{"id":20182,"date":"2023-05-18T03:54:01","date_gmt":"2023-05-18T03:54:01","guid":{"rendered":"http:\/\/johnhealth.blog\/ch\/?p=20182"},"modified":"2023-05-18T03:54:01","modified_gmt":"2023-05-18T03:54:01","slug":"nmn%e5%8f%af%e4%bf%9d%e6%8a%a4%e5%8d%b5%e6%af%8d%e7%bb%86%e8%83%9e-%e6%94%b9%e5%96%84%e7%94%9f%e8%82%b2%e8%83%bd%e5%8a%9b","status":"publish","type":"post","link":"http:\/\/johnhealth.blog\/ch\/?p=20182","title":{"rendered":"NMN\u53ef\u4fdd\u62a4\u5375\u6bcd\u7ec6\u80de , \u6539\u5584\u751f\u80b2\u80fd\u529b"},"content":{"rendered":"<p>NMN\u53ef\u4fdd\u62a4\u5375\u6bcd\u7ec6\u80de &#8211; \u6539\u5584\u751f\u80b2\u80fd\u529b<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-20183\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/05\/\u73af\u5883.jpg\" alt=\"\" width=\"960\" height=\"640\" srcset=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/05\/\u73af\u5883.jpg 960w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/05\/\u73af\u5883-300x200.jpg 300w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/05\/\u73af\u5883-768x512.jpg 768w\" sizes=\"auto, (max-width: 960px) 100vw, 960px\" \/> <img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-large wp-image-20185\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/05\/\u73af\u58833.jpg\" alt=\"\" width=\"704\" height=\"678\" srcset=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/05\/\u73af\u58833.jpg 704w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/05\/\u73af\u58833-300x289.jpg 300w\" sizes=\"auto, (max-width: 704px) 100vw, 704px\" \/><\/p>\n<p>\u8d8a\u6765\u8d8a\u4e25\u91cd\u7684\u73af\u5883\u6c61\u67d3\uff0c\u4e0d\u4ec5\u5f71\u54cd\u7740\u4eba\u4eec\u7684\u5c45\u4f4f\u73af\u5883\uff0c\u4e5f\u5728\u635f\u5bb3\u7740\u4eba\u4eec\u7684\u751f\u80b2\u80fd\u529b\u3002<br \/>\n\u800c\u8bb8\u591a\u5f71\u54cd\u751f\u6b96\u529f\u80fd\u7684\u7269\u8d28\uff0c\u5c31\u4e0d\u4ec5\u51fa\u73b0\u4e86\u5de5\u4e1a\u5236\u9020\u4e0a\uff0c\u4e5f\u9891\u7e41\u51fa\u73b0\u5728\u6211\u4eec\u5e38\u89c1\u7684\u5bb6\u5ead\u7269\u54c1\u4e2d\u3002<\/p>\n<p>\u25b2 \u73af\u5883\u6c61\u67d3\u6240\u5bfc\u81f4\u7684\u751f\u80b2\u95ee\u9898\u5f15\u8d77\u4e86\u4eba\u4eec\u7684\u5173\u6ce8\u3002<br \/>\n\u4e59\u4e8c\u9187\u4e01\u919a\uff08EGBE\uff09\uff0c\u5c31\u662f\u4e00\u79cd\u751f\u6d3b\u4e2d\u5e38\u89c1\u7684\u300c\u751f\u6b96\u6bd2\u7d20\u300d\u3002\u5b83\u53ef\u71c3\uff0c\u6709\u6bd2\uff0c\u5177\u523a\u6fc0\u6027\u3002\u5370\u5237\u6cb9\u58a8\u4e36\u5370\u7ae0\u6cb9\u58a8\u4e36\u5899\u58c1\u6d82\u6599\u4e36\u55b7\u6f06\u7b49\uff0c\u4e3b\u8981\u6210\u5206\u90fd\u662f\u4e59\u4e8c\u9187\u4e01\u919a\u3002<br \/>\n\u5b83\u4f1a\u5f71\u54cd\u6210\u5e74\u7537\u6027\u4e36\u5973\u6027\u7684\u6027\u529f\u80fd\u548c\u751f\u80b2\u80fd\u529b\uff0c\u5e72\u6270\u6b63\u5e38\u751f\u6b96\uff0c\u5bf9\u5f8c\u4ee3\u4f1a\u9020\u6210\u5148\u5929\u7f3a\u9677\uff0c\u751a\u81f3\u662f\u80da\u80ce\u6b7b\u4ea1\u7b49\u4e0d\u5229\u5f71\u54cd\u3002<\/p>\n<p>\u25b2 \u4e59\u4e8c\u9187\u4e01\u919a\u5e38\u7528\u65bc\u5de5\u4e1a\u548c\u5bb6\u5ead\u4ea7\u54c1\u7684\u5236\u9020\u3002<br \/>\n\u5357\u4eac\u519c\u4e1a\u5927\u5b66\u5728\u300aFrontiers in Cell and Developmental Biology\u300b\u4e0a\u53d1\u8868\u6587\u7ae0\uff0c\u53d1\u73b0\u4e59\u4e8c\u9187\u4e01\u919a\u66b4\u9732\uff0c\u5bfc\u81f4\u5375\u6bcd\u7ec6\u80de\u79ef\u805a\u6709\u5bb3\u7684\u542b\u6c27\u5206\u5b50\u6d3b\u6027\u6c27\uff08ROS\uff09\u548cDNA\u635f\u4f24\uff0c\u4ece\u800c\u5bfc\u81f4\u5375\u6bcd\u7ec6\u80de\u6b7b\u4ea1\u3002<br \/>\nNMN\u901a\u8fc7\u6062\u590dNAD+\u7684\u6c34\u5e73\uff0c\u6539\u5584\u66b4\u9732\u65bc\u4e59\u4e8c\u9187\u4e01\u919a\u7684\u5375\u6bcd\u7ec6\u80de\u4e2d\u7ebf\u7c92\u4f53\u7684\u5206\u5e03\uff0c\u6765\u633d\u6551\u4e59\u4e8c\u9187\u4e01\u919a\u6240\u5f15\u8d77\u7684\u7f3a\u9677\uff0c\u4ece\u800c\u6d88\u9664\u4e86\u8fc7\u91cfROS\u7684\u6709\u5bb3\u5f71\u54cd\u3002<br \/>\n\u6587\u7ae0\u4f5c\u8005\u8868\u793a\uff0c\u8865\u5145NMN\u662f\u4fdd\u62a4\u5375\u6bcd\u7ec6\u80de\u514d\u53d7\u73af\u5883\u6c61\u67d3\u7269\u5f71\u54cd\u7684\u6709\u6548\u7b56\u7565\uff0c\u6709\u52a9\u65bc\u6539\u5584\u4eba\u7c7b\u548c\u52a8\u7269\u7684\u751f\u80b2\u80fd\u529b\uff0c\u89e3\u51b3\u65e5\u76ca\u4e25\u91cd\u7684\u4e0d\u80b2\u95ee\u9898\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-large wp-image-20184\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/05\/\u73af\u58832.jpg\" alt=\"\" width=\"900\" height=\"600\" srcset=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/05\/\u73af\u58832.jpg 960w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/05\/\u73af\u58832-300x200.jpg 300w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/05\/\u73af\u58832-768x512.jpg 768w\" sizes=\"auto, (max-width: 900px) 100vw, 900px\" \/><\/p>\n<p>&nbsp;<\/p>\n<div class=\"pvc_clear\"><\/div>\n<p id=\"pvc_stats_20182\" class=\"pvc_stats all  \" data-element-id=\"20182\" style=\"\"><i class=\"pvc-stats-icon medium\" aria-hidden=\"true\"><svg aria-hidden=\"true\" focusable=\"false\" data-prefix=\"far\" data-icon=\"chart-bar\" role=\"img\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\" class=\"svg-inline--fa fa-chart-bar fa-w-16 fa-2x\"><path fill=\"currentColor\" d=\"M396.8 352h22.4c6.4 0 12.8-6.4 12.8-12.8V108.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v230.4c0 6.4 6.4 12.8 12.8 12.8zm-192 0h22.4c6.4 0 12.8-6.4 12.8-12.8V140.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v198.4c0 6.4 6.4 12.8 12.8 12.8zm96 0h22.4c6.4 0 12.8-6.4 12.8-12.8V204.