{"id":2085,"date":"2017-03-05T18:50:52","date_gmt":"2017-03-05T23:50:52","guid":{"rendered":"http:\/\/www.deepthinkgohelper.com\/wp\/?p=2085"},"modified":"2022-05-26T01:28:21","modified_gmt":"2022-05-26T01:28:21","slug":"%e5%85%b3%e4%ba%8e%e7%99%bd%e8%97%9c%e8%8a%a6%e9%86%87%e9%92%88%e5%af%b9%e4%b8%80%e4%ba%9b%e7%96%be%e7%97%85%e7%9a%84%e7%a7%91%e5%ad%a6%e5%ae%9e%e9%aa%8c%e6%8a%a5%e5%91%8a","status":"publish","type":"post","link":"http:\/\/johnhealth.blog\/ch\/?p=2085","title":{"rendered":"\u5173\u4e8e\u767d\u85dc\u82a6\u9187\u9488\u5bf9\u4e00\u4e9b\u75be\u75c5\u7684\u79d1\u5b66\u5b9e\u9a8c\u62a5\u544a"},"content":{"rendered":"<h2><strong>\u690d\u7269\u6297\u6bd2\u7d20\u767d\u85dc\u82a6\u9187\u7684\u7814\u7a76\u5f00\u53d1\u8fdb\u5c55<\/strong><\/h2>\n<p>\u4f5c\u8005\uff1a\u5b59\u534e\u5e9a<\/p>\n<p>\u767d\u9ece\u82a6\u9187(resveratrol,\u7b80\u79f0Res)\uff0c\u5b58\u5728\u4e8e\u8461\u8404\u3001\u864e\u6756\u3001\u82b1\u751f\u7b49\u591a\u79cd\u690d\u7269\u4e2d\uff0cRes\u6700\u521d\u662f\u4f5c\u4e3a\u8461\u8404\u5c5e\u690d\u7269\u7684\u690d\u7269\u6297 \u6bd2\u7d20\u800c\u88ab\u53d1\u73b0\uff0c\u968f\u7740\u5bf9Res\u7814\u7a76\u7684\u6df1\u5165\uff0c\u4eba\u4eec\u53d1\u73b0\u5176\u5177\u6709\u6297\u6c27\u5316\u3001\u6297\u764c\u3001\u964d\u8840\u8102\u3001\u9632\u6cbb\u5fc3\u8840\u7ba1\u75be\u75c5\u53ca\u5ef6\u7f13\u8870\u8001\u7b49\u529f\u6548\uff0c\u662f\u5bf9\u4eba\u4f53\u5065\u5eb7\u975e\u5e38\u6709\u76ca\u7684\u4e00\u79cd\u529f\u80fd\u6027\u7269\u8d28\u3002 \u672c\u6587\u5bf9\u767d\u85dc\u82a6\u9187\u7684\u7406\u5316\u6027\u8d28\u3001\u690d\u7269\u6765\u6e90\u3001\u63d0\u53d6\u9014\u5f84\u3001\u5206\u79bb\u7eaf\u5316\u7b49\u5185\u5bb9\u8fdb\u884c\u4e86\u7b80\u8ff0\u3002<\/p>\n<p><a href=\"http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/ConferencePaper_7320843.aspx\" target=\"_blank\" rel=\"noopener\">http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/ConferencePaper_7320843.aspx<\/a><\/p>\n<p>\u201c\u4e07\u65b9\u533b\u5b66\u7f51\u201d\u5173\u4e8e\u201c\u767d\u85dc\u82a6\u9187\u201d\u7684\u5b9e\u9a8c\u62a5\u544a\u67091649\u6761\u73b0\u6458\u5f55\u90e8\u5206\uff1a<\/p>\n<p><strong>\u767d\u85dc\u82a6\u9187\u5bf9\u764c\u7684\u5316\u5b66\u9884\u9632\u4f5c\u7528<\/strong><br \/>\n\u7ed3\u8bba\uff1a\u767d\u85dc\u82a6\u9187\u5728\u764c\u53d1\u751f\u7684\u7a81\u53d8\u3001\u4fc3\u764c\u53ca\u6f14\u8fdb\u5404\u9636\u6bb5\u5747\u53ef\u53d1\u6325\u79ef\u6781\u7684\u5bf9\u6297\u4f5c\u7528.\u4f5c\u4e3a\u764c\u5316\u5b66\u9884\u9632\u5242,\u5177\u6709\u8f83\u597d\u7684\u5f00\u53d1\u5e94\u7528\u524d\u666f.