d\u4f4e\u56e0\u5438\u83f8\u5f15\u8d77\u7684\u6c27\u5316\u58d3\u529b\u3002<\/p>\n

(\u4e09). \u5c0d\u8166\u8207\u5fc3\u8840\u7ba1\u7684\u6548\u76ca<\/h3>\n

\u53e6\u5916\u9084\u6709\u5eb7\u4e43\u723e\u5927\u5b78\u7684\u5be6\u9a57\u8b49\u660e\uff0c\u6b63\u7531\u65bc\u767d\u85dc\u8606\u9187\u53ef\u4ee5\u87af\u5408\u9285\u96e2\u5b50\uff0c\u56e0\u6b64\u5927\u5e45\u589e\u52a0\u767d\u85dc\u8606\u9187\u7684\u6bcf\u65e5\u71df\u990a\u88dc\u5145\u54c1\u651d\u53d6\u91cf\uff0c\u53ef\u964d\u4f4e\u4e0b\u4e18\u8166\u3001\u7d0b\u72c0\u9ad4(stritum)\u4e2d\u7684\u75a4\u75d5\u7d44\u7e54(plague)\u5f62\u6210\uff0c\u4e26\u5c0d\u795e\u7d93\u7d30\u80de\u5931\u80fd\u8207\u7d30\u80de\u51cb\u4ea1\u7522\u751f\u6297\u8861\u4f5c\u7528\uff0c\u4ee5\u4e0a\u7686\u70ba\u963f\u8332\u6d77\u9ed8\u75c7\u3001\u4ea8\u4e01\u9813\u821e\u8e48\u75c7\u8207\u5176\u4ed6\u795e\u7d93\u9000\u5316\u75c7\u72c0\u7684\u91cd\u8981\u6210\u56e0\u3002\u53e6\u4e00\u9805\u7de9\u885d\u963f\u8332\u6d77\u9ed8\u75c7\u6210\u5f62\u7684\u6a5f\u5236\uff0c\u5728\u65bc\u53e3\u670d\u767d\u85dc\u8606\u9187\u9084\u80fd\u9632\u6b62\u4e59\u578b\u6fb1\u7c89\u6a23\u86cb\u767d(beta amyloid)\u5728\u8166\u90e8\u7684\u5806\u7a4d\uff0c\u963b\u65b7\u63a5\u4e0b\u4f86\u8840\u7ba1\u65b0\u751f\uff0c\u6700\u5f8c\u5c0e\u81f4\u963f\u8332\u6d77\u9ed8\u75c7\u5f62\u6210\u7684\u53ef\u80fd\u3002<\/em><\/p>\n

\u76ee\u524d\u5728\u52d5\u7269\u5be6\u9a57\u4e2d\uff0c\u5df2\u7d93\u767c\u73fe\u767d\u85dc\u8606\u9187\u53ef\u4ee5\u9054\u5230\u4ee5\u4e0b\u7684\u4f5c\u7528\uff1a\u6297\u764c\u3001\u6297\u767c\u708e\u3001\u964d\u4f4e\u8840\u7cd6\u6307\u6578\uff0c\u4ee5\u53ca\u6578\u9805\u5c0d\u5fc3\u8840\u7ba1\u7522\u751f\u7684\u76ca\u8655\u3002\u79d1\u5b78\u5bb6\u96d6\u7136\u4e0d\u80fd\u5b8c\u5168\u5c07\u5176\u89e3\u91cb\u70ba\u767d\u85dc\u8606\u9187\u5f97\u4ee5\u5ef6\u9577\u58fd\u547d\uff0c\u4f46\u8a66\u60f3\u4e00\u65e6\u53ef\u4ee5\u907f\u514d\u4e0a\u8ff0\u75be\u75c5\u5a01\u8105\uff0c\u80af\u5b9a\u80fd\u5920\u63d0\u9ad8\u4eba\u985e\u7684\u5e73\u5747\u5b58\u6d3b\u5e74\u9f61\u3002<\/em>\u6b64\u5916\u5728\u4fc4\u4ea5\u4fc4\u5927\u5b78\u9032\u884c\u7684\u7814\u7a76\u767c\u73fe\uff0c\u767d\u85dc\u8606\u9187\u5177\u6709\u76f4\u63a5\u6291\u5236\u5fc3\u808c\u6210\u7e96\u7dad\u7d30\u80de(cardiac bibroblast)\u4f5c\u7528\uff0c\u56e0\u6b64\u53ef\u80fd\u5177\u5099\u9632\u6b62\u5fc3\u808c\u7e96\u7dad\u5316(cardiac fibrosis)\u7684\u529f\u80fd\u3002<\/p>\n