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v134.4c0 6.4 6.4 12.8 12.8 12.8zM496 400H48V80c0-8.84-7.16-16-16-16H16C7.16 64 0 71.16 0 80v336c0 17.67 14.33 32 32 32h464c8.84 0 16-7.16 16-16v-16c0-8.84-7.16-16-16-16zm-387.2-48h22.4c6.4 0 12.8-6.4 12.8-12.8v-70.4c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v70.4c0 6.4 6.4 12.8 12.8 12.8z\" class=\"\"><\/path><\/svg><\/i> <img loading=\"lazy\" decoding=\"async\" width=\"16\" height=\"16\" alt=\"Loading\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/plugins\/page-views-count\/ajax-loader-2x.gif\" border=0 \/><\/p>\n<div class=\"pvc_clear\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>NMN\u53ef\u4fdd\u62a4\u5375\u6bcd\u7ec6\u80de &#8211; \u6539\u5584\u751f\u80b2\u80fd\u529b \u8d8a\u6765\u8d8a\u4e25\u91cd\u7684\u73af\u5883\u6c61\u67d3\uff0c\u4e0d\u4ec5\u5f71\u54cd\u7740\u4eba\u4eec\u7684\u5c45\u4f4f\u73af\u5883\uff0c\u4e5f\u5728\u635f\u5bb3\u7740\u4eba\u4eec\u7684\u751f\u80b2\u80fd\u529b\u3002 \u800c\u8bb8\u591a\u5f71\u54cd\u751f\u6b96\u529f\u80fd\u7684\u7269\u8d28\uff0c\u5c31\u4e0d\u4ec5\u51fa\u73b0\u4e86\u5de5\u4e1a\u5236\u9020\u4e0a\uff0c\u4e5f\u9891\u7e41\u51fa\u73b0\u5728\u6211\u4eec\u5e38\u89c1\u7684\u5bb6\u5ead\u7269\u54c1\u4e2d\u3002 \u25b2 \u73af\u5883\u6c61\u67d3\u6240\u5bfc\u81f4\u7684\u751f\u80b2\u95ee\u9898\u5f15\u8d77\u4e86\u4eba\u4eec\u7684\u5173\u6ce8\u3002 \u4e59\u4e8c\u9187\u4e01\u919a\uff08EGBE\uff09\uff0c\u5c31\u662f\u4e00\u79cd\u751f\u6d3b\u4e2d\u5e38\u89c1\u7684\u300c\u751f\u6b96\u6bd2\u7d20\u300d\u3002\u5b83\u53ef\u71c3\uff0c\u6709\u6bd2\uff0c\u5177\u523a\u6fc0\u6027\u3002\u5370\u5237\u6cb9\u58a8\u4e36\u5370\u7ae0\u6cb9\u58a8\u4e36\u5899\u58c1\u6d82\u6599\u4e36\u55b7\u6f06\u7b49\uff0c\u4e3b\u8981\u6210\u5206\u90fd\u662f\u4e59\u4e8c\u9187\u4e01\u919a\u3002 \u5b83\u4f1a\u5f71\u54cd\u6210\u5e74\u7537\u6027\u4e36\u5973\u6027\u7684\u6027\u529f\u80fd\u548c\u751f\u80b2\u80fd\u529b\uff0c\u5e72\u6270\u6b63\u5e38\u751f\u6b96\uff0c\u5bf9\u5f8c\u4ee3\u4f1a\u9020\u6210\u5148\u5929\u7f3a\u9677\uff0c\u751a\u81f3\u662f\u80da\u80ce\u6b7b\u4ea1\u7b49\u4e0d\u5229\u5f71\u54cd\u3002 \u25b2 \u4e59\u4e8c\u9187\u4e01\u919a\u5e38\u7528\u65bc\u5de5\u4e1a\u548c\u5bb6\u5ead\u4ea7\u54c1\u7684\u5236\u9020\u3002 \u5357\u4eac\u519c\u4e1a\u5927\u5b66\u5728\u300aFrontiers in Cell and Developmental Biology\u300b\u4e0a\u53d1\u8868\u6587\u7ae0\uff0c\u53d1\u73b0\u4e59\u4e8c\u9187\u4e01\u919a\u66b4\u9732\uff0c\u5bfc\u81f4\u5375\u6bcd\u7ec6\u80de\u79ef\u805a\u6709\u5bb3\u7684\u542b\u6c27\u5206\u5b50\u6d3b\u6027\u6c27\uff08ROS\uff09\u548cDNA\u635f\u4f24\uff0c\u4ece\u800c\u5bfc\u81f4\u5375\u6bcd\u7ec6\u80de\u6b7b\u4ea1\u3002 NMN\u901a\u8fc7\u6062\u590dNAD+\u7684\u6c34\u5e73\uff0c\u6539\u5584\u66b4\u9732\u65bc\u4e59\u4e8c\u9187\u4e01\u919a\u7684\u5375\u6bcd\u7ec6\u80de\u4e2d\u7ebf\u7c92\u4f53\u7684\u5206\u5e03\uff0c\u6765\u633d\u6551\u4e59\u4e8c\u9187\u4e01\u919a\u6240\u5f15\u8d77\u7684\u7f3a\u9677\uff0c\u4ece\u800c\u6d88\u9664\u4e86\u8fc7\u91cfROS\u7684\u6709\u5bb3\u5f71\u54cd\u3002 \u6587\u7ae0\u4f5c\u8005\u8868\u793a\uff0c\u8865\u5145NMN\u662f\u4fdd\u62a4\u5375\u6bcd\u7ec6\u80de\u514d\u53d7\u73af\u5883\u6c61\u67d3\u7269\u5f71\u54cd\u7684\u6709\u6548\u7b56\u7565\uff0c\u6709\u52a9\u65bc\u6539\u5584\u4eba\u7c7b\u548c\u52a8\u7269\u7684\u751f\u80b2\u80fd\u529b\uff0c\u89e3\u51b3\u65e5\u76ca\u4e25\u91cd\u7684\u4e0d\u80b2\u95ee\u9898\u3002 &nbsp;<\/p>\n<div class=\"pvc_clear\"><\/div>\n<p id=\"pvc_stats_20182\" class=\"pvc_stats all  \" data-element-id=\"20182\" style=\"\"><i class=\"pvc-stats-icon medium\" aria-hidden=\"true\"><svg aria-hidden=\"true\" focusable=\"false\" data-prefix=\"far\" data-icon=\"chart-bar\" role=\"img\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\" class=\"svg-inline--fa fa-chart-bar fa-w-16 fa-2x\"><path fill=\"currentColor\" d=\"M396.8 352h22.4c6.4 0 12.8-6.4 12.8-12.8V108.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v230.4c0 6.4 6.4 12.8 12.8 12.8zm-192 0h22.4c6.4 0 12.8-6.4 12.8-12.8V140.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v198.4c0 6.4 6.4 12.8 12.8 12.8zm96 0h22.4c6.4 0 12.8-6.4 12.8-12.8V204.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v134.4c0 6.4 6.4 12.8 12.8 12.8zM496 400H48V80c0-8.84-7.16-16-16-16H16C7.16 64 0 71.16 0 80v336c0 17.67 14.33 32 32 32h464c8.84 0 16-7.16 16-16v-16c0-8.84-7.16-16-16-16zm-387.2-48h22.4c6.4 0 12.8-6.4 12.8-12.8v-70.4c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v70.4c0 6.4 6.4 12.8 12.8 12.8z\" class=\"\"><\/path><\/svg><\/i> <img loading=\"lazy\" decoding=\"async\" width=\"16\" height=\"16\" alt=\"Loading\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/plugins\/page-views-count\/ajax-loader-2x.gif\" border=0 \/><\/p>\n<div class=\"pvc_clear\"><\/div>\n","protected":false},"author":1,"featured_media":20185,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[172],"tags":[780],"class_list":["post-20182","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nmn-","tag-nmn"],"aioseo_notices":[],"_links":{"self":[{"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/posts\/20182","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=20182"}],"version-history":[{"count":1,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/posts\/20182\/revisions"}],"predecessor-version":[{"id":20186,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/posts\/20182\/revisions\/20186"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/media\/20185"}],"wp:attachment":[{"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=20182"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=20182"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=20182"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}