<\/p>\n<p>\u4f5c \u8005\uff1a \u4ed8\u62db\u5a23 \u66f9\u7389 \u738b\u51ef\u98ce \u5f90\u5c11\u950b \u97e9\u9510 (\u5317\u4eac\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662,\u4e2d\u56fd\u534f\u548c\u533b\u79d1\u5927\u5b66,\u836f\u7269\u7814\u7a76\u6240)<\/p>\n<p>\u520a \u540d\uff1a\u300a\u764c\u75c7\u300b\u00a0 2004 \u5e7423\u537708\u671f<\/p>\n<p><a href=\"http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_ez200408002.aspx\" target=\"_blank\" rel=\"noopener\">http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_ez200408002.aspx<\/a><\/p>\n<p><strong>\u690d\u7269\u591a\u915a\u7c7b\u5316\u5408\u7269\u6291\u5236\u4eba\u4e73\u817a\u764cMCF-7\/ADM\u7ec6\u80de\u7684\u7b5b\u9009<\/strong><\/p>\n<p>\u7ed3\u8bba\uff1a\u767d\u85dc\u82a6\u9187\u8054\u5408\u963f\u9709\u7d20\u5bf9\u4eba\u4e73\u817a\u764cMCF-7\/ADM\u7ec6\u80de\u5177\u6709\u6291\u5236\u4f5c\u7528\uff0c\u4e14\u57fa\u672c\u65e0\u6bd2\u5bb3\u4f5c\u7528\u3002<\/p>\n<p>\u4f5c \u8005\uff1a\u9ec4\u82b3\u00a0 \u9ec4\u5b50\u6770\u00a0 \u9648\u6d01\u00a0 \u6c6a\u5bb6\u68a8 (\u798f\u5efa\u533b\u79d1\u5927\u5b66\u516c\u5171\u536b\u751f\u5b66\u9662\u8425\u517b\u4e0e\u4fdd\u5065\u533b\u5b66\u7cfb)<br \/>\n\u520a \u540d\uff1a\u5b9e\u7528\u80bf\u7624\u6742\u5fd7\u00a0\u00a0 2009 \u5e7424\u537702\u671f<br \/>\n<a href=\"http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_syzlzz200902009.aspx\" target=\"_blank\" rel=\"noopener\">http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_syzlzz200902009.aspx<\/a><\/p>\n<p><strong>\u767d\u85dc\u82a6\u9187\u8bf1\u5bfcHO-1\u5bf9\u9152\u7cbe\u6027\u809d\u7ec6\u80de\u7684\u4fdd\u62a4\u4f5c\u7528<\/strong><br \/>\n\u7ed3\u8bba\uff1a\u767d\u85dc\u82a6\u9187\u5bf9\u9152\u7cbe\u5bfc\u81f4\u7684\u4eba\u809d\u7ec6\u80de\u635f\u4f24\u5177\u6709\u4fdd\u62a4\u4f5c\u7528,\u8fd9\u79cd\u4fdd\u62a4\u4f5c\u7528\u4e0e\u5176\u8bf1\u5bfc\u7684HO-1\u9176\u6d3b\u6027\u5347\u9ad8\u6709\u5173\u3002<br \/>\n\u4f5c \u8005\uff1a\u5510\u7389\u6db5 \u8f9b\u9e4f \u90dd\u4e3d\u840d \u59da\u5e73 \u5218\u70c8\u521a \u5b59\u79c0\u53d1(\u534e\u4e2d\u79d1\u6280\u5927\u5b66\u540c\u6d4e\u533b\u5b66\u9662\u516c\u5171\u536b\u751f\u5b66\u9662)<\/p>\n<p>\u520a \u540d\uff1a\u8425\u517b\u5b66\u62a5\u00a0\u00a0 2011 \u5e7433\u537701\u671f<\/p>\n<p><a href=\"http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_yingyxb201101011.aspx\" target=\"_blank\" rel=\"noopener\">http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_yingyxb201101011.aspx<\/a><\/p>\n<p><strong>\u767d\u9ece\u82a6\u9187\u5bf9\u809d\u7ea4\u7ef4\u5316\u5927\u9f20\u809d\u7ec4\u7ec7E-\u9499\u7c98\u9644\u7d20\u8868\u8fbe\u7684\u5e72\u9884\u4f5c\u7528<\/strong><\/p>\n<p>\u7ed3\u8bba\uff1aE-\u9499\u7c98\u9644\u7d20\u5728\u4e0d\u540c\u9636\u6bb5\u809d\u7ea4\u7ef4\u5316\u5927\u9f20\u809d\u7ec4\u7ec7\u5747\u6709\u8868\u8fbe,\u4e14\u968f\u7740\u7ea4\u7ef4\u5316\u7a0b\u5ea6\u7684\u52a0\u91cd\u800c\u8868\u8fbe\u589e\u5f3a.\u767d\u9ece\u82a6\u9187\u53ef\u4ee5\u660e\u663e\u6539\u5584\u5927\u9f20\u809d\u7ea4\u7ef4\u5316\u7a0b\u5ea6,\u5e76\u51cf\u5c11E-\u9499\u7c98\u9644\u7d20 mRNA\u6c34\u5e73.<\/p>\n<p>\u4f5c \u8005\uff1a\u00a0\u00a0 \u4e07\u8363. \u4f0d\u5efa\u4e1a. \u5218\u73fa.