{"id":19970,"date":"2023-04-28T01:16:16","date_gmt":"2023-04-28T01:16:16","guid":{"rendered":"http:\/\/johnhealth.blog\/ch\/?p=19970"},"modified":"2023-04-28T01:16:16","modified_gmt":"2023-04-28T01:16:16","slug":"%e3%80%8a%e6%b7%b1%e8%b0%88nmn%e7%b3%bb%e5%88%97-%e4%b8%a5%e9%87%8d%e7%89%b9%e6%ae%8a%e4%bc%a0%e6%9f%93%e6%80%a7%e8%82%ba%e7%82%8e5%e3%80%8b-nmn%e6%88%96%e8%ae%b8%e8%83%bd%e6%94%b9%e5%96%84%e6%96%b0","status":"publish","type":"post","link":"http:\/\/johnhealth.blog\/ch\/?p=19970","title":{"rendered":"\u300a\u6df1\u8c08NMN\u7cfb\u5217-\u4e25\u91cd\u7279\u6b8a\u4f20\u67d3\u6027\u80ba\u708e5\u300b NMN\u6216\u8bb8\u80fd\u6539\u5584\u65b0\u51a0\u5e76\u53d1\u7684\u80be\u635f\u4f24"},"content":{"rendered":"<p>\u524d\u56db\u7bc7\u7814\u7a76\u8bba\u6587\u5927\u591a\u53d1\u8868\u65bc2020\u5e74\uff0c\u5f53\u65f6\u65b0\u51a0\u75c5\u6bd2\u521a\u5f00\u59cb\u6d41\u884c\u3002\u7814\u7a76\u4eba\u5458\u901a\u8fc7\u7814\u7a76NAD+\u5728\u65b0\u51a0\u611f\u67d3\u4e2d\u7684\u4f5c\u7528\uff0c\u53d1\u73b0\u5b83\u53ef\u4ee5\u6291\u5236\u7ec6\u80de\u56e0\u5b50\u98ce\u66b4\u4e36\u652f\u6301\u514d\u75ab\u7cfb\u7edf\uff0c\u5e76\u51cf\u5c11\u7ec6\u80de\u6b7b\u4ea1\u3002\u56e0\u6b64\uff0c\u4ed6\u4eec\u731c\u60f3NAD+\u53ca\u5176\u524d\u4f53\u53ef\u80fd\u6709\u52a9\u65bc\u9884\u9632\u65b0\u51a0\u75c5\u6bd2\u611f\u67d3\uff0c\u4f46\u8fd9\u4e00\u731c\u60f3\u5c1a\u672a\u7ecf\u8fc7\u9a8c\u8bc1\u3002<\/p>\n<p>\u5728\u65b0\u51a0\u80ba\u708e\u91cd\u75c7\u75c5\u4eba\u4e2d\uff0c\u6025\u6027\u80be\u635f\u4f24\u662f\u4e00\u4e2a\u5e38\u89c1\u7684\u5e76\u53d1\u75c7\u3002\u6700\u8fd1\uff0c\u54c8\u4f5b\u5927\u5b66\u533b\u5b66\u9662\u7684\u7814\u7a76\u56e2\u961f\u5728\u80be\u810f\u75c5\u5b66\u9886\u57df\u7684\u9876\u5c16\u671f\u520a\u300aKidney International Reports\u300b\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u7814\u7a76\u8bba\u6587\u3002<\/p>\n<p>\u7814\u7a76\u4eba\u5458\u8fdb\u884c\u4e86\u65b0\u51a0\u75c5\u60a3\u8005\u5c3f\u6db2\u4ee3\u8c22\u7ec4\u5b66\u7684\u5206\u6790\uff0c\u53d1\u73b0\u60a3\u6709\u6025\u6027\u80be\u635f\u4f24\u7684\u65b0\u51a0\u60a3\u8005\uff0c\u5176\u5c3f\u6db2\u4e2dNAD+\u76f8\u5173\u4ee3\u8c22\u7269\uff08\u5305\u62ecNMN\uff09\u660e\u663e\u4f4e\u65bc\u672a\u53d1\u751f\u6025\u6027\u80be\u635f\u4f24\u7684\u65b0\u51a0\u60a3\u8005\u3002<\/p>\n<p>\u7814\u7a76\u4eba\u5458\u8ba4\u4e3a\u901a\u8fc7\u8865\u5145NAD+\u524d\u4f53\uff0c\u5982NMN\uff0c\u53ef\u80fd\u6709\u52a