(\u56db). \u9632\u764c\u6a5f\u5236<\/h3>\n

\u5168\u7403\u79d1\u5b78\u5bb6\u91dd\u5c0d\u767d\u85dc\u8606\u9187\u7684\u9810\u9632\u816b\u7624\u6548\u61c9\u505a\u4e86\u4e00\u7cfb\u5217\u5be6\u9a57\uff0c\u5230\u76ee\u524d\u70ba\u6b62\u7684\u975e\u4eba\u9ad4\u5be6\u9a57\u5c55\u73fe\u4e86\u8c50\u78a9\u7684\u6210\u679c\u3002\u5be6\u9a57\u4e2d\u5c07\u767d\u85dc\u8606\u9187\u6ce8\u5c04\u81f3\u5206\u5b50\u5167\uff0c\u8b49\u5be6\u5c0d\u65bc\u4e73\u764c\u3001\u76ae\u819a\u764c\u3001\u80c3\u764c\u3001\u76f4\u8178\u764c\u3001\u98df\u9053\u764c\u3001\u524d\u5217\u817a\u764c\u3001\u80f0\u81df\u764c\u8207\u767d\u8840\u75c5\u7686\u6709\u6b63\u9762\u6548\u61c9\u3002\u6548\u679c\u6700\u4f73\u7684\u662f\u816b\u7624\u5f97\u4ee5\u548c\u767d\u85dc\u8606\u9187\u76f4\u63a5\u63a5\u89f8\u7684\u75c5\u4f8b\uff0c\u5982\u76ae\u819a\u3001\u98df\u9053\u548c\u6d88\u5316\u9053\u7684\u816b\u7624\u90fd\u51fa\u73fe\u6578\u91cf\u548c\u9ad4\u7a4d\u6e1b\u5c11\u7684\u73fe\u8c61\u3002\u53ef\u4ee5\u8aaa\u5728\u816b\u7624\u767c\u5c55\u7684\u5404\u968e\u6bb5\uff0c\u7121\u8ad6\u662f\u8d77\u59cb\u671f(initiation)\u3001\u4fc3\u9032\u671f(promotion)\u3001\u9032\u5c55\u671f(progression)\uff0c\u767d\u85dc\u8606\u9187\u90fd\u80fd\u767c\u63ee\u963b\u65b7\u4f5c\u7528\u3002\u7d30\u80de\u5be6\u9a57\u767c\u73fe\u767d\u85dc\u8606\u9187\u53ef\u5c0d\u65bc\u4e9e\u7d30\u80de\u7cfb\u7d71\u7522\u751f\u85e5\u7406\u4f5c\u7528\uff0c\u53ef\u8abf\u63a7NF-kB\u8f49\u9304\u56e0\u5b50\u3001\u6291\u5236\u7d30\u80de\u8272\u7d20P450\u548c\u540c\u529f\u8122CYP1A1\u3002\u6b64\u5916\u9084\u767c\u73fe\u767d\u85dc\u8606\u9187\u53ef\u4ee5\u6291\u5236\u4eba\u985e\u80f0\u81df\u764c\u7684\u764c\u7d30\u80de\u682a(cell lines)\u64f4\u6563\u4e26\u5177\u6709\u6297\u6c27\u5316\u8207\u6297\u8840\u7ba1\u65b0\u751f(anti-angiogenic)\u7684\u7279\u6027\u3002\u8840\u7ba1\u65b0\u751f\u96d6\u7136\u5728\u4eba\u9ad4\u751f\u9577\u548c\u50b7\u53e3\u7652\u5408\u4e0a\u626e\u6f14\u6b63\u9762\u7684\u89d2\u8272\uff0c\u4f46\u816b\u7624\u5f62\u6210\u6642\u4e5f\u6703\u4fc3\u4f7f\u8840\u7ba1\u65b0\u751f\u904e\u5ea6\u4f5c\u7528\uff0c\u9020\u6210\u764c\u7d30\u80de\u64f4\u6563\uff0c\u6211\u5011\u5728\u963f\u8332\u6d77\u9ed8\u75c7\u7684\u6bb5\u843d\u4ea6\u8a0e\u8ad6\u904e\u8840\u7ba1\u589e\u751f\u7684\u5f0a\u75c5\u3002<\/p>\n

\u98df\u7269\u4f86\u6e90<\/h3>\n

\u96d6\u8aaa\u767d\u85dc\u8606\u9187\u53ea\u6709\u5728\u690d\u7269\u4e0a\u624d\u80fd\u627e\u5230\uff0c\u4f46\u4e5f\u4e0d\u662f\u6bcf\u7a2e\u690d\u7269\u90fd\u6709\u3002\u542b\u91cf\u6700\u8c50\u5bcc\u4f86\"\u767d\u85dc\u8606\u9187\u542b\u91cf\u6700\u8c50\u5bcc\u7684\u4f86\u6e90\u5305\u62ec\u8461\u8404\u3001\u8461\u8404\u6c41\u548c\u7d05\u9152\"\u6e90\u5305\u62ec\u8461\u8404\u3001\u8461\u8404\u6c41\u548c\u7d05\u9152\uff0c\u5c24\u5176\u662f\u7d05\u9152\u7684\u542b\u91cf\u6700\u8c50\u5bcc\u3002\u6b64\u5916\u542b\u6709\u767d\u85dc\u8606\u9187\u7684\u53ef\u98df\u7528\u4f86\u6e90\u5c31\u53ea\u6709\u8d8a\u6a58\u5c6c(Vaccinium)\u8393\u679c\u985e\u5982\u85cd\u8393\u3001\u8d8a\u6a58(\u5c71\u6851\u5b50)\u3001\u5c0f\u7d05\u8393\u7b49\u4ee5\u53ca\u82b1\u751f\u3002\u5c31\u8461\u8404\u800c\u8a00\uff0c<\/em>\u767d\u85dc\u8606\u9187\u53ea\u5b58\u5728\u65bc\u679c\u76ae\u4e2d\uff0c\u800c\u9152\u4e2d\u7684\u767d\u85dc\u8606\u9187\u542b\u91cf\u5c31\u8981\u770b\u8461\u8404\u76ae\u7684\u767c\u9175\u6642\u9593\u591a\u5c11\u800c\u5b9a\uff0c\u4e5f\u5c31\u56e0\u6b64\uff0c\u767d\u9152\u548c\u7c89\u7d05\u9152\u4e2d\u7684\u542b\u91cf\u5c31\u6bd4\u7d05\u9152\u5c11\u3002\u7d05\u8272\u6216\u7d2b\u8272\u8461\u8404\u6c41\u4ea6\u662f\u826f\u597d\u7684\u767d\u85dc\u8606\u9187\u98df\u7269\u4f86\u6e90\u3002\u4e0d\u904e\u8c50\u5bcc\u7684\u767d\u85dc\u8606\u9187\u4e4b\u5916\uff0c\u7d05\u9152\u9084\u542b\u6709\u5176\u4ed6\u7684\u591a\u915a\u985e\uff0c\u6fc3\u5ea6\u751a\u81f3\u6bd4\u767d\u85dc\u8606\u9187\u66f4\u9ad8(\u5982\u985e\u9ec3\u916eflavonoids)\u3002\u4e0b\u8868\u53ef\u898b\u5728\u98f2\u6599\u548c\u98df\u7269\u4e2d\u7684\u767d\u85dc\u8606\u9187\u542b\u91cf\uff1a<\/p>\n\n\n\n
\n\n\n\n\n\n\n\n\n\n
\n
\u8461\u8404\u9152\u8207\u8461\u8404\u6c41<\/span>\u7684\u767d\u85dc\u8606\u9187\u7e3d\u542b\u91cf<\/span>
\n<\/span><\/div>\n<\/td>\n<\/tr>\n
\n
\u98f2\u6599<\/strong><\/div>\n<\/td>\n
\n
\u767d\u85dc\u8606\u9187\u7e3d\u542b\u91cf<\/strong>
\n(<\/strong>\u6beb\u514b<\/strong>mg\/<\/strong>\u516c\u5347<\/strong>liter)<\/strong><\/div>\n<\/td>\n
\n
5<\/strong>\u76ce\u53f8\u7684\u73bb\u7483\u74f6\u88dd\u4e2d\u767d\u85dc\u8606\u9187\u7e3d\u542b\u91cf<\/strong> (<\/strong>\u6beb\u514b<\/strong>mg)<\/strong><\/div>\n<\/td>\n<\/tr>\n
\n
\u767d\u9152 (\u897f\u73ed\u7259\u54c1\u7a2e)<\/div>\n<\/td>\n
\n
0.05-1.80<\/div>\n<\/td>\n
\n