\u6743\u9e64\u9e23.\u725b\u57f9\u52e4.\u738b\u5174\u9e4f.\u90ed\u4f20\u52c7(\u4e0a\u6d77\u540c\u6d4e\u5927\u5b66\u9644\u5c5e\u7b2c\u5341\u4eba\u6c11\u533b\u9662\u6d88\u5316\u79d1)<\/p>\n<p>\u520a \u540d\uff1a\u300a\u5b9e\u7528\u809d\u810f\u75c5\u6742\u5fd7\u300b\u00a0\u00a0 2009 \u5e7412\u537705\u671f<\/p>\n<p><a href=\"http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_sygzbzz200905004.aspx\" target=\"_blank\" rel=\"noopener\">http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_sygzbzz200905004.aspx<\/a><\/p>\n<p><strong>\u767d\u85dc\u82a6\u9187\u5bf9\u809d\u764c\u7ec6\u80de\u57fa\u8d28\u91d1\u5c5e\u86cb\u767d\u9176-9\u8868\u8fbe\u7684\u5f71\u54cd<\/strong><\/p>\n<p>\u7ed3\u8bba\uff1a\u767d\u85dc\u82a6\u9187\u5bf9\u809d\u764c\u7ec6\u80de\u7684\u751f\u957f\u5177\u6709\u6291\u5236\u4f5c\u7528,\u4e14\u80fd\u4e0b\u8c03\u5176MMP-9\u7684\u8868\u8fbe,\u53ef\u80fd\u5177\u6709\u6291\u5236\u809d\u764c\u7ec6\u80de\u4fb5 \u88ad\u8f6c\u79fb\u7684\u4f5c\u7528\u3002<\/p>\n<p>\u4f5c \u8005\uff1a\u4f59\u6d77\u6ce2 \u6f58\u627f\u6069 \u5434\u6b66\u519b\u00a0 \u8d75\u56db\u6d77\u00a0 \u5f20\u6167\u5cf0(\u6cb3\u5357\u7701\u4eba\u6c11\u533b\u9662\u91cd\u75c7\u76d1\u62a4\u6cbb\u7597\u4e2d\u5fc3)<\/p>\n<p>\u520a \u540d\uff1a\u4e2d\u897f\u533b\u7ed3\u5408\u5b66\u62a5\u00a0 2008 \u5e746\u537703\u671f<\/p>\n<p><a href=\"http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_zxyjhxb200803010.aspx\" target=\"_blank\" rel=\"noopener\">http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_zxyjhxb200803010.aspx<\/a><\/p>\n<p><strong>\u767d\u85dc\u82a6\u9187\u5bf9\u5c0f\u9f20\u6162\u6027\u75c5\u6bd2\u6027\u5fc3\u808c\u708e\u5fc3\u808c\u7ea4\u7ef4\u5316\u7684\u5e72\u9884\u4f5c\u7528<\/strong><\/p>\n<p>\u7ed3\u8bba\uff1aVMC\u6162\u6027\u671f\u5c0f\u9f20\u6a21\u578b\u4e0a,\u767d\u85dc\u82a6\u9187\u80fd\u6291\u5236VMC\u5fc3\u808c\u80f6\u539f\u7684\u589e\u751f,\u5177\u6709\u6297\u5fc3\u808c\u7ea4\u7ef4\u5316\u7684\u4f5c\u7528.<\/p>\n<p>\u4f5c \u8005\uff1a\u6c6a\u5468\u5e73 \u534e\u76ca\u6c11 \u5f20\u5174 \u738b\u4e00\u658c \u77f3\u6653\u9752 \u674e\u660e\u8fdc(\u56db\u5ddd\u5927\u5b66\u534e\u897f\u57fa\u7840\u533b\u5b66\u4e0e\u6cd5\u533b\u5b66\u9662\u5fae\u751f\u7269\u6559\u7814\u5ba4)<\/p>\n<p>\u520a \u540d\uff1a\u4e2d\u56fd\u5f53\u4ee3\u513f\u79d1\u6742\u5fd7\u00a0 2009 \u5e7411\u537704\u671f<\/p>\n<p><a href=\"http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_zgddekzz200904013.aspx\" target=\"_blank\" rel=\"noopener\">http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_zgddekzz200904013.aspx<\/a><br \/>\n<strong>\u767d\u85dc\u82a6\u9187\u5bf9\u5bab\u9888\u764cHeLa\u7ec6\u80de\u57fa\u8d28\u91d1\u5c5e\u86cb\u767d\u9176\u53ca\u5176\u7ec4\u7ec7\u6291\u5236\u5242\u7684\u5f71\u54cd<\/strong><\/p>\n<p>\u7ed3\u8bba\uff1a\u767d\u85dc\u82a6\u9187\u80fd\u6709\u6548\u6291\u5236\u5bab\u9888\u764c\u4fb5\u88ad\u548c\u8f6c\u79fb.