{"id":20129,"date":"2023-08-23T12:52:49","date_gmt":"2023-08-23T12:52:49","guid":{"rendered":"http:\/\/johnhealth.blog\/ch\/?p=20129"},"modified":"2023-08-23T12:57:42","modified_gmt":"2023-08-23T12:57:42","slug":"%e3%80%8a%e6%b7%b1%e8%b0%88nmn%e7%b3%bb%e5%88%97-%e4%b8%a5%e9%87%8d%e7%89%b9%e6%ae%8a%e4%bc%a0%e6%9f%93%e6%80%a7%e8%82%ba%e7%82%8e11%e3%80%8b-%e8%be%9b%e5%85%8b%e8%8e%b1%e5%b0%94%e5%8a%9b%e6%8c%ba","status":"publish","type":"post","link":"http:\/\/johnhealth.blog\/ch\/?p=20129","title":{"rendered":"\u300a\u6df1\u8c08NMN\u7cfb\u5217-\u4e25\u91cd\u7279\u6b8a\u4f20\u67d3\u6027\u80ba\u708e11\u300b \u8f9b\u514b\u83b1\u5c14\u529b\u633a\u201c\u63d0\u9ad8NAD+\u6c34\u5e73\u80fd\u9632\u6cbb\u65b0\u51a0\u201d"},"content":{"rendered":"<p>\u540c\u6837\u57282022\u5e744\u6708\uff0cNMN\u9886\u57df\u7740\u540d\u5b66\u8005\u5927\u536b\u00b7\u8f9b\u514b\u83b1\u5c14\u5728\u300aCell\u300b\u5b50\u520a\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u7efc\u8ff0\u6587\u7ae0\uff0c\u63a2\u8ba8\u4e86NAD+\u4e0e\u65b0\u51a0\u75c5\u6bd2\u7684\u5173\u7cfb\u3002\u6587\u7ae0\u6307\u51fa\uff0c\u60a3\u6709\u7cd6\u5c3f\u75c5\u4e36\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u8001\u5e74\u60a3\u8005\u5176\u7ec4\u7ec7\u5668\u5b98\u7684NAD+\u6d53\u5ea6\u8f83\u4f4e\uff0c\u8fd9\u53ef\u80fd\u662f\u8fd9\u7c7b\u4eba\u7fa4\u66f4\u5bb9\u6613\u5f97\u65b0\u51a0\u91cd\u75c7\u7684\u539f\u56e0\u3002<\/p>\n<p>\u8f9b\u514b\u83b1\u5c14\u8fd8\u8868\u793a\uff0c\u65b0\u51a0\u611f\u67d3\u4f1a\u8fdb\u4e00\u6b65\u6d88\u8017\u4f53\u5185NAD+\u50a8\u5907\uff0c\u56e0\u6b64\u53ef\u5c06NAD+\u524d\u4f53\u5982NMN\u4f5c\u4e3a\u75c5\u6bd2\u611f\u67d3\u671f\u95f4\u6297\u611f\u67d3\u4e36\u6297\u708e\u7684\u65b0\u5174\u514d\u75ab\u8c03\u8282\u5242\uff0c\u5b83\u662f\u4eba\u7c7b\u5bf9\u6297\u65b0\u51a0\u7b49\u75c5\u6bd2\u611f\u67d3\u7684\u91cd\u8981\u6b66\u5668\u3002<br \/>\n\u8fd9\u7bc7\u7efc\u8ff0\u5c31\u662f\u5c06\u4e4b\u524d\u7684\u76f8\u5173\u7814\u7a76\u8fdb\u884c\u4e86\u603b\u7ed3\uff0c\u5f3a\u8c03\u4e86NAD+\u5728\u65b0\u51a0\u611f\u67d3\u4e2d\u7684\u91cd\u8981\u6027\uff0c\u662f\u4e00\u4e2a\u5f88\u6709\u6f5c\u529b\u7684\u6cbb\u7597\u9776\u70b9\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-20130\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/05\/\u6df1\u8c08NMN\u7cfb\u5217-\u80ba\u708e11.jpg\" alt=\"\" width=\"940\" height=\"788\" srcset=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/05\/\u6df1\u8c08NMN\u7cfb\u5217-\u80ba\u708e11.jpg 940w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/05\/\u6df1\u8c08NMN\u7cfb\u5217-\u80ba\u708e11-300x251.jpg 300w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/05\/\u6df1\u8c08NMN\u7cfb\u5217-\u80ba\u708e11-768x644.jpg 768w\" sizes=\"auto, (max-width: 940px) 100vw, 940px\" \/><\/p>\n<p>\u5168\u6587\u8fde\u7ed3\uff1a<a href=\"http:\/\/johnhealth.blog\/ch\/?p=396\">NMN\u53ef\u4ee5\u5e2e\u52a9\u5bf9\u6297COVID-19\u5417 \u2013 John\u54e5\u8c08\u5065\u5eb7 (johnhealth.blog)<\/a><\/p>\n<p>Minyan Zheng, Michael B. Schultz, David A. Sinclair,<br \/>\nNAD+ in COVID-19 and viral infections, Trends in Immunology, Volume 43, Issue 4, 2022, Pages 283-295, ISSN 1471-4906, https:\/\/doi.org\/10.1016\/j.it.2022.02.001.