0.01-0.27<\/p>\n<\/td>\n<\/tr>\n

\n
\u7c89\u7d05\u9152 (\u897f\u73ed\u7259\u54c1\u7a2e)<\/div>\n<\/td>\n
\n

0.43-3.52<\/p>\n<\/td>\n

\n

0.06-0.53<\/p>\n<\/td>\n<\/tr>\n

\n
\u7d05\u9152 (\u897f\u73ed\u7259\u54c1\u7a2e)<\/div>\n<\/td>\n
\n

1.92-12.59<\/p>\n<\/td>\n

\n

0.29-1.89<\/p>\n<\/td>\n<\/tr>\n

\n
\u7d05\u9152 (\u5168\u7403\u54c1\u7a2e)<\/div>\n<\/td>\n
\n

1.98-7.13<\/p>\n<\/td>\n

\n

0.30-1.07<\/p>\n<\/td>\n<\/tr>\n

\n
\u7d05\u8461\u8404\u6c41 (\u897f\u73ed\u7259\u54c1\u7a2e)<\/div>\n<\/td>\n
\n

1.14-8.69<\/p>\n<\/td>\n

\n

0.17-1.30<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n
\n\n\n\n\n\n\n\n\n
\n

\u82e5\u5e72\u98df\u7269\u4e2d\u7684\u767d\u85dc\u8606\u9187\u7e3d\u542b\u91cf<\/strong><\/p>\n<\/td>\n<\/tr>\n

\n

\u98df\u7269<\/strong><\/p>\n<\/td>\n

\n

\u4efd\u91cf<\/strong><\/p>\n<\/td>\n

\n

\u767d\u85dc\u8606\u9187\u7e3d\u542b\u91cf<\/strong>(<\/strong>\u55ae\u4f4d\uff1a\u6beb\u514b<\/strong>mg)<\/strong><\/p>\n<\/td>\n<\/tr>\n

\n

\u82b1\u751f (\u751f)<\/p>\n<\/td>\n

\n

1\u7897 (146\u514b)<\/p>\n<\/td>\n

\n

0.01-0.26<\/p>\n<\/td>\n<\/tr>\n

\n

\u82b1\u751f (\u719f)<\/p>\n<\/td>\n

\n

1\u7897 (180\u514b)<\/p>\n<\/td>\n

\n

0.32-1.28<\/p>\n<\/td>\n<\/tr>\n

\n

\u82b1\u751f\u6cb9<\/p>\n<\/td>\n

\n

1\u7897 (258\u514b)<\/p>\n<\/td>\n

\n

0.04-0.13<\/p>\n<\/td>\n<\/tr>\n

\n

\u7d05\u8461\u8404<\/p>\n<\/td>\n

\n

1\u7897 (160\u514b)<\/p>\n<\/td>\n

\n

0.24-1.25<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u71df\u990a\u88dc\u5145\u54c1<\/h3>\n

\u5927\u90e8\u5206\u7684\u767d\u85dc\u8606\u9187\u5065\u5eb7\u98df\u54c1\u90fd\u662f\u63d0\u7149\u81ea\u864e\u6756(Polygonum cuspidatum\uff0c\u4e2d\u85e5\u6750\u7684\u4e00\u7a2e)\u7684\u6839\uff0c\u4e5f\u6709\u5f9e\u7d05\u9152\u548c\u7d05\u8461\u8404\u4e2d\u63d0\u7149\u51fa\u7684\u767d\u85dc\u8606\u9187\u5065\u5eb7\u98df\u54c1\u3002\u4e0d\u904e\uff0c\u864e\u6756\u8403\u53d6\u7684\u5065\u5eb7\u98df\u54c1\uff0c\u54c1\u8cea\u4e00\u822c\u8aaa\u4f86\u6bd4\u4e0d\u4e0a\u7d05\u8461\u8404\u8403\u53d6\u4f86\u5f97\u7a69\u5b9a\u6216\u7d14\u7cb9\uff0c\u7136\u800c\u7531\u8461\u8404\u6240\u63d0\u7149\u51fa\u7684\u7522\u54c1\uff0c\u4e5f\u6703\u53d7\u5230\u8a72\u63a1\u6536\u5e74\u7684\u96e8\u6c34\u3001\u571f\u58e4\u7b49\u72c0\u6cc1\u5f71\u97ff\u3002\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0c\u76ee\u524d\u767d\u85dc\u8606\u9187\u552f\u4e00\u7684\u4eba\u9ad4\u8a66\u9a57\u662f\u5728\u65e5\u672c\u9032\u884c\uff0c\u5be6\u9a57\u6240\u7528\u5291\u91cf\u5f88\u9ad8(3~5g)\uff0c\u4f5c\u70ba\u964d\u4f4e\u8840\u7cd6\u7684\u7528\u9014\uff0c\u800c\u65e5\u672c\u6240\u8ca9\u552e\u7684\u5065\u5eb7\u98df\u54c1\u662f\u7531\u65e5\u672c\u864e\u6756\u63d0\u7149\u800c\u4f86\u3002<\/p>\n