<\/p>\n<p>\u4f5c \u8005\uff1a\u8463\u5fb7\u521a \u90ed\u6069\u7ef5 \u5f20\u7476\u00a0 \u9c81\u8273\u660e \u5f20\u6dd1\u5170(\u4e2d\u56fd\u6c88\u9633\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u76db\u4eac\u533b\u9662\u5987\u4ea7\u79d1)<\/p>\n<p>\u520a \u540d\uff1a\u4e2d\u534e\u80bf\u7624\u9632\u6cbb\u6742\u5fd7\u00a0 2007 \u5e7414\u537707\u671f<\/p>\n<p><a href=\"http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_qlzlzz200707003.aspx\" target=\"_blank\" rel=\"noopener\">http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_qlzlzz200707003.aspx<\/a><\/p>\n<p><strong>\u767d\u85dc\u82a6\u9187\u5bf9\u5154\u52a8\u8109\u7ca5\u6837\u786c\u5316\u57fa\u8d28\u91d1\u5c5e\u86cb\u767d\u9176\u8868\u8fbe\u7684\u5f71\u54cd<\/strong><br \/>\n\u7ed3\u8bba\uff1a\u767d\u85dc\u82a6\u9187\u80fd\u591f\u964d\u4f4eMMP-1\u30019\u7684\u6d53\u5ea6,\u4ece\u800c\u9884\u9632\u548c\u5ef6\u7f13\u52a8\u8109\u786c\u5316\u7684\u53d1\u751f.<\/p>\n<p>\u4f5c \u8005\uff1a\u674e\u8fd0\u7530 \u67f3\u6768\u00a0 \u675c\u5927\u52c7 \u738b\u82b3(\u5317\u4eac\u89e3\u653e\u519b\u7b2c305\u533b\u9662,\u5168\u519b\u51a0\u5fc3\u75db\u8bca\u7597\u4e2d\u5fc3)<\/p>\n<p>\u520a \u540d\uff1a\u519b\u533b\u8fdb\u4fee\u5b66\u9662\u5b66\u62a5\u00a0 2010 \u5e7431\u537704\u671f<\/p>\n<p><a href=\"http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_jyjxxyxb201004027.aspx\" target=\"_blank\" rel=\"noopener\">http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_jyjxxyxb201004027.aspx<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-17278\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2017\/03\/Screenshot-1001.png\" alt=\"\" width=\"1920\" height=\"1080\" srcset=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2017\/03\/Screenshot-1001.png 1920w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2017\/03\/Screenshot-1001-300x169.png 300w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2017\/03\/Screenshot-1001-1024x576.png 1024w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2017\/03\/Screenshot-1001-768x432.png 768w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2017\/03\/Screenshot-1001-1536x864.png 1536w\" sizes=\"auto, (max-width: 1920px) 100vw, 1920px\" \/><\/p>\n<p><strong>\u767d\u85dc\u82a6\u9187\u5bf9\u4eba\u6dcb\u5df4\u7624Raji\u7ec6\u80de\u4f53\u5916\u589e\u6b96\u7684\u5f71\u54cd\u5173\u4e8e\u767d\u85dc\u82a6\u9187\u9488\u5bf9\u4e00\u4e9b\u75be\u75c5\u7684\u79d1\u5b66\u5b9e\u9a8c\u62a5\u544a<\/strong><\/p>\n<p>\u7ed3\u8bba\uff1a\u767d\u85dc\u82a6\u9187\u5bf9\u4f53\u5916\u4eba\u6dcb\u5df4\u7624Raji\u7ec6\u80de\u7684\u589e\u6b96\u6709\u6291\u5236\u4f5c\u7528,\u5e76\u53ef\u80fd\u901a\u8fc7\u7ebf\u7c92\u4f53\u9014\u5f84\u4fc3\u8fdb\u5176\u51cb\u4ea1\u3002<\/p>\n<p>\u4f5c \u8005\uff1a\u4e01\u6167\u654f(\u6e56\u5357\u7701\u4eba\u6c11\u533b\u9662\u836f\u5b66\u90e8,\u957f\u6c99,410002) \uff1b \u8d75\u5efa(\u6e56\u5357\u7701\u957f\u6c99\u4eba\u6c11\u533b\u9662\u836f\u5b66\u90e8)<\/p>\n<p>\u520a \u540d\uff1a\u300a\u300b\u00a0 2010 \u5e7412\u537705\u671f<\/p>\n<p><strong>\u767d\u85dc\u82a6\u9187\u6cbb\u75972\u578b\u7cd6\u5c3f\u75c5\u5408\u5e76\u9ad8\u8840\u8102\u75c7\u7684\u4e34\u5e8a\u89c2\u5bdf <\/strong><\/p>\n<p>\u7ed3\u8bba\uff1a\u767d\u85dc\u82a6\u9187\u53ef\u4ee5\u6709\u6548\u63a7\u52362\u578b\u7cd6\u5c3f\u75c5\u5408\u5e76\u9ad8\u8840\u8102\u75c7\u60a3\u8005\u8840\u8102\u6c34\u5e73,\u5e76\u80fd\u589e\u5f3a\u964d\u7cd6\u836f\u7269\u7684\u7597\u6548\u3002<br \/>\n\u4f5c \u8005\uff1a\u859b\u78ca \u82cf\u4e1c\u6708 \u5e9e\u59a9\u71d5(\u6cb3\u5357\u5927\u5b66\u6dee\u6cb3\u533b\u9662\u5185\u5206\u6ccc\u79d1)<\/p>\n<p>&nbsp;<\/p>\n<p>\u520a \u540d:\u300a\u4e2d\u56fd\u533b\u7597\u524d\u6cbf\u300b2011\u5e7407\u671f<\/p>\n<p><strong>\u529f\u80fd\u6027\u98df\u54c1\u914d\u6599\u767d\u85dc\u82a6\u9187\u7684\u5408\u6210\u7814\u7a76<\/strong><\/p>\n<p>\u767d\u85dc\u82a6\u9187\u5177\u6709\u660e\u663e\u7684\u6297\u8840\u5c0f\u677f\u51dd\u805a\u3001\u6297\u6c27\u5316\u3001\u6297\u81ea\u7531\u57fa\u3001\u6297\u83cc\u3001\u6297\u764c\u3001\u964d\u8840\u8102\u3001\u5ef6\u7f13\u4eba\u4f53\u673a\u80fd\u8870\u8001\u3001\u9884\u9632\u5fc3\u8111\u8840\u7ba1\u75be\u75c5\u548c\u96cc\u6fc0\u7d20\u4f5c\u7528\u7b49\u591a\u79cd\u836f\u7406\u4f5c\u7528\uff0c\u53ef\u5e7f\u6cdb\u5e94\u7528\u4e8e\u836f\u7269\u3001\u4fdd\u5065\u54c1\u3001\u98df\u54c1\u548c\u5316\u5986\u54c1\u7b49\u9886\u57df\u3002\u767d\u85dc\u82a6\u9187\u7528\u9014\u5e7f\u6cdb\uff0c\u4f46\u5236\u5907\u6bd4\u8f83\u6602\u8d35\u3002<\/p>\n<p>\u4f5c \u8005\uff1a\u4e01\u5218\u521a\uff08\u66a8\u5357\u5927\u5b66\uff09<\/p>\n<p><a href=\"http:\/\/cdmd.cnki.com.cn\/Article\/CDMD-10559-2007191277.htm\" target=\"_blank\" rel=\"noopener\">http:\/\/cdmd.cnki.com.cn\/Article\/CDMD-10559-2007191277.htm<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-17279\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2017\/03\/Screenshot-1002.png\" alt=\"\" width=\"1920\" height=\"1080\" srcset=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2017\/03\/Screenshot-1002.png 1920w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2017\/03\/Screenshot-1002-300x169.png 300w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2017\/03\/Screenshot-1002-1024x576.png 1024w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2017\/03\/Screenshot-1002-768x432.png 768w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2017\/03\/Screenshot-1002-1536x864.png 1536w\" sizes=\"auto, (max-width: 1920px) 100vw, 