9\u65bc\u6cbb\u7597\u65b0\u51a0\u80ba\u708e\u60a3\u8005\u5e76\u53d1\u7684\u80be\u635f\u4f24\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19971\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/04\/\u6df1\u8c08NMN\u7cfb\u5217-\u80ba\u708e5.jpg\" alt=\"\" width=\"940\" height=\"788\" srcset=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/04\/\u6df1\u8c08NMN\u7cfb\u5217-\u80ba\u708e5.jpg 940w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/04\/\u6df1\u8c08NMN\u7cfb\u5217-\u80ba\u708e5-300x251.jpg 300w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/04\/\u6df1\u8c08NMN\u7cfb\u5217-\u80ba\u708e5-768x644.jpg 768w\" sizes=\"auto, (max-width: 940px) 100vw, 940px\" \/><\/p>\n<p>\u5168\u6587\u8fde\u7ed3\uff1a<a href=\"http:\/\/johnhealth.blog\/ch\/?p=19503\">\u65b0\u51a0\u75c5\u6bd2\u4e0eNMN \uff08\u4ece\u9884\u9632\u5230\u6cbb\u6108\uff09\u5927\u6c47\u603b \u2013 John\u54e5\u8c08\u5065\u5eb7 (johnhealth.blog)<\/a><\/p>\n<p>Nicotinamide Adenine Dinucleotide Biosynthetic Impairment and Urinary Metabolomic Alterations Observed in Hospitalized Adults With COVID-19\uff0dRelated Acute Kidney Injury. Raines, Nathan H. et al. Kidney International Reports, Volume 6, Issue 12, 3002 &#8211; 3013<\/p>\n<div class=\"pvc_clear\"><\/div>\n<p id=\"pvc_stats_19970\" class=\"pvc_stats all  \" data-element-id=\"19970\" style=\"\"><i class=\"pvc-stats-icon medium\" aria-hidden=\"true\"><svg aria-hidden=\"true\" focusable=\"false\" data-prefix=\"far\" data-icon=\"chart-bar\" role=\"img\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\" class=\"svg-inline--fa fa-chart-bar fa-w-16 fa-2x\"><path fill=\"currentColor\" d=\"M396.8 352h22.4c6.4 0 12.8-6.4 12.8-12.8V108.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v230.4c0 6.4 6.4 12.8 12.8 12.8zm-192 0h22.4c6.4 0 12.8-6.4 12.8-12.8V140.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v198.4c0 6.4 6.4 12.8 12.8 12.8zm96 0h22.4c6.4 0 12.8-6.4 12.8-12.8V204.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v134.4c0 6.4 6.4 12.8 12.8 12.8zM496 400H48V80c0-8.84-7.16-16-16-16H16C7.16 64 0 71.16 0 80v336c0 17.67 14.33 32 32 32h464c8.84 0 16-7.16 16-16v-16c0-8.84-7.16-16-16-16zm-387.2-48h22.4c6.4 0 12.8-6.4 12.8-12.8v-70.4c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v70.4c0 6.4 6.4 12.8 12.8 12.8z\" class=\"\"><\/path><\/svg><\/i> <img