{"id":19240,"date":"2022-10-22T13:00:46","date_gmt":"2022-10-22T13:00:46","guid":{"rendered":"http:\/\/johnhealth.blog\/ch\/?p=19240"},"modified":"2022-10-22T13:02:14","modified_gmt":"2022-10-22T13:02:14","slug":"%e3%80%90%e7%a7%91%e6%8a%80%e6%96%87%e7%8c%ae%e3%80%91%e6%97%a5%e6%9c%ac%e7%a0%94%e7%a9%b6%e8%a1%a8%e6%98%8e-nmn-%e6%b3%a8%e5%b0%84%e5%8f%af%e9%99%8d%e4%bd%8e%e5%81%a5%e5%ba%b7%e4%b8%aa%e4%bd%93","status":"publish","type":"post","link":"http:\/\/johnhealth.blog\/ch\/?p=19240","title":{"rendered":"\u3010\u79d1\u6280\u6587\u732e\u3011\u65e5\u672c\u7814\u7a76\u8868\u660e NMN \u6ce8\u5c04\u53ef\u964d\u4f4e\u5065\u5eb7\u4e2a\u4f53\u7684\u8840\u8102\u542b\u91cf"},"content":{"rendered":"<p>\u65e5\u672c\u7814\u7a76\u8868\u660e NMN \u6ce8\u5c04\u53ef\u964d\u4f4e\u5065\u5eb7\u4e2a\u4f53\u7684\u8840\u8102\u542b\u91cf<\/p>\n<p>\u5b89\u5168\u6709\u6548\u5730\u4e3a\u5065\u5eb7\u4e2a\u4f53\u6ce8\u5c04 NMN \u53ef\u964d\u4f4e\u8840\u8102\uff08\u7518\u6cb9\u4e09\u916f\uff09\u542b\u91cf\u5e76\u589e\u52a0 NAD+ \u6c34\u5e73<\/p>\n<p>Published: 12:38 p.m. PST Sep 13, 2022 | Updated: 11:48 am PST Sep 26, 2022<\/p>\n<p>\u91cd\u5927\u4eae\u70b9<\/p>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li>\u5355\u6b21\u6ce8\u5c04 NMN \u53ef\u4f7f\u8840\u8102\u542b\u91cf\u964d\u4f4e\u7ea6 75%\u3002<\/li>\n<li>\u5c3d\u7ba1\u7ed5\u8fc7\u4e86\u8eab\u4f53\u7684\u89e3\u6bd2\u5242\u2014\u2014\u809d\u810f\uff0cNMN \u6ce8\u5c04\u6db2\u53ef\u4ee5\u5b89\u5168\u4ee3\u8c22\uff0c\u4e0d\u4f1a\u5bf9\u5fc3\u810f\u4e36\u80be\u810f\u6216\u80f0\u810f\u9020\u6210\u660e\u663e\u7684\u635f\u5bb3\u3002<\/li>\n<li>\u6ce8\u5c04\u5c06\u8840\u6db2 NAD+ \u6c34\u5e73\u63d0\u9ad8\u7ea6 20%\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><!--more--><\/p>\n<p>\u556e\u9f7f\u52a8\u7269\u7814\u7a76\u8868\u660e\uff0c\u8865\u5145\u70df\u9170\u80fa\u5355\u6838\u82f7\u9178 (NMN) \u53ef\u4ee5\u9006\u8f6c\u4e0e\u5e74\u9f84\u76f8\u5173\u7684\u75be\u75c5\uff0c\u800c\u4eba\u7c7b\u7814\u7a76\u8868\u660e\u5b83\u53ef\u4ee5\u6539\u5584\u80f0\u5c9b\u7d20\u654f\u611f\u6027\u548c\u808c\u8089\u529f\u80fd\u3002 \u56e0\u6b64\uff0c\u4f5c\u4e3a\u4e00\u79cd\u6f5c\u5728\u7684\u6297\u8870\u8001\u63aa\u65bd\uff0c\u65e5\u672c\u7684\u51e0\u5bb6\u8bca\u6240\u5df2\u7ecf\u5f00\u59cb\u901a\u8fc7\u9759\u8109\u6ce8\u5c04\u6765\u7ba1\u7406 NMN\u3002 \u867d\u7136\u53e3\u670d NMN \u5df2\u88ab\u8bc1\u660e\u662f\u5b89\u5168\u7684\uff0c\u4f46\u9759\u8109\u6ce8\u5c04 NMN \u7684\u5b89\u5168\u6027\u5c1a\u672a\u5f97\u5230\u8bc1\u5b9e\u3002 \u5f53\u76f4\u63a5\u6ce8\u5c04\u5230\u8840\u6db2\u4e2d\u65f6\uff0cNMN \u4f1a\u7ed5\u8fc7\u8eab\u4f53\u7684\u4e2d\u67a2\u89e3\u6bd2\u5242\u2014\u809d\u810f\u3002 \u4eba\u4eec\u8d8a\u6765\u8d8a\u62c5\u5fc3\u5982\u679c\u6ca1\u6709\u809d\u810f\u8fc7\u6ee4\uff0cNMN \u53ef\u80fd\u4f1a\u5bf9\u5fc3\u810f\u4e36\u80f0\u810f\u548c\/\u6216\u80be\u810f\u9020\u6210\u635f\u5bb3\u3002<\/p>\n<p>\u65e5\u672c\u5175\u5e93\u533b\u79d1\u5927\u5b66\u7684 Gotoh \u53ca\u5176\u540c\u4e8b\u5728\u5b66\u672f\u671f\u520a \u300aCureus\u300b \u4e0a\u53d1\u8868\u6587\u7ae0\u8868\u660e\uff0c<a href=\"https:\/\/www.cureus.com\/articles\/112244-nicotinamide-mononucleotide-is-safely-metabolized-and-significantly-reduces-blood-triglyceride-levels-in-healthy-individuals\">NMN \u53ef\u4ee5\u5b89\u5168\u4ee3\u8c22\uff0c\u5e76\u5728\u6ce8\u5c04\u65f6\u663e\u7740\u964d\u4f4e\u8840\u8102\uff08\u7518\u6cb9\u4e09\u916f\uff09\u6c34\u5e73<\/a>\u3002 \u6b64\u5916\uff0c\u6ce8\u5c04 NMN \u53ef\u663e\u7740\u63d0\u9ad8\u957f\u5bff\u5206\u5b50\u70df\u9170\u80fa\u817a\u560c\u5464\u4e8c\u6838\u82f7\u9178 (NAD+) \u7684\u8840\u6db2\u6c34\u5e73\u3002 \u6709\u8da3\u7684\u662f\uff0c\u8fc4\u4eca\u4e3a\u6b62\u8fd8\u6ca1\u6709\u5176\u4ed6\u4eba\u4f53\u7814\u7a76\u8868\u660e NMN \u53ef\u4ee5\u964d\u4f4e\u8840\u6db2\u4e2d\u7684\u7518\u6cb9\u4e09\u916f\u6c34\u5e73\uff0c\u8fd9\u53ef\u80fd\u662f\u56e0\u4e3a\u4f7f\u7528\u4e86\u53e3\u670d\u8865\u5145\u5242\u3002 \u8fd9\u4e9b\u53d1\u73b0\u8868\u660e\uff0cNMN \u6ce8\u5c04\u53ef\u4ee5\u5b89\u5168\u5730\u4ee3\u8c22\uff0c\u5e76\u53ef\u80fd\u6709\u52a9\u65bc\u964d\u4f4e\u8840\u6db2\u4e2d\u7684\u7518\u6cb9\u4e09\u916f\u6c34\u5e73\u3002<\/p>\n<p><strong><span style=\"color: #ff0000;\">NMN \u6ce8\u5c04\u53ef\u964d\u4f4e\u8840\u8102\u5e76\u589e\u52a0 NAD+<\/span><\/strong><\/p>\n<p>\u4e3a\u4e86\u6d4b\u91cf NMN \u6ce8\u5c04\u662f\u5426\u80fd\u5e26\u6765\u4ee3\u8c22\u76ca\u5904\uff0cGotoh \u53ca\u5176\u540c\u4e8b\u4e3a 10 \u540d\u5065\u5eb7\u4eba\u4f53\u53d7\u8bd5\u8005\uff08\u5e74\u9f84 20-70 \u5c81\uff09\u9759\u8109\u6ce8\u5c04\u4e86 300 mg NMN \u5e76\u8fdb\u884c\u4e86\u8840\u6db2\u5206\u6790\u3002 \u5c3d\u7ba1 NMN \u6ce8\u5c04\u5bf9\u80c6\u56fa\u9187\u6ca1\u6709\u5f71\u54cd\uff0c\u4f46\u5b83\u4f7f\u8840\u6db2\u7518\u6cb9\u4e09\u916f\u964d\u4f4e\u4e86\u7ea6 75%\uff08\u4e09\u5c0f\u65f6\u5f8c\u4ece ~80 mg\/dL \u964d\u81f3 ~20 mg\/dL\uff09\u3002 \u6ca1\u6709\u4f7f\u7528\u53e3\u670d NMN \u4ecb\u5165\u7684\u7814\u7a76\u8868\u660e\u7518\u6cb9\u4e09\u916f\u6c34\u5e73\u964d\u4f4e\uff0c\u8fd9\u8868\u660e