\u76ee\u524d\u5e38\u898b\u7684\u81a0\u56ca\u98df\u54c1\u55ae\u9846\u5291\u91cf\u7bc4\u570d\u70ba10~50mg\uff0c\u800c\u5728\u5b89\u5168\u6027\u65b9\u9762\uff0c\u76ee\u524d\u4e26\u672a\u767c\u73fe\u767d\u85dc\u8606\u9187\u5c0d\u4eba\u9ad4\u6709\u4efb\u4f55\u6bd2\u6027\u6216\u526f\u4f5c\u7528\u3002\u6b64\u5916\uff0c\u96d6\u7136\u76ee\u524d\u5c1a\u672a\u5efa\u7acb\u61f7\u5b55\u548c\u6ccc\u4e73\u671f\u9593\u7684\u5a66\u5973\u662f\u5426\u53ef\u4ee5\u5b89\u5fc3\u670d\u7528\u7684\u6578\u64da\uff0c\u4e0d\u904e\u6211\u5011\u8981\u547c\u7c72\u5b55\u671f\u5a66\u5973\u61c9\u907f\u514d\u5c07\u98f2\u7528\u7d05\u9152\u4f5c\u70ba\u651d\u53d6\u767d\u85dc\u8606\u9187\u7684\u98df\u7269\u4f86\u6e90\u3002<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u51fa\u5904\uff1ahttp:\/\/www.newskinhouse.com.tw\/news_2.php?product_id=1339552230<\/a><\/p>\n