1920px\" \/><\/p>\n<p><strong>\u767d\u85dc\u82a6\u9187\u751f\u7269\u5b66\u4f5c\u7528\u53ca\u5176\u5728\u6297\u8fd0\u52a8\u6027\u75b2\u52b3\u4e2d\u7684\u5e94\u7528\u524d\u666f<\/strong><\/p>\n<p>\u767d\u85dc\u82a6\u9187\u5728\u4f53\u5185\u5916\u90fd\u5177\u6709\u5f3a\u5927\u7684\u6297\u6c27\u5316\u4f5c\u7528,\u5176\u5bf9\u5fc3\u8840\u7ba1\u548c\u795e\u7ecf\u7cfb\u7edf\u7684\u4fdd\u62a4\u4f5c\u7528\u548c\u6297\u764c\u4f5c\u7528\u5c24\u4e3a\u7a81\u51fa;\u767d\u85dc\u82a6\u9187\u5bf9\u673a\u4f53\u7279\u5f02\u6027\u514d\u75ab\u548c\u975e\u7279\u5f02\u6027\u514d\u75ab\u529f\u80fd\u90fd\u5177\u6709\u8c03\u8282\u529f\u80fd;\u5927\u5f3a\u5ea6\u8fd0\u52a8\u8bad\u7ec3\u5f15\u8d77\u673a\u4f53\u7ec4\u7ec7\u6c27\u5316\u635f\u4f24\u548c\u514d\u75ab\u529f\u80fd\u964d\u4f4e\u662f\u5bfc\u81f4\u8fd0\u52a8\u6027\u75b2\u52b3\u7684\u91cd\u8981\u56e0\u7d20.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u7ed3\u8bba: \u767d\u85dc\u82a6\u9187\u5728\u6297\u8fd0\u52a8\u6027\u75b2\u52b3\u4e2d\u7684\u5e94\u7528\u5177\u6709\u91cd\u8981\u610f\u4e49.<\/p>\n<p>\u4f5c \u8005\uff1a\u5218\u8273 \u9ec4\u5143\u6c5b \u590f\u5fd7(\u6e56\u5317\u6b66\u6c49\u5e02\u5927\u5b66\u4f53\u80b2\u5b66\u9662\u8fd0\u52a8\u4eba\u4f53\u79d1\u5b66\u7cfb)<\/p>\n<p>\u520a \u540d\uff1a\u300a\u4e2d\u56fd\u4e34\u5e8a\u5eb7\u590d \u300b\u00a0 2006 \u5e7410\u537719\u671f<\/p>\n<p><a href=\"http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_xdkf200619063.aspx\" target=\"_blank\" rel=\"noopener\">http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_xdkf200619063.aspx<\/a><\/p>\n<p><strong>\u767d\u85dc\u82a6\u9187\u6291\u5236\u80f6\u8d28\u7624\u7ec6\u80de\u589e\u6b96\u7684\u4f53\u5185\u5916\u5b9e\u9a8c\u7814\u7a76<\/strong><\/p>\n<p>\u7ed3\u8bba\uff1a\u767d\u85dc\u82a6\u9187(Res)\u53ef\u6291\u5236\u80f6\u8d28\u7624\u7ec6\u80de\u589e\u6b96,\u5ef6\u957f\u8377\u7624\u52a8\u7269\u751f\u5b58\u671f,\u5177\u6709\u6f5c\u5728\u4e34\u5e8a\u5e94\u7528\u4ef7\u503c.<\/p>\n<p>\u4f5c \u8005\uff1a\u738b\u5e7f\u79c0\u00a0 \u6d66\u4f69\u7389\u00a0 \u5eb7\u6625\u751f\u00a0 \u8d3e\u5fd7\u51e1\u00a0 \u5f20\u5fd7\u52c7\u00a0 \u88d8\u660e\u54f2 (\u5929\u6d25\u533b\u79d1\u5927\u5b66\u603b\u533b\u9662\u795e\u7ecf\u5916\u79d1) \uff1b<\/p>\n<p>\u520a \u540d\uff1a\u56fd\u9645\u80bf\u7624\u5b66\u6742\u5fd7\u00a0\u00a0 2006 \u5e7433\u537710\u671f<\/p>\n<p><strong>\u767d\u85dc\u82a6\u9187\u5bf9\u52a8\u8109\u7ca5\u6837\u786c\u5316\u5154\u5fc3\u808c\u7ea4\u7ef4\u5316\u548c\u57fa\u8d28\u91d1\u5c5e\u86cb\u767d\u91762\u3001\u7ec4\u7ec7\u578b\u57fa\u8d28\u91d1\u5c5e\u86cb\u767d\u9176\u6291\u5236\u52422\u8868\u8fbe\u7684\u5f71\u54cd<\/strong><\/p>\n<p>\u7ed3\u8bba\uff1a\u52a8\u8109\u7ca5\u6837\u786c\u5316\u8fdb\u7a0b\u4e2d,\u5b58\u5728\u7740\u5fc3\u808c\u7ea4\u7ef4\u5316\u3001\u57fa\u8d28\u91d1\u5c5e\u86cb\u767d\u91762\u8868\u8fbe\u589e\u591a\u548c\u7ec4\u7ec7\u578b\u57fa\u8d28\u91d1\u5c5e\u86cb\u767d\u9176\u6291\u5236\u52422\u8868\u8fbe\u51cf\u5c11\u7b49\u73b0\u8c61,\u767d\u85dc\u82a6\u9187\u80fd\u51cf\u8f7b\u57fa\u8d28\u91d1\u5c5e\u86cb\u767d\u91762\/\u7ec4\u7ec7 \u578b\u57fa\u8d28\u91d1\u5c5e\u86cb\u767d\u9176\u6291\u5236\u52422\u8868\u8fbe\u7684\u5931\u8861,\u6539\u5584\u5fc3\u808c\u7ea4\u7ef4\u5316.