NMN \u6ce8\u5c04\u5177\u6709\u72ec\u7279\u7684\u76ca\u5904\u3002 \u7518\u6cb9\u4e09\u916f\u6c34\u5e73\u5347\u9ad8\u4e0e\u8102\u80aa\u809d\u75be\u75c5\u548c II \u578b\u7cd6\u5c3f\u75c5\u6709\u5173\uff0c\u56e0\u6b64 NMN \u6ce8\u5c04\u53ef\u80fd\u63d0\u4f9b\u5bf9\u6297\u8fd9\u4e9b\u4e0e\u5e74\u9f84\u76f8\u5173\u7684\u75be\u75c5\u7684\u65b9\u6cd5\u3002<\/p>\n<div class=\"s-block-item s-repeatable-item s-block-sortable-item s-blog-post-section blog-section\">\n<div class=\"container\">\n<div class=\"sixteen columns\">\n<div class=\"s-blog-section-inner\">\n<div class=\"s-component s-image\">\n<div>\n<div class=\"s-component-content\">\n<div class=\"s-img-wrapper\"><img decoding=\"async\" class=\"crop-default\" title=\"\" src=\"https:\/\/custom-images.strikinglycdn.com\/res\/hrscywv4p\/image\/upload\/c_limit,fl_lossy,h_9000,w_1200,f_auto,q_auto\/3160820\/107200_42941.png\" alt=\"\" data-description=\"\" data-image-link=\"javascript:void(0);\" \/><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"s-block-item s-repeatable-item s-block-sortable-item s-blog-post-section s-narrow-margin blog-section\">\n<div class=\"container\">\n<div class=\"sixteen columns\">\n<div class=\"s-blog-section-inner\">\n<div class=\"s-component s-text\">\n<div class=\"\">\n<div class=\"s-component-content s-font-body\">\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"s-block-item s-repeatable-item s-block-sortable-item s-blog-post-section s-narrow-margin blog-section\">\n<div class=\"container\">\n<div class=\"sixteen columns\">\n<div class=\"s-blog-section-inner\">\n<div class=\"s-component s-text\">\n<div class=\"\">\n<div class=\"s-component-content s-font-body\">\n<p><a href=\"https:\/\/www.cureus.com\/articles\/112244-nicotinamide-mononucleotide-is-safely-metabolized-and-significantly-reduces-blood-triglyceride-levels-in-healthy-individuals\" target=\"_blank\" rel=\"noopener\" data-type=\"\">(Kimura et al., 2022 |<\/a>\u00a0<a href=\"https:\/\/www.cureus.com\/articles\/112244-nicotinamide-mononucleotide-is-safely-metabolized-and-significantly-reduces-blood-triglyceride-levels-in-healthy-individuals\" target=\"_blank\" rel=\"noopener\" data-type=\"\"><em>Cureus<\/em><\/a><a href=\"https:\/\/www.cureus.com\/articles\/112244-nicotinamide-mononucleotide-is-safely-metabolized-and-significantly-reduces-blood-triglyceride-levels-in-healthy-individuals\" target=\"_blank\" rel=\"noopener\" data-type=\"\">)<\/a> \u00a0<span style=\"font-size: 1rem;\">\u6ce8\u5c04 