{"id":19660,"date":"2023-02-06T22:11:21","date_gmt":"2023-02-06T22:11:21","guid":{"rendered":"http:\/\/johnhealth.blog\/ch\/?p=19660"},"modified":"2023-02-06T22:11:21","modified_gmt":"2023-02-06T22:11:21","slug":"%e6%b7%b1%e8%b0%88nmn%e7%b3%bb%e5%88%97-%e8%82%8c%e5%b0%91%e7%97%87-2","status":"publish","type":"post","link":"http:\/\/johnhealth.blog\/ch\/?p=19660","title":{"rendered":"\u6df1\u8c08NMN\u7cfb\u5217-\u808c\u5c11\u75c7-2"},"content":{"rendered":"<p>\u300c\u808c\u5c11\u75c7\u300d\u662f\u8001\u5e74\u5931\u80fd\u7684\u51f6\u624b\uff0c\u7279\u5fb5\u662f\u6301\u7eed\u4e14\u5168\u8eab\u666e\u904d\u7684\u9aa8\u9abc\u808c\u91cd\u91cf\u53ca\u529f\u80fd\u51cf\u5c11\uff0c\u4f34\u968f\u53ef\u80fd\u9020\u6210\u5931\u80fd\u4e36\u751f\u6d3b\u54c1\u8d28\u4e0b\u964d\uff0c\u751a\u81f3\u662f\u751f\u6d3b\u65e0\u6cd5\u81ea\u7406\u4ee5\u53ca\u6b7b\u4ea1\u98ce\u9669\u589e\u52a0&#8230;<\/p>\n<p>\u745e\u58eb\u6d1b\u6851\u8054\u90a6\u7406\u5de5\u5b66\u9662\u7684\u79d1\u7814\u56e2\u961f\u53d1\u73b0\uff0c\u63d0\u5347NAD+\u53ef\u4ee5\u589e\u52a0\u808c\u8089\u5e72\u7ec6\u80de (MuSC) \u7684\u6570\u91cf\u548c\u8d28\u91cf\uff0c\u5e76\u589e\u5f3a\u4e86\u8001\u5e74\u5c0f\u9f20\u7684\u808c\u8089\u518d\u751f\uff0c\u90e8\u5206\u539f\u56e0\u662f\u901a\u8fc7\u6539\u5584\u7c92\u7ebf\u4f53\u529f\u80fd\u548c\u9632\u6b62 \u808c\u8089\u5e72\u7ec6\u80de (MuSC)\u8870\u8001\u3002<br \/>\n\u6b64\u79d1\u7814\u6210\u679c\u53d1\u8868\u5728\u4e09\u5927\u9876\u7ea7\u671f\u520a\u4e4b\u4e00 Science<\/p>\n<p>Zhang H, Ryu D, Wu Y, Gariani K, Wang X, Luan P, D&#8217;Amico D, Ropelle ER, Lutolf MP, Aebersold R, Schoonjans K, Menzies KJ, Auwerx J. NAD\u207a repletion improves mitochondrial and stem cell function and enhances life span in mice. Science. 2016 Jun 17;352(6292):1436-43. doi: 10.1126\/science.aaf2693. Epub 2016 Apr 28. PMID: 27127236.<\/p>\n<p><a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.aaf2693\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-19661\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/02\/science-2016.jpg\" alt=\"\" width=\"526\" height=\"527\" srcset=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/02\/science-2016.jpg 526w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/02\/science-2016-300x300.jpg 300w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2023\/02\/science-2016-150x150.jpg 150w\" sizes=\"auto, (max-width: 526px) 100vw, 526px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<div class=\"pvc_clear\"><\/div>\n<p id=\"pvc_stats_19660\" class=\"pvc_stats all  \" data-element-id=\"19660\" style=\"\"><i class=\"pvc-stats-icon medium\" aria-hidden=\"true\"><svg aria-hidden=\"true\" focusable=\"false\" data-prefix=\"far\" data-icon=\"chart-bar\" role=\"img\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\" class=\"svg-inline--fa fa-chart-bar fa-w-16 fa-2x\"><path fill=\"currentColor\" d=\"M396.8 352h22.4c6.4 0 12.8-6.4 12.8-12.8V108.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v230.4c0 6.4 6.4 12.8 12.8 12.8zm-192 0h22.4c6.4 0 12.8-6.4 12.8-12.8V140.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v198.4c0 6.4 6.4 12.8 12.8 12.8zm96 0h22.4c6.4 0 12.8-6.4 12.8-12.8V204.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v134.4c0 6.4 6.4 12.8 12.8 12.8zM496 400H48V80c0-8.84-7.16-16-16-16H16C7.16 64 0 71.16 0 80v336c0 17.67 14.33 32 32 32h464c8.84 0 16-7.16 16-16v-16c0-8.84-7.16-16-16-16zm-387.2-48h22.4c6.4 0 12.8-6.4 12.8-12.8v-70.4c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v70.4c0 6.4 6.4 12.8 12.8 12.8z\" class=\"\"><\/path><\/svg><\/i> <img loading=\"lazy\" decoding=\"async\" width=\"16\" height=\"16\" alt=\"Loading\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/plugins\/page-views-count\/ajax-loader-2x.gif\" border=0 \/><\/p>\n<div