<\/p>\n<p>\u4f5c \u8005\uff1a\u9ad8\u6dd1\u537f\u00a0 \u6731\u9e4f\u7acb (\u798f\u5efa\u533b\u79d1\u5927\u5b66\u7701\u7acb\u4e34\u5e8a\u533b\u5b66\u9662\u4e8c\u5185\u79d1, )<\/p>\n<p>\u520a \u540d\uff1a\u4e2d\u56fd\u52a8\u8109\u786c\u5316\u6742\u5fd7\u00a0\u00a0 2009 \u5e7417\u537702\u671f<\/p>\n<p><strong>\u767d\u85dc\u82a6\u9187\u5728\u7ea4\u7ef4\u589e\u751f\u6027\u75be\u75c5\u4e2d\u7684\u4f5c\u7528\u673a\u5236\u7814\u7a76\u8fdb\u5c55<\/strong><\/p>\n<p>&lt;\u7bc7\u9996&gt; \u7ea4\u7ef4\u589e\u751f\u6027\u75be\u75c5\u5982\u809d\u7ea4\u7ef4\u5316\u3001\u5fc3\u808c\u7ea4\u7ef4\u5316\u3001\u80be\u7ea4\u7ef4\u5316\u3001\u80ba\u7ea4\u7ef4\u5316\u3001\u795e\u7ecf\u7cfb\u7edf\u7ea4\u7ef4\u5316\u75c5\u53d8\u3001\u589e\u751f\u6027\u7622\u75d5\u7b49\u5728\u4e34\u5e8a\u4e0a\u6bd4\u8f83\u5e38\u89c1,\u5176\u53d1\u75c5\u56e0\u7d20\u548c\u4e34\u5e8a\u8868\u73b0\u5404\u4e0d\u76f8\u540c,\u4f46\u5b83\u4eec \u6700\u7ec8\u7684\u75c5\u7406\u7279\u5f81\u662f\u7ec6\u80de\u5916\u57fa\u8d28\u5728\u7ec4\u7ec7\u5668\u5b98\u5185\u8fc7\u5ea6\u6c89\u79ef\u6240\u81f4\u7684\u7ea4\u7ef4\u5316,\u662f\u8bb8\u591a\u75be\u75c5\u81f4\u6b8b\u3001\u81f4\u6b7b\u7684\u4e3b\u8981\u539f\u56e0.\u4ee4\u4eba\u9057\u61be\u7684\u662f,\u76ee\u524d\u5e7f\u6cdb\u7528\u4e8e\u6cbb\u7597\u5404\u79cd\u7ea4\u7ef4\u5316\u75be\u75c5\u7684\u836f\u7269\u90fd \u4e0d\u80fd\u6709\u6548\u5730\u963b\u6b62\u7ea4\u7ef4\u5316\u7684\u53d1\u5c55,\u66f4\u4e0d\u80fd\u964d\u4f4e\u7ea4\u7ef4\u5316\u75be\u75c5\u75c5\u6b7b\u7387.<\/p>\n<p>\u4f5c \u8005\uff1a\u738b\u5728\u5ca9 \u5f20\u5e73(\u5357\u534e\u5927\u5b66\u9644\u5c5e\u7b2c\u4e00\u533b\u9662\u547c\u5438\u5185\u79d1,\u8861\u9633,421001) \uff1b<\/p>\n<p>\u520a \u540d\uff1a\u533b\u5b66\u7814\u7a76\u6742\u5fd7\u00a0 2010 \u5e7439\u537705\u671f<\/p>\n<p><a href=\"http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_yxyjtx201005040.aspx\" target=\"_blank\" rel=\"noopener\">http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_yxyjtx201005040.aspx<\/a><\/p>\n<p><strong>\u767d\u85dc\u82a6\u9187\u5bf9\u4eba\u80ba\u817a\u764cA549\u7ec6\u80de\u5468\u671f\u7684\u5f71\u54cd\u53ca\u5176\u673a\u5236\u7814\u7a76<\/strong><\/p>\n<p>\u7ed3\u8bba:\u767d\u85dc\u82a6\u9187\u80fd\u660e\u663e\u6291\u5236\u4eba\u80ba\u817a\u764cA549\u7ec6\u80de\u7684\u589e\u6b96.\u767d\u85dc\u82a6\u9187\u53ef\u901a\u8fc7\u8c03\u8282\u7ec6\u80de\u5468\u671f\u86cb\u767dcyclin D1\u3001p21cip1\u7684\u8868\u8fbe\u8c03\u63a7\u7ec6\u80de\u5468\u671f\u8fdb\u7a0b,\u6291\u5236\u7ec6\u80de\u589e\u6b96.