NMN \u53ef\u663e\u7740\u964d\u4f4e\u8840\u8102\uff08\u7518\u6cb9\u4e09\u916f\uff09\u542b\u91cf\u3002 \u7518\u6cb9\u4e09\u916f (TG) \u6c34\u5e73\u5728 NMN \u6ce8\u5c04\u5f8c\u4e09\u5c0f\u65f6\u4e0b\u964d\u81f3\u5176\u539f\u59cb\u503c\u7684\u56db\u5206\u4e4b\u4e00\u5de6\u53f3\uff0c\u5e76\u5728\u4e94\u5c0f\u65f6\u5f8c\u4e0a\u5347\u81f3\u5176\u539f\u59cb\u503c\u7684\u4e00\u534a\u5de6\u53f3\u3002<\/span><\/p>\n<p><span style=\"font-size: 1rem;\">\u4e3a\u4e86\u4e86\u89e3 NMN \u7684\u76ca\u5904\u662f\u5426\u6765\u81ea\u65bc\u589e\u52a0\u957f\u5bff\u5206\u5b50 NAD+ \u7684\u6c34\u5e73\uff0c\u65e5\u672c\u7814\u7a76\u4eba\u5458\u5206\u6790\u4e86\u8840\u6db2\u4e2d\u7684 NAD+ \u6c34\u5e73\u3002 \u7814\u7a76\u5c0f\u7ec4\u53d1\u73b0\uff0c\u6ce8\u5c04 NMN \u5f8c 5 \u5c0f\u65f6\uff0cNAD+ \u6c34\u5e73\u4f1a\u589e\u52a0\u7ea6 20%\u3002 \u6ce8\u5c04\u5f8c\u4e09\u5c0f\u65f6\u89c2\u5bdf\u5230 NAD+ \u542b\u91cf\u4e0b\u964d\uff0c\u7814\u7a76\u5c0f\u7ec4\u5bf9\u6b64\u6ca1\u6709\u5408\u7406\u7684\u89e3\u91ca\u3002 \u8fd9\u4e9b\u53d1\u73b0\u8868\u660e\uff0cNMN \u7684\u5f71\u54cd\uff0c\u5305\u62ec\u964d\u4f4e\u7518\u6cb9\u4e09\u916f\u6c34\u5e73\uff0c\u6765\u81ea\u65bc\u63d0\u9ad8 NAD+ \u6c34\u5e73\u3002<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"s-block-item s-repeatable-item s-block-sortable-item s-blog-post-section blog-section\">\n<div class=\"container\">\n<div class=\"sixteen columns\">\n<div class=\"s-blog-section-inner\">\n<div class=\"s-component s-image\">\n<div>\n<div class=\"s-component-content\">\n<div><\/div>\n<div class=\"s-img-wrapper\"><img decoding=\"async\" class=\"crop-default\" title=\"\" src=\"https:\/\/custom-images.strikinglycdn.com\/res\/hrscywv4p\/image\/upload\/c_limit,fl_lossy,h_9000,w_1200,f_auto,q_auto\/3160820\/998183_390653.png\" alt=\"\" data-description=\"\" data-image-link=\"javascript:void(0);\" \/><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"s-block-item s-repeatable-item s-block-sortable-item s-blog-post-section s-narrow-margin blog-section\">\n<div class=\"container\">\n<div class=\"sixteen columns\">\n<div class=\"s-blog-section-inner\">\n<div class=\"s-component s-text\">\n<div class=\"\">\n<div class=\"s-component-content s-font-body\">\n<p><a href=\"https:\/\/www.cureus.com\/articles\/112244-nicotinamide-mononucleotide-is-safely-metabolized-and-significantly-reduces-blood-triglyceride-levels-in-healthy-individuals\" target=\"_blank\" rel=\"noopener\" data-type=\"\">(Kimura et al., 2022 |<\/a>\u00a0<a