loading=\"lazy\" decoding=\"async\" width=\"16\" height=\"16\" alt=\"Loading\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/plugins\/page-views-count\/ajax-loader-2x.gif\" border=0 \/><\/p>\n<div class=\"pvc_clear\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u524d\u56db\u7bc7\u7814\u7a76\u8bba\u6587\u5927\u591a\u53d1\u8868\u65bc2020\u5e74\uff0c\u5f53\u65f6\u65b0\u51a0\u75c5\u6bd2\u521a\u5f00\u59cb\u6d41\u884c\u3002\u7814\u7a76\u4eba\u5458\u901a\u8fc7\u7814\u7a76NAD+\u5728\u65b0\u51a0\u611f\u67d3\u4e2d\u7684\u4f5c\u7528\uff0c\u53d1\u73b0\u5b83\u53ef\u4ee5\u6291\u5236\u7ec6\u80de\u56e0\u5b50\u98ce\u66b4\u4e36\u652f\u6301\u514d\u75ab\u7cfb\u7edf\uff0c\u5e76\u51cf\u5c11\u7ec6\u80de\u6b7b\u4ea1\u3002\u56e0\u6b64\uff0c\u4ed6\u4eec\u731c\u60f3NAD+\u53ca\u5176\u524d\u4f53\u53ef\u80fd\u6709\u52a9\u65bc\u9884\u9632\u65b0\u51a0\u75c5\u6bd2\u611f\u67d3\uff0c\u4f46\u8fd9\u4e00\u731c\u60f3\u5c1a\u672a\u7ecf\u8fc7\u9a8c\u8bc1\u3002 \u5728\u65b0\u51a0\u80ba\u708e\u91cd\u75c7\u75c5\u4eba\u4e2d\uff0c\u6025\u6027\u80be\u635f\u4f24\u662f\u4e00\u4e2a\u5e38\u89c1\u7684\u5e76\u53d1\u75c7\u3002\u6700\u8fd1\uff0c\u54c8\u4f5b\u5927\u5b66\u533b\u5b66\u9662\u7684\u7814\u7a76\u56e2\u961f\u5728\u80be\u810f\u75c5\u5b66\u9886\u57df\u7684\u9876\u5c16\u671f\u520a\u300aKidney International Reports\u300b\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u7814\u7a76\u8bba\u6587\u3002 \u7814\u7a76\u4eba\u5458\u8fdb\u884c\u4e86\u65b0\u51a0\u75c5\u60a3\u8005\u5c3f\u6db2\u4ee3\u8c22\u7ec4\u5b66\u7684\u5206\u6790\uff0c\u53d1\u73b0\u60a3\u6709\u6025\u6027\u80be\u635f\u4f24\u7684\u65b0\u51a0\u60a3\u8005\uff0c\u5176\u5c3f\u6db2\u4e2dNAD+\u76f8\u5173\u4ee3\u8c22\u7269\uff08\u5305\u62ecNMN\uff09\u660e\u663e\u4f4e\u65bc\u672a\u53d1\u751f\u6025\u6027\u80be\u635f\u4f24\u7684\u65b0\u51a0\u60a3\u8005\u3002 \u7814\u7a76\u4eba\u5458\u8ba4\u4e3a\u901a\u8fc7\u8865\u5145NAD+\u524d\u4f53\uff0c\u5982NMN\uff0c\u53ef\u80fd\u6709\u52a9\u65bc\u6cbb\u7597\u65b0\u51a0\u80ba\u708e\u60a3\u8005\u5e76\u53d1\u7684\u80be\u635f\u4f24\u3002 \u5168\u6587\u8fde\u7ed3\uff1a\u65b0\u51a0\u75c5\u6bd2\u4e0eNMN \uff08\u4ece\u9884\u9632\u5230\u6cbb\u6108\uff09\u5927\u6c47\u603b \u2013 John\u54e5\u8c08\u5065\u5eb7 (johnhealth.blog) Nicotinamide Adenine Dinucleotide Biosynthetic Impairment and Urinary Metabolomic Alterations Observed in Hospitalized Adults With COVID-19\uff0dRelated Acute Kidney Injury. Raines, Nathan H. et al. 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