\u6ce8\uff1a\u9019\u662f\u4e00\u7bc72012\u5e74\u7684\u6587\u7ae0\u3002\u73fe\u5728\u95dc\u4e8e\u767d\u85dc\u8606\u9187\u7684\u7814\u7a76\u6210\u679c\u4e0d\u65b7\uff0c\u767d\u85dc\u8606\u9187\u200b\u7684\u529f\u6548\u88ab\u4e0d\u65b7\u767c\u6398\uff0c\u76ee\u524d\u7232\u6b62\u9084\u6c92\u6709\u767c\u73fe\u6709\u526f\u4f5c\u7528\u3002\u9700\u8981\u4e3b\u610f\u7684\u662f \u767d\u85dc\u8606\u9187\u200b\u6709\u7a00\u91cb\u8840\u6db2\u7684\u529f\u6548\uff0c\u56e0\u6b64\u6709\u4f7f\u7528\u7a00\u91cb\u200b\u8840\u6db2\u7684\u60a3\u8005\uff0c\u4f7f\u7528\u7684\u6642\u5019\u9700\u8981\u6ce8\u610f\u3002<\/div>\n
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  \u6587\uff0f\u9ec3\u798e\u6de6 \u4e09\u91cd\u8056\u4ec1\u76ae\u819a\u79d1\u8a3a\u6240\u9662\u9577 \u85cf\u5728\u300c\u6cd5\u5f0f\u77db\u76fe\u300d\u4e2d\u7684\u79d8\u65b9 \u6cd5\u570b\u4e0d\u6127\u662f\u6642\u5c1a\u767c\u6e90\u5730\uff0c\u8d70\u5728\u5df4\u9ece\u8857\u982d\u7684\u7537\u7537\u5973\u5973\u6bcf\u500b\u4eba\u770b\u4f86\u90fd\u90a3\u9ebc\u6709\u578b\u3002\u4ed6\u5011\u4e0d\u4e00\u5b9a\u8ddf\u96a8\u6f6e\u6d41\uff0c\u800c\u662f\u4eba\u4eba\u6563\u767c\u81ea\u8eab\u7368\u7279\u7684\u500b\u6027\u8207\u5473\u9053\uff0c\u800c\u628a\u9019\u4e9b\u7279\u8cea\u767c\u63ee\u5728\u88dd\u626e\u4e0a\u3002\u66f4\u68d2\u7684\u662f\u6cd5\u570b\u4fca\u7537\u7f8e\u5973\u4e0d\u6703\u53ea\u5728\u96fb\u5f71\u88e1\u6216\u6642\u5c1a\u821e\u53f0\u4e0a\u51fa\u73fe\uff0c\u800c\u662f\u8d70\u5728\u8857\u982d\u5c31\u5230\u8655\u6709\u9a5a\u559c\uff01\u53ef\u662f\u518d\u60f3\u60f3\u865f\u7a31\u300c\u6b50\u6d32\u7b2c\u4e00\u7f8e\u5973\u300d\u7b2c\u4e00\u7f8e\u5973\u51f1\u85a9\u7433\u4e39\u59ae\u8299\u5728\u8a31\u591a\u96fb\u5f71\u88e1\u541e\u96f2\u5410\u9727\u7684\u6a23\u5b50\uff0c\u60f3\u60f3\u53ef\u4ee5\u7576\u4f5c\u5168\u7403\u8b58\u5225\u7684\u7c73\u5176\u6797\u6cd5\u570b\u7f8e\u98df\uff0c\u548c\u4f60\u5728\u5df4\u9ece\u8857\u982d\u898b\u5230\u7684\u90a3\u4e9b\u4e0a\u4e86\u5e74\u7d00\u7684\u300c\u80cc\u5f71\u300d\u4fca\u7537\u7f8e\u5973\uff0c\u662f\u5426\u8b93\u4eba\u611f\u5230\u5927\u60d1\u4e0d\u89e3\uff1f\u4ed6\u5011\u62bd\u83f8\u559d\u9152\uff0c\u83dc\u55ae\u4e2d\u6c38\u9060\u4e0d\u4e4f\u9ad8\u8102\u80aa\u3001\u9ad8\u81bd\u56fa\u9187\u98df\u6750\uff0c\u800c\u4e14\u5e7e\u4e4e\u6240\u6709\u6cd5\u570b\u4eba\u90fd\u55dc\u7f8e\u98df\u5982\u547d\uff0c\u4f46\u4eba\u4eba\u8eab\u6750\u537b\u90fd\u4fdd\u6301\u5f97\u5f88\u597d\uff0c\u8857\u4e0a\u5f88\u5c11\u770b\u5230\u80d6\u5b50\uff0c\u9019\u5230\u5e95\u662f\u600e\u9ebc\u8fa6\u5230\u7684\uff1f\u4ec0\u9ebc\uff1f\u539f\u4f86\u6211\u5011\u6240\u8a8d\u70ba\u7684\u98f2\u9152\u4e0d\u826f\u7fd2\u6163\uff0c\u7adf\u7136\u662f\u4ed6\u5011\u4fdd\u6301\u8eab\u6750\u7684\u79d8\u65b9\uff1f\u800c\u4ed6\u5011\u7684\u5065\u5eb7\u7adf\u7136\u4e5f\u62dc\u7d05\u9152\u6240\u7dad\u6301\uff1f\u8981\u77e5\u9053\u6cd5\u570b\u4eba\u7684\u5fc3\u8840\u7ba1\u75be\u75c5\u7f79\u60a3\u7387\uff0c\u4e5f\u662f\u51fa\u5947\u7684\u4f4e\u5594\uff01\u9019\u5230\u5e95\u662f\u70ba\u4ec0\u9ebc\uff1f\u539f\u4f86\uff0c\u5728\u7d05\u9152\u4ee5\u53ca\u91c0\u9020\u7d05\u9152\u7684\u8461\u8404\u4e2d\uff0c\u79d1\u5b78\u5bb6\u767c\u73fe\u4e86\u4e00\u7a2e\u8907\u5408\u591a\u915a\u690d\u7269\u5316\u5b78\u7269\u8cea\uff0c\u7a31\u70ba\u767d\u85dc\u8606\u9187(resveratrol)\uff0c\u5b83\uff0c\u5c31\u662f\u96b1\u85cf\u5728\u300c\u6cd5\u5f0f\u77db\u76fe\u300d\u80cc\u5f8c\u7684\u5929\u5927\u79d8\u5bc6\uff01 \u65e9\u57281992\u5e74\uff0c\u79d1\u5b78\u5bb6\u9996\u6b21\u5c0d\u767d\u85dc\u8606\u9187\u6210\u5206\u611f\u5230\u8208\u8da3\uff0c\u4ed6\u5011\u958b\u59cb\u7814\u7a76\u5176\u529f\u6548\uff0c\u8a8d\u70ba\u9019\u500b\u6210\u5206\u53ef\u4ee5\u89e3\u6c7a\u9577\u4e45\u4ee5\u4f86\u300c\u6cd5\u5f0f\u77db\u76fe\u300d\u4e4b\u8b0e\u3002\u767d\u85dc\u8606\u9187\u7684\u672c\u8cea\u662f\u4e00\u7a2e\u690d\u7269\u6297\u6bd2\u7d20(phytoalexin)\uff0c\u5c6c\u65bc\u4e8c\u82ef\u4e59\u70ef(stibenes)\u5316\u5b78\u7269\u8cea\uff0c\u9019\u662f\u7531\u65bc\u82e5\u5e72\u7a2e\u985e\u7684\u690d\u7269\uff0c\u5728\u9762\u81e8\u58d3\u529b\u3001\u50b7\u5bb3\u3001\u7d30\u83cc\u611f\u67d3\u3001\u7d2b\u5916\u7dda\u7167\u5c04\u6642\uff0c\u6703\u81ea\u9ad4\u5206\u6ccc\u51fa\u767d\u85dc\u8606\u9187\u4ee5\u53ca\u5176\u4ed6\u7a2e\u985e\u7684\u4e8c\u82ef\u4e59\u70ef\u4f5c\u70ba\u81ea\u6211\u4fdd\u8b77\u8207\u5316\u89e3\u50b7\u5bb3\u7684\u56e0\u61c9\uff0c\u96e3\u602a\u767d\u85dc\u8606\u9187\u5177\u5099\u9019\u9ebc\u5f37\u5927\u7684\u6548\u679c\uff01\u6b64\u5916\uff0c\u767d\u85dc\u8606\u9187\u7684\u5c6c\u6027\u662f\u8102\u6eb6\u6027\u8907\u5408\u7269\uff0c\u4ee5\u914d\u7cd6\u9ad4(glucoside\uff0c\u67d0\u7a2e\u690d\u7269\u6d3b\u6027\u6210\u5206)\u7684\u5f62\u5f0f\u5b58\u5728\uff0c\u5728\u63cf\u8ff0\u9019\u7a2e\u914d\u7cd6\u9ad4\u6642\u63d0\u5230\u7684\u767d\u85dc\u8606\u9187\u7518(piceid\uff0c\u7518\u70ba\u8349\u5b57\u982d)\u3001\u864e\u6756\u7518(\u8349\u5b57\u982d)\u3001\u96f2\u6749\u7518(\u8349\u5b57\u982d)\u6642\uff0c\u5176\u5be6\u90fd\u662f\u540c\u4e00\u7a2e\u6771\u897f\u3002 \u63a5\u4e0b\u4f86\uff0c\u6211\u5011\u60f3\u8981\u77e5\u9053\u70ba\u4f55\u767d\u85dc\u8606\u9187\u80fd\u5c0d\u4eba\u9ad4\u7522\u751f\u5982\u6b64\u6709\u7528\u7684\u6548\u76ca\uff1f (\u4e00). \u4f4e\u5361\u98f2\u98df\u7684\u6a21\u64ec\u6548\u679c \u9577\u4e45\u4ee5\u4f86\uff0c\u5927\u5bb6\u90fd\u5df2\u7d93\u975e\u5e38\u660e\u77ad\u4f4e\u5361\u8def\u91cc(\u4f4e\u71b1\u91cf)\u98f2\u98df\u53ef\u4ee5\u6e1b\u7de9\u8001\u5316\uff0c\u9054\u5230\u5ef6\u5e74\u76ca\u58fd\u7684\u529f\u6548\u3002\u96d6\u7136\u9ad8\u7b49\u751f\u7269\u5206\u5b50\u6a5f\u5236\u5c1a\u6709\u8a31\u591a\u5f85\u7814\u7a76\u7684\u9818\u57df\uff0c\u4f46\u6211\u5011\u6709\u5145\u5206\u7684\u7406\u7531\u76f8\u4fe1\uff0c\u6240\u6709\u7a2e\u985e\u7684\u751f\u7269\u9ad4\u5f7c\u6b64\u4e4b\u9593\u7684\u6839\u672c\u6027\u5dee\u7570\u4e26\u4e0d\u5927\u3002 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\u96d6\u7136\u76ee\u524d\u79d1\u5b78\u5bb6\u9084\u7121\u6cd5\u5b8c\u5168\u77ad\u89e3\u767d\u85dc\u8606\u9187\u7684\u4f5c\u7528\u6a5f\u5236\uff0c\u4f46\u4e00\u822c\u8a8d\u70ba\u5176\u6548\u679c\u985e\u4f3c\u65bc\u4f4e\u5361\u98f2\u98df\u7522\u751f\u7684\u6578\u9805\u6548\u76ca\u3002\u6709\u4e9b\u7814\u7a76\u6307\u51fa\uff0c\u767d\u85dc\u8606\u9187\u53ef\u4ee5\u6d3b\u5316\u67d0\u7a2e\u86cb\u767d\u8cea(Sirtuin 1\uff0c\u6216\u7a31\u70baSIRT 1)\uff0c\u4e26\u589e\u9032\u7c92\u7dda\u9ad4\u7684\u6548\u61c9\u3002\u9019\u7a2e\u86cb\u767d\u8cea\u53ef\u4ee5\u589e\u9032\u4ee3\u8b1d\u3001\u52a0\u901f\u8102\u80aa\u71c3\u71d2\uff0c\u89e3\u91cb\u4e86\u70ba\u4f55\u7576\u5176\u6548\u7387\u589e\u52a0\u6642\uff0c\u4fbf\u53ef\u9054\u5230\u548c\u4f4e\u5361\u98f2\u98df\u76f8\u4eff\u7684\u7626\u8eab\u6548\u679c\u3002 (\u4e8c). \u6297\u6c27\u5316\u4f5c\u7528 \u53e6\u6709\u5831\u544a\u6307\u51fa\uff0c\u767d\u85dc\u8606\u9187\u7684\u6548\u61c9\u662f\u767c\u751f\u5728\u7d30\u80de\u4e0a\uff0c\u53ef\u6d3b\u5316\u8d85\u6c27\u5316\u7269\u6b67\u5316\u9149\u6bcf2(SOD2)\u905414\u500d\u4e4b\u591a\u3002SOD2\u53ef\u5c07\u904e\u6c27\u5316\u7269\u9084\u539f\u70ba\u904e\u6c27\u5316\u6c2b\u3002\u904e\u6c27\u5316\u7269\u662f\u9020\u6210\u81ea\u7531\u57fa\u9023\u9396\u53cd\u61c9\u7684\u5143\u5147\uff0c\u56e0\u6b64\u8b93\u7d30\u80de\u548c\u9019\u4e9b\u904e\u6c27\u5316\u9670\u96e2\u5b50\u4fdd\u6301\u8ddd\u96e2\u5f88\u91cd\u8981\u3002\u6b63\u56e0\u70baSOD2\u5177\u5099\u53ef\u5c07\u904e\u6c27\u5316\u7269\u9084\u539f\u7684\u80fd\u529b\uff0c\u4e5f\u5c31\u53ef\u4ee5\u9632\u6b62\u7c92\u7dda\u9ad4\u51cb\u4ea1\u6216\u8b8a\u6027\uff0c\u9032\u4e00\u6b65\u4f7f\u9632\u6b62\u816b\u7624\u3001\u9632\u6b62\u7f3a\u8840\u6027\u640d\u50b7(reperfusion injury)\u8207\u6c27\u5316\u50b7\u5bb3\uff0c\u9054\u6210\u5ef6\u9577\u58fd\u547d\u7684\u6548\u679c\u3002\u6b64\u5916\uff0c\u767d\u85dc\u8606\u9187\u5728\u767c\u63ee\u9078\u64c7\u6027\u96cc\u6fc0\u7d20\u53d7\u9ad4\u8abf\u7bc0\u7269(selective estrogen receptor modulator\uff0c\u7c21\u7a31SERM)\u6291\u5236\u5291\u8207\u82b3\u9999\u9149\u6bcf(aromatase)\u6291\u5236\u5291\u529f\u80fd\u7684\u540c\u6642\uff0c\u4ea6\u80fd\u5920\u5927\u5e45\u63d0\u5347\u776a\u56fa\u916e(testosterone)\u7684\u88fd\u9020\u30022007\u5e74\u7f85\u5fb9\u65af\u7279\u5927\u5b78\u7684\u7814\u7a76\u986f\u793a\uff0c\u767d\u85dc\u8606\u9187\u53ef\u589e\u9032\u80ba\u90e8\u4e0a\u76ae\u7d30\u80de\u7684\u7d30\u80de\u9593\u7684\u8c37\u80f1\u7518\u6708\u592a(glutathione)\u542b\u91cf\uff0c\u56e0\u6b64\u53ef\u964d\u4f4e\u56e0\u5438\u83f8\u5f15\u8d77\u7684\u6c27\u5316\u58d3\u529b\u3002 (\u4e09). \u5c0d\u8166\u8207\u5fc3\u8840\u7ba1\u7684\u6548\u76ca \u53e6\u5916\u9084\u6709\u5eb7\u4e43\u723e\u5927\u5b78\u7684\u5be6\u9a57\u8b49\u660e\uff0c\u6b63\u7531\u65bc\u767d\u85dc\u8606\u9187\u53ef\u4ee5\u87af\u5408\u9285\u96e2\u5b50\uff0c\u56e0\u6b64\u5927\u5e45\u589e\u52a0\u767d\u85dc\u8606\u9187\u7684\u6bcf\u65e5\u71df\u990a\u88dc\u5145\u54c1\u651d\u53d6\u91cf\uff0c\u53ef\u964d\u4f4e\u4e0b\u4e18\u8166\u3001\u7d0b\u72c0\u9ad4(stritum)\u4e2d\u7684\u75a4\u75d5\u7d44\u7e54(plague)\u5f62\u6210\uff0c\u4e26\u5c0d\u795e\u7d93\u7d30\u80de\u5931\u80fd\u8207\u7d30\u80de\u51cb\u4ea1\u7522\u751f\u6297\u8861\u4f5c\u7528\uff0c\u4ee5\u4e0a\u7686\u70ba\u963f\u8332\u6d77\u9ed8\u75c7\u3001\u4ea8\u4e01\u9813\u821e\u8e48\u75c7\u8207\u5176\u4ed6\u795e\u7d93\u9000\u5316\u75c7\u72c0\u7684\u91cd\u8981\u6210\u56e0\u3002\u53e6\u4e00\u9805\u7de9\u885d\u963f\u8332\u6d77\u9ed8\u75c7\u6210\u5f62\u7684\u6a5f\u5236\uff0c\u5728\u65bc\u53e3\u670d\u767d\u85dc\u8606\u9187\u9084\u80fd\u9632\u6b62\u4e59\u578b\u6fb1\u7c89\u6a23\u86cb\u767d(beta amyloid)\u5728\u8166\u90e8\u7684\u5806\u7a4d\uff0c\u963b\u65b7\u63a5\u4e0b\u4f86\u8840\u7ba1\u65b0\u751f\uff0c\u6700\u5f8c\u5c0e\u81f4\u963f\u8332\u6d77\u9ed8\u75c7\u5f62\u6210\u7684\u53ef\u80fd\u3002 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fibrosis)\u7684\u529f\u80fd\u3002 (\u56db). \u9632\u764c\u6a5f\u5236 \u5168\u7403\u79d1\u5b78\u5bb6\u91dd\u5c0d\u767d\u85dc\u8606\u9187\u7684\u9810\u9632\u816b\u7624\u6548\u61c9\u505a\u4e86\u4e00\u7cfb\u5217\u5be6\u9a57\uff0c\u5230\u76ee\u524d\u70ba\u6b62\u7684\u975e\u4eba\u9ad4\u5be6\u9a57\u5c55\u73fe\u4e86\u8c50\u78a9\u7684\u6210\u679c\u3002\u5be6\u9a57\u4e2d\u5c07\u767d\u85dc\u8606\u9187\u6ce8\u5c04\u81f3\u5206\u5b50\u5167\uff0c\u8b49\u5be6\u5c0d\u65bc\u4e73\u764c\u3001\u76ae\u819a\u764c\u3001\u80c3\u764c\u3001\u76f4\u8178\u764c\u3001\u98df\u9053\u764c\u3001\u524d\u5217\u817a\u764c\u3001\u80f0\u81df\u764c\u8207\u767d\u8840\u75c5\u7686\u6709\u6b63\u9762\u6548\u61c9\u3002\u6548\u679c\u6700\u4f73\u7684\u662f\u816b\u7624\u5f97\u4ee5\u548c\u767d\u85dc\u8606\u9187\u76f4\u63a5\u63a5\u89f8\u7684\u75c5\u4f8b\uff0c\u5982\u76ae\u819a\u3001\u98df\u9053\u548c\u6d88\u5316\u9053\u7684\u816b\u7624\u90fd\u51fa\u73fe\u6578\u91cf\u548c\u9ad4\u7a4d\u6e1b\u5c11\