class=\"pvc_clear\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u300c\u808c\u5c11\u75c7\u300d\u662f\u8001\u5e74\u5931\u80fd\u7684\u51f6\u624b\uff0c\u7279\u5fb5\u662f\u6301\u7eed\u4e14\u5168\u8eab\u666e\u904d\u7684\u9aa8\u9abc\u808c\u91cd\u91cf\u53ca\u529f\u80fd\u51cf\u5c11\uff0c\u4f34\u968f\u53ef\u80fd\u9020\u6210\u5931\u80fd\u4e36\u751f\u6d3b\u54c1\u8d28\u4e0b\u964d\uff0c\u751a\u81f3\u662f\u751f\u6d3b\u65e0\u6cd5\u81ea\u7406\u4ee5\u53ca\u6b7b\u4ea1\u98ce\u9669\u589e\u52a0&#8230; \u745e\u58eb\u6d1b\u6851\u8054\u90a6\u7406\u5de5\u5b66\u9662\u7684\u79d1\u7814\u56e2\u961f\u53d1\u73b0\uff0c\u63d0\u5347NAD+\u53ef\u4ee5\u589e\u52a0\u808c\u8089\u5e72\u7ec6\u80de (MuSC) \u7684\u6570\u91cf\u548c\u8d28\u91cf\uff0c\u5e76\u589e\u5f3a\u4e86\u8001\u5e74\u5c0f\u9f20\u7684\u808c\u8089\u518d\u751f\uff0c\u90e8\u5206\u539f\u56e0\u662f\u901a\u8fc7\u6539\u5584\u7c92\u7ebf\u4f53\u529f\u80fd\u548c\u9632\u6b62 \u808c\u8089\u5e72\u7ec6\u80de (MuSC)\u8870\u8001\u3002 \u6b64\u79d1\u7814\u6210\u679c\u53d1\u8868\u5728\u4e09\u5927\u9876\u7ea7\u671f\u520a\u4e4b\u4e00 Science Zhang H, Ryu D, Wu Y, Gariani K, Wang X, Luan P, D&#8217;Amico D, Ropelle ER, Lutolf MP, Aebersold R, Schoonjans K, Menzies KJ, Auwerx J. NAD\u207a repletion improves mitochondrial and stem cell function and enhances life span in mice. Science. 2016 Jun 17;352(6292):1436-43. doi: 10.1126\/science.aaf2693. Epub 2016 Apr 28. PMID: 27127236. [&hellip;]<\/p>\n<div class=\"pvc_clear\"><\/div>\n<p id=\"pvc_stats_19660\" class=\"pvc_stats all  \" data-element-id=\"19660\" style=\"\"><i class=\"pvc-stats-icon medium\" aria-hidden=\"true\"><svg aria-hidden=\"true\" focusable=\"false\" data-prefix=\"far\" data-icon=\"chart-bar\" role=\"img\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\" class=\"svg-inline--fa fa-chart-bar fa-w-16 fa-2x\"><path fill=\"currentColor\" d=\"M396.8 352h22.4c6.4 0 12.8-6.4 12.8-12.8V108.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v230.4c0 6.4 6.4 12.8 12.8 12.8zm-192 0h22.4c6.4 0 12.8-6.4 12.8-12.8V140.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v198.4c0 6.4 6.4 12.8 12.8 12.8zm96 0h22.4c6.4 0 12.8-6.4 12.8-12.8V204.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v134.4c0 6.4 6.4 12.8 12.8 12.8zM496 400H48V80c0-8.84-7.16-16-16-16H16C7.16 64 0 71.16 0 80v336c0 17.67 14.33 32 32 32h464c8.84 0 16-7.16 16-16v-16c0-8.84-7.16-16-16-16zm-387.2-48h22.4c6.4 0 12.8-6.4 12.8-12.8v-70.4c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v70.4c0 6.4 6.4 12.8 12.8 12.8z\" class=\"\"><\/path><\/svg><\/i> <img loading=\"lazy\" decoding=\"async\" width=\"16\" height=\"16\" alt=\"Loading\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/plugins\/page-views-count\/ajax-loader-2x.gif\" border=0 \/><\/p>\n<div class=\"pvc_clear\"><\/div>\n","protected":false},"author":1,"featured_media":19661,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[172,342],"tags":[684,685,687,686],"class_list":{"0":"post-19660","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","6":"hentry","7":"category-nmn-","8":"category-342","9":"tag-nmn","11":"tag-687","12":"tag-686"},"aioseo_notices":[],"_links":{"self":[{"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/posts\/19660","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=19660"}],"version-history":[{"count":1,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/posts\/19660\/revisions"}],"predecessor-version":[{"id":19662,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/posts\/19660\/revisions\/19662"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=\/wp\/v2\/media\/19661"}],"wp:attachment":[{"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=19660"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=19660"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/johnhealth.blog\/ch\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=19660"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}