<\/p>\n<div class=\"pvc_clear\"><\/div>\n<p id=\"pvc_stats_20129\" class=\"pvc_stats all  \" data-element-id=\"20129\" style=\"\"><i class=\"pvc-stats-icon medium\" aria-hidden=\"true\"><svg aria-hidden=\"true\" focusable=\"false\" data-prefix=\"far\" data-icon=\"chart-bar\" role=\"img\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\" class=\"svg-inline--fa fa-chart-bar fa-w-16 fa-2x\"><path fill=\"currentColor\" d=\"M396.8 352h22.4c6.4 0 12.8-6.4 12.8-12.8V108.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v230.4c0 6.4 6.4 12.8 12.8 12.8zm-192 0h22.4c6.4 0 12.8-6.4 12.8-12.8V140.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v198.4c0 6.4 6.4 12.8 12.8 12.8zm96 0h22.4c6.4 0 12.8-6.4 12.8-12.8V204.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v134.4c0 6.4 6.4 12.8 12.8 12.8zM496 400H48V80c0-8.84-7.16-16-16-16H16C7.16 64 0 71.16 0 80v336c0 17.67 14.33 32 32 32h464c8.84 0 16-7.16 16-16v-16c0-8.84-7.16-16-16-16zm-387.2-48h22.4c6.4 0 12.8-6.4 12.8-12.8v-70.4c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v70.4c0 6.4 6.4 12.8 12.8 12.8z\" class=\"\"><\/path><\/svg><\/i> <img loading=\"lazy\" decoding=\"async\" width=\"16\" height=\"16\" alt=\"Loading\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/plugins\/page-views-count\/ajax-loader-2x.gif\" border=0 \/><\/p>\n<div class=\"pvc_clear\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u540c\u6837\u57282022\u5e744\u6708\uff0cNMN\u9886\u57df\u7740\u540d\u5b66\u8005\u5927\u536b\u00b7\u8f9b\u514b\u83b1\u5c14\u5728\u300aCell\u300b\u5b50\u520a\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u7efc\u8ff0\u6587\u7ae0\uff0c\u63a2\u8ba8\u4e86NAD+\u4e0e\u65b0\u51a0\u75c5\u6bd2\u7684\u5173\u7cfb\u3002\u6587\u7ae0\u6307\u51fa\uff0c\u60a3\u6709\u7cd6\u5c3f\u75c5\u4e36\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u8001\u5e74\u60a3\u8005\u5176\u7ec4\u7ec7\u5668\u5b98\u7684NAD+\u6d53\u5ea6\u8f83\u4f4e\uff0c\u8fd9\u53ef\u80fd\u662f\u8fd9\u7c7b\u4eba\u7fa4\u66f4\u5bb9\u6613\u5f97\u65b0\u51a0\u91cd\u75c7\u7684\u539f\u56e0\u3002 \u8f9b\u514b\u83b1\u5c14\u8fd8\u8868\u793a\uff0c\u65b0\u51a0\u611f\u67d3\u4f1a\u8fdb\u4e00\u6b65\u6d88\u8017\u4f53\u5185NAD+\u50a8\u5907\uff0c\u56e0\u6b64\u53ef\u5c06NAD+\u524d\u4f53\u5982NMN\u4f5c\u4e3a\u75c5\u6bd2\u611f\u67d3\u671f\u95f4\u6297\u611f\u67d3\u4e36\u6297\u708e\u7684\u65b0\u5174\u514d\u75ab\u8c03\u8282\u5242\uff0c\u5b83\u662f\u4eba\u7c7b\u5bf9\u6297\u65b0\u51a0\u7b49\u75c5\u6bd2\u611f\u67d3\u7684\u91cd\u8981\u6b66\u5668\u3002 \u8fd9\u7bc7\u7efc\u8ff0\u5c31\u662f\u5c06\u4e4b\u524d\u7684\u76f8\u5173\u7814\u7a76\u8fdb\u884c\u4e86\u603b\u7ed3\uff0c\u5f3a\u8c03\u4e86NAD+\u5728\u65b0\u51a0\u611f\u67d3\u4e2d\u7684\u91cd\u8981\u6027\uff0c\u662f\u4e00\u4e2a\u5f88\u6709\u6f5c\u529b\u7684\u6cbb\u7597\u9776\u70b9\u3002 \u5168\u6587\u8fde\u7ed3\uff1aNMN\u53ef\u4ee5\u5e2e\u52a9\u5bf9\u6297COVID-19\u5417 \u2013 John\u54e5\u8c08\u5065\u5eb7 (johnhealth.blog) Minyan Zheng, Michael B. Schultz, David A. Sinclair, NAD+ in COVID-19 and viral infections, Trends in Immunology, Volume 43, Issue 4, 2022, Pages 283-295, ISSN 1471-4906, https:\/\/doi.org\/10.1016\/j.it.2022.02.001.<\/p>\n<div class=\"pvc_clear\"><\/div>\n<p id=\"pvc_stats_20129\" class=\"pvc_stats all  \" data-element-id=\"20129\" style=\"\"><i class=\"pvc-stats-icon medium\" aria-hidden=\"true\"><svg aria-hidden=\"true\" focusable=\"false\" data-prefix=\"far\" data-icon=\"chart-bar\" role=\"img\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\" class=\"svg-inline--fa fa-chart-bar fa-w-16 fa-2x\"><path fill=\"currentColor\" d=\"M396.8 352h22.4c6.4 0 12.8-6.4 12.8-12.8V108.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v230.4c0 6.4 6.4 12.8 12.8 12.8zm-192 0h22.4c6.4 0 12.8-6.4 12.8-12.8V140.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v198.4c0 6.4 6.4 12.8 12.8 12.8zm96 0h22.4c6.4 0 12.8-6.4 12.8-12.8V204.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v134.4c0 6.4 6.4 12.8 12.8 12.8zM496 400H48V80c0-8.84-7.16-16-16-16H16C7.16 64 0 71.16 0 80v336c0 17.67 14.33 32 32 32h464c8.84 0 16-7.16 16-16v-16c0-8.84-7.16-16-16-16zm-387.2-48h22.4c6.4 0 12.8-6.4 12.8-12.8v-70.4c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v70.4c0 6.4 6.4 12.8 12.8 12.8z\" class=\"\"><\/path><\/svg><\/i> <img loading=\"lazy\" decoding=\"async\" width=\"16\" height=\"16\" alt=\"Loading\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/plugins\/page-views-count\/ajax-loader-2x.gif\" border=0 \/><\/p>\n<div class=\"pvc_clear\"><\/div>\n","protected":false},"author":1,"featured_media":20130,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[191,172,734],"tags":[295,659,728],"class_list":["post-20129","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid-19","category-nmn-","category-nmn","tag-covid-19","tag-659","tag-nmn"],"aioseo_notices":[],"_links":{"self":[{"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/posts\/20129","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=20129"}],"version-history":[{"count":1,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/posts\/20129\/revisions"}],"predecessor-version":[{"id":20131,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/posts\/20129\/revisions\/20131"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/media\/20130"}],"wp:attachment":[{"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=20129"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=20129"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=20129"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}