{"id":19656,"date":"2023-02-06T22:03:30","date_gmt":"2023-02-06T22:03:30","guid":{"rendered":"http:\/\/johnhealth.blog\/ch\/?p=19656"},"modified":"2023-02-07T04:11:39","modified_gmt":"2023-02-07T04:11:39","slug":"%e6%b7%b1%e8%b0%88nmn%e7%b3%bb%e5%88%97-%e8%82%8c%e5%b0%91%e7%97%87-1","status":"publish","type":"post","link":"http:\/\/johnhealth.blog\/ch\/?p=19656","title":{"rendered":"\u6df1\u8c08NMN\u7cfb\u5217-\u808c\u5c11\u75c7-1"},"content":{"rendered":"

\u5728\u7f8e\u56fd\u7684\u4e00\u9879\u7814\u7a76\u4e2d\u53d1\u73b0\uff0c80\u5c81\u4ee5\u4e0a\u7684\u65cf\u7fa4\u4e2d\uff0c43%\u81f360%\u7684\u7537\u6027\u548c 53%\u81f357%\u7684\u5973\u6027\u60a3\u6709\u808c\u5c11\u75c7\uff0c\u7531\u65bc\u808c\u5c11\u75c7\u4f1a\u5bfc\u81f4\u808c\u8089\u529b\u91cf\u51cf\u5c11\uff0c\u4e0b\u80a2\u529f\u80fd\u53d8\u5dee\uff0c\u56e0\u6b64\u8f83\u6613\u8dcc\u5012\u4e36\u589e\u52a0\u5931\u80fd\u98ce\u9669\uff0c\u5927\u5e45\u63d0\u5347\u8001\u5e74\u5f8c\u5931\u80fd\u7684\u6bd4\u7387…<\/p>\n

\u7f8e\u56fd\u54c8\u4f5b\u5927\u5b66\u8870\u8001\u751f\u7269\u5b66\u4e2d\u5fc3\u7684\u79d1\u7814\u56e2\u961f\u53d1\u73b0\uff0cNMN\u4ecb\u5165\u7684\u8001\u5e74\u5c0f\u9f20\u53ef\u663e\u7740\u6539\u5584\u808c\u8089\u529f\u80fd\u3002\u4f8b\u5982\uff0c\u7528 NMN\uff08500 mg\/\u5929 \uff0c\u8fde\u7eed 7 \u5929\uff09\u4ecb\u5165\u7684\u8001\u5e74\u5c0f\u9f20\uff0c\u901a\u8fc7\u589e\u52a0\u7c92\u7ebf\u4f53\u529f\u80fd\u4e36\u589e\u52a0 ATP \u4ea7\u751f\u4e36\u51cf\u5c11\u708e\u75c7\u548c\u5c06\u7cd6\u9175\u89e3 II \u578b\u808c\u7ea4\u7ef4\u8f6c\u6362\u4e3a\u66f4\u591a\u6c27\u5316\u7ea4\u7ef4\u7c7b\u578b\u3002<\/p>\n

\u6b64\u79d1\u7814\u6210\u679c\u53d1\u8868\u5728\u4e09\u5927\u9876\u7ea7\u671f\u520a\u4e4b\u4e00 Cell
\nGomes AP, Price NL, Ling AJ, Moslehi JJ, Montgomery MK, Rajman L, White JP, Teodoro JS, Wrann CD, Hubbard BP, Mercken EM, Palmeira CM, de Cabo R, Rolo AP, Turner N, Bell EL, Sinclair DA. Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell. 2013 Dec 19;155(7):1624-38. doi: 10.1016\/j.cell.2013.11.037. PMID: 24360282; PMCID: PMC4076149.<\/p>\n

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\u5728\u7f8e\u56fd\u7684\u4e00\u9879\u7814\u7a76\u4e2d\u53d1\u73b0\uff0c80\u5c81\u4ee5\u4e0a\u7684\u65cf\u7fa4\u4e2d\uff0c43%\u81f360%\u7684\u7537\u6027\u548c 53%\u81f357%\u7684\u5973\u6027\u60a3\u6709\u808c\u5c11\u75c7\uff0c\u7531\u65bc\u808c\u5c11\u75c7\u4f1a\u5bfc\u81f4\u808c\u8089\u529b\u91cf\u51cf\u5c11\uff0c\u4e0b\u80a2\u529f\u80fd\u53d8\u5dee\uff0c\u56e0\u6b64\u8f83\u6613\u8dcc\u5012\u4e36\u589e\u52a0\u5931\u80fd\u98ce\u9669\uff0c\u5927\u5e45\u63d0\u5347\u8001\u5e74\u5f8c\u5931\u80fd\u7684\u6bd4\u7387… \u7f8e\u56fd\u54c8\u4f5b\u5927\u5b66\u8870\u8001\u751f\u7269\u5b66\u4e2d\u5fc3\u7684\u79d1\u7814\u56e2\u961f\u53d1\u73b0\uff0cNMN\u4ecb\u5165\u7684\u8001\u5e74\u5c0f\u9f20\u53ef\u663e\u7740\u6539\u5584\u808c\u8089\u529f\u80fd\u3002\u4f8b\u5982\uff0c\u7528 NMN\uff08500 mg\/\u5929 \uff0c\u8fde\u7eed 7 \u5929\uff09\u4ecb\u5165\u7684\u8001\u5e74\u5c0f\u9f20\uff0c\u901a\u8fc7\u589e\u52a0\u7c92\u7ebf\u4f53\u529f\u80fd\u4e36\u589e\u52a0 ATP \u4ea7\u751f\u4e36\u51cf\u5c11\u708e\u75c7\u548c\u5c06\u7cd6\u9175\u89e3 II \u578b\u808c\u7ea4\u7ef4\u8f6c\u6362\u4e3a\u66f4\u591a\u6c27\u5316\u7ea4\u7ef4\u7c7b\u578b\u3002 \u6b64\u79d1\u7814\u6210\u679c\u53d1\u8868\u5728\u4e09\u5927\u9876\u7ea7\u671f\u520a\u4e4b\u4e00 Cell Gomes AP, Price NL, Ling AJ, Moslehi JJ, Montgomery MK, Rajman L, White JP, Teodoro JS, Wrann CD, Hubbard BP, Mercken EM, Palmeira CM, de Cabo R, Rolo AP, Turner N, Bell EL, Sinclair DA. Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. […]<\/p>\n

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