u7684\u73fe\u8c61\u3002\u53ef\u4ee5\u8aaa\u5728\u816b\u7624\u767c\u5c55\u7684\u5404\u968e\u6bb5\uff0c\u7121\u8ad6\u662f\u8d77\u59cb\u671f(initiation)\u3001\u4fc3\u9032\u671f(promotion)\u3001\u9032\u5c55\u671f(progression)\uff0c\u767d\u85dc\u8606\u9187\u90fd\u80fd\u767c\u63ee\u963b\u65b7\u4f5c\u7528\u3002\u7d30\u80de\u5be6\u9a57\u767c\u73fe\u767d\u85dc\u8606\u9187\u53ef\u5c0d\u65bc\u4e9e\u7d30\u80de\u7cfb\u7d71\u7522\u751f\u85e5\u7406\u4f5c\u7528\uff0c\u53ef\u8abf\u63a7NF-kB\u8f49\u9304\u56e0\u5b50\u3001\u6291\u5236\u7d30\u80de\u8272\u7d20P450\u548c\u540c\u529f\u8122CYP1A1\u3002\u6b64\u5916\u9084\u767c\u73fe\u767d\u85dc\u8606\u9187\u53ef\u4ee5\u6291\u5236\u4eba\u985e\u80f0\u81df\u764c\u7684\u764c\u7d30\u80de\u682a(cell lines)\u64f4\u6563\u4e26\u5177\u6709\u6297\u6c27\u5316\u8207\u6297\u8840\u7ba1\u65b0\u751f(anti-angiogenic)\u7684\u7279\u6027\u3002\u8840\u7ba1\u65b0\u751f\u96d6\u7136\u5728\u4eba\u9ad4\u751f\u9577\u548c\u50b7\u53e3\u7652\u5408\u4e0a\u626e\u6f14\u6b63\u9762\u7684\u89d2\u8272\uff0c\u4f46\u816b\u7624\u5f62\u6210\u6642\u4e5f\u6703\u4fc3\u4f7f\u8840\u7ba1\u65b0\u751f\u904e\u5ea6\u4f5c\u7528\uff0c\u9020\u6210\u764c\u7d30\u80de\u64f4\u6563\uff0c\u6211\u5011\u5728\u963f\u8332\u6d77\u9ed8\u75c7\u7684\u6bb5\u843d\u4ea6\u8a0e\u8ad6\u904e\u8840\u7ba1\u589e\u751f\u7684\u5f0a\u75c5\u3002 \u98df\u7269\u4f86\u6e90 \u96d6\u8aaa\u767d\u85dc\u8606\u9187\u53ea\u6709\u5728\u690d\u7269\u4e0a\u624d\u80fd\u627e\u5230\uff0c\u4f46\u4e5f\u4e0d\u662f\u6bcf\u7a2e\u690d\u7269\u90fd\u6709\u3002\u542b\u91cf\u6700\u8c50\u5bcc\u4f86\u6e90\u5305\u62ec\u8461\u8404\u3001\u8461\u8404\u6c41\u548c\u7d05\u9152\uff0c\u5c24\u5176\u662f\u7d05\u9152\u7684\u542b\u91cf\u6700\u8c50\u5bcc\u3002\u6b64\u5916\u542b\u6709\u767d\u85dc\u8606\u9187\u7684\u53ef\u98df\u7528\u4f86\u6e90\u5c31\u53ea\u6709\u8d8a\u6a58\u5c6c(Vaccinium)\u8393\u679c\u985e\u5982\u85cd\u8393\u3001\u8d8a\u6a58(\u5c71\u6851\u5b50)\u3001\u5c0f\u7d05\u8393\u7b49\u4ee5\u53ca\u82b1\u751f\u3002\u5c31\u8461\u8404\u800c\u8a00\uff0c\u767d\u85dc\u8606\u9187\u53ea\u5b58\u5728\u65bc\u679c\u76ae\u4e2d\uff0c\u800c\u9152\u4e2d\u7684\u767d\u85dc\u8606\u9187\u542b\u91cf\u5c31\u8981\u770b\u8461\u8404\u76ae\u7684\u767c\u9175\u6642\u9593\u591a\u5c11\u800c\u5b9a\uff0c\u4e5f\u5c31\u56e0\u6b64\uff0c\u767d\u9152\u548c\u7c89\u7d05\u9152\u4e2d\u7684\u542b\u91cf\u5c31\u6bd4\u7d05\u9152\u5c11\u3002\u7d05\u8272\u6216\u7d2b\u8272\u8461\u8404\u6c41\u4ea6\u662f\u826f\u597d\u7684\u767d\u85dc\u8606\u9187\u98df\u7269\u4f86\u6e90\u3002\u4e0d\u904e\u8c50\u5bcc\u7684\u767d\u85dc\u8606\u9187\u4e4b\u5916\uff0c\u7d05\u9152\u9084\u542b\u6709\u5176\u4ed6\u7684\u591a\u915a\u985e\uff0c\u6fc3\u5ea6\u751a\u81f3\u6bd4\u767d\u85dc\u8606\u9187\u66f4\u9ad8(\u5982\u985e\u9ec3\u916eflavonoids)\u3002\u4e0b\u8868\u53ef\u898b\u5728\u98f2\u6599\u548c\u98df\u7269\u4e2d\u7684\u767d\u85dc\u8606\u9187\u542b\u91cf\uff1a \u8461\u8404\u9152\u8207\u8461\u8404\u6c41\u7684\u767d\u85dc\u8606\u9187\u7e3d\u542b\u91cf \u98f2\u6599 \u767d\u85dc\u8606\u9187\u7e3d\u542b\u91cf (\u6beb\u514bmg\/\u516c\u5347liter) 5\u76ce\u53f8\u7684\u73bb\u7483\u74f6\u88dd\u4e2d\u767d\u85dc\u8606\u9187\u7e3d\u542b\u91cf (\u6beb\u514bmg) \u767d\u9152 (\u897f\u73ed\u7259\u54c1\u7a2e) 0.05-1.80 0.01-0.27 \u7c89\u7d05\u9152 (\u897f\u73ed\u7259\u54c1\u7a2e) 0.43-3.52 0.06-0.53 \u7d05\u9152 (\u897f\u73ed\u7259\u54c1\u7a2e) 1.92-12.59 0.29-1.89 \u7d05\u9152 (\u5168\u7403\u54c1\u7a2e) 1.98-7.13 0.30-1.07 \u7d05\u8461\u8404\u6c41 (\u897f\u73ed\u7259\u54c1\u7a2e) 1.14-8.69 0.17-1.30 […]<\/p>\n

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