<\/p>\n<p>\u4f5c \u8005\uff1a\u9648\u52a0\u987a \u5415\u4fca\u660e \u675f\u6c38\u524d (\u6c5f\u82cf\u7701\u4eba\u6c11\u533b\u9662\u80bf\u7624\u4e2d\u5fc3)<\/p>\n<p>\u520a \u540d\uff1a\u4e34\u5e8a\u80bf\u7624\u5b66\u6742\u5fd7\u00a0\u00a0 2011 \u5e7416\u537706\u671f<\/p>\n<p><a href=\"http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_lczlxzz201106006.aspx\" target=\"_blank\" rel=\"noopener\">http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_lczlxzz201106006.aspx<\/a><\/p>\n<p><strong>\u767d\u85dc\u82a6\u9187\u5bf9\u4eba\u80f0\u817a\u764cPANC-1\u7ec6\u80de\u589e\u6b96\u4e0e\u4fb5\u88ad\u7684\u5f71\u54cd<\/strong><\/p>\n<p>\u7ed3\u8bba:\u767d\u85dc\u82a6\u9187\u53ef\u660e\u663e\u6291\u5236\u80f0\u817a\u764cPANC-1\u7ec6\u80de\u589e\u6b96,\u8bf1\u5bfc\u7ec6\u80de\u51cb\u4ea1\u5e76\u6291\u5236\u5176\u4fb5\u88ad\u80fd\u529b.<\/p>\n<p>\u4f5c \u8005\uff1a\u5d14\u9759\u00a0 \u8d75\u521a \u52fe\u5584\u6dfc \u4fde\u8273\u840d \u738b\u6625\u53cb(\u534e\u4e2d\u79d1\u6280\u5927\u5b66\u540c\u6d4e\u533b\u5b66\u9662\u9644\u5c5e\u534f\u548c\u533b\u9662\u80f0\u817a\u5916\u79d1\u4e2d\u5fc3)<\/p>\n<p>\u520a \u540d\uff1a\u4e2d\u534e\u6d88\u5316\u5916\u79d1\u6742\u5fd7\u00a0 2010 \u5e7409\u537705\u671f<\/p>\n<p><strong>\u767d\u85dc\u82a6\u9187\u5728\u8bf1\u5bfc\u4eba\u80c3\u764cHGC27\u7ec6\u80de\u51cb\u4ea1\u4e2d\u7684\u673a\u5236\u7814\u7a76<\/strong><\/p>\n<p>\u7ed3\u8bba\uff1a\u767d\u85dc\u82a6\u9187(Res)\u80fd\u591f\u6291\u5236\u4eba\u80c3\u764cHGC27\u7ec6\u80de\u7684\u589e\u6b96.\u5e76\u4e14\u8bf1\u5bfc\u5176\u51cb\u4ea1,\u5176\u673a\u5236\u53ef\u80fd\u4e0e\u4e0a\u8c03PTEN\u7684\u8868\u8fbe\u548c\u6291\u5236Akt\u7684\u78f7\u9178\u5316\u6709\u5173,\u5e76\u901a\u8fc7\u8c03\u63a7VEGF\u548cMMP-9 \u7684\u5206\u6ccc\u5b9e\u73b0HGC27\u7684\u589e\u6b96\u6291\u5236\u53ca\u51cb\u4ea1.<\/p>\n<p>\u4f5c \u8005\uff1a\u6768\u5b8f\u6885 \u90a2\u5f71 \u90d1\u7f8e\u73cd(\u8fbd\u5b81\u7701\u80bf\u7624\u533b\u9662\u5185\u79d1)<\/p>\n<p>\u520a \u540d\uff1a\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u5b66\u62a5\uff08\u533b\u5b66\u7248\uff09\u00a0 2011 \u5e7431\u537702\u671f<\/p>\n<p><a href=\"http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_shdeykdxxb201102015.aspx\" target=\"_blank\" rel=\"noopener\">http:\/\/so.med.wanfangdata.com.cn\/ViewHTML\/PeriodicalPaper_shdeykdxxb201102015.aspx<\/a><\/p>\n<p><strong>\u767d\u85dc\u82a6\u9187\u5bf9\u80f6\u539f\u8bf1\u5bfc\u5927\u9f20\u5173\u8282\u708e\u7684\u6297\u708e\u4f5c\u7528\u7814\u7a76<\/strong><\/p>\n<p>\u7ed3\u8bba :\u2460\u9ad8\u3001\u4e2d\u5242\u91cf\u767d\u85dc\u82a6\u9187\u80fd\u591f\u7f13\u89e3CIA\u7684\u708e\u75c7\u75c7\u72b6,\u800c\u4f4e\u5242\u91cf\u767d\u85dc\u82a6\u9187\u5219\u65e0\u6b64\u4f5c\u7528.\u2461\u4e2d\u7b49\u5242\u91cf\u767d\u85dc\u82a6\u9187\u5bf9CIA\u5927\u9f20\u7684\u77ed\u671f\u7597\u6548\u4e0eTGP\u76f8\u5f53,\u9ad8\u5242\u91cf\u767d\u85dc\u82a6\u9187\u7684 \u7597\u6548\u5f3a\u4e8eTGP,\u4f46\u5f31\u4e8eLEF.\u2462\u767d\u85dc\u82a6\u9187\u80fd\u591f\u6291\u5236\u8840\u6e05\u6297C\u2161\u6297\u4f53\u7684\u751f\u6210.<\/p>\n<p>\u4f5c \u8005\uff1a\u675c\u91d1\u70fd \u674e\u82ac \u7530\u9759 \u8c22\u5e0c \u9648\u8fdb\u4f1f 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