href=\"https:\/\/www.cureus.com\/articles\/112244-nicotinamide-mononucleotide-is-safely-metabolized-and-significantly-reduces-blood-triglyceride-levels-in-healthy-individuals\" target=\"_blank\" rel=\"noopener\" data-type=\"\"><em>Cureus<\/em><\/a><a href=\"https:\/\/www.cureus.com\/articles\/112244-nicotinamide-mononucleotide-is-safely-metabolized-and-significantly-reduces-blood-triglyceride-levels-in-healthy-individuals\" target=\"_blank\" rel=\"noopener\" data-type=\"\">)<\/a> <span style=\"font-size: 1rem;\">NMN \u6ce8\u5c04\u53ef\u4f7f\u8840\u6db2\u4e2d\u7684 NAD+ \u5347\u9ad8\u7ea6 20%\u3002 NMN \u6ce8\u5c04\u5f8c\u4e24\u5c0f\u65f6\uff0c\u8840\u6db2\u4e2d\u7684\u603b NAD+ \u6c34\u5e73\u589e\u52a0\u7ea6 20%\u3002 \u7531\u65bc\u672a\u77e5\u539f\u56e0\uff0cNAD+ \u6c34\u5e73\u5728\u4e09\u5c0f\u65f6\u5f8c\u4e0b\u964d\uff0c\u7136\u5f8c\u518d\u6b21\u4e0a\u5347\u3002<\/span><\/p>\n<p><span style=\"font-size: 1rem;\">\u201c\u6211\u4eec\u7684\u4e34\u5e8a\u7814\u7a76\u8868\u660e\uff0c\u4eba\u7c7b\u53ef\u4ee5\u8010\u53d7 300 mg NMN \u7ed9\u836f\uff0c\u56e0\u4e3a\u5b83\u5728\u9759\u8109\u5185\u6ce8\u5c04\u65f6\u4e0d\u4f1a\u5bf9\u8840\u7ec6\u80de\u4e36\u809d\u810f\u4e36\u80f0\u810f\u4e36\u5fc3\u810f\u548c\u80be\u810f\u9020\u6210\u663e\u7740\u635f\u5bb3\uff0c\u5e76\u6709\u6548\u589e\u52a0\u8840\u7ec6\u80de\u4e2d NAD+ \u7684\u542b\u91cf\uff0c\u201dGotoh\u548c\u540c\u4e8b\u8868\u793a\u3002<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>&nbsp;<\/p>\n<p><strong><span style=\"color: #ff0000;\">\u6ce8\u5c04 NMN \u53ef\u80fd\u4f1a\u5e26\u6765\u53e3\u670d\u6240\u6ca1\u6709\u7684\u597d\u5904<\/span><\/strong><\/p>\n<p>Gotho \u53ca\u5176\u540c\u4e8b\u7684\u7814\u7a76\u8868\u660e\uff0c\u5c3d\u7ba1\u7ed5\u8fc7\u809d\u810f\uff0c\u9759\u8109\u5185\u65bd\u7528\u7684 NMN \u4ecd\u53ef\u4ee5\u5b89\u5168\u5730\u4ee3\u8c22\u3002 \u8fd9\u79cd\u7ed9\u836f\u9014\u5f84\u53ef\u80fd\u4f1a\u83b7\u5f97\u53e3\u670d NMN \u65e0\u6cd5\u63d0\u4f9b\u7684\u597d\u5904\uff0c\u4f8b\u5982\u964d\u4f4e\u7518\u6cb9\u4e09\u916f\u6c34\u5e73\u3002 \u672a\u6765\u7684\u7814\u7a76\u5e94\u8be5\u68c0\u67e5\u9759\u8109\u6ce8\u5c04 NMN \u5982\u4f55\u5f71\u54cd\u5176\u4ed6\u4e0e\u5e74\u9f84\u76f8\u5173\u7684\u75be\u75c5\uff0c\u5982\u808c\u8089\u8870\u9000\u4e36\u80f0\u5c9b\u7d20\u4e0d\u654f\u611f\u4ee5\u53ca\u76ae\u80a4\u7b49\u5668\u5b98\u4e2d NAD+ \u6c34\u5e73\u7684\u964d\u4f4e\u3002 NMN \u6ce8\u5c04\u5242\u53ef\u80fd\u63d0\u4f9b\u4ee5\u524d\u7684\u4e34\u5e8a\u8bd5\u9a8c\u5728\u53e3\u670d\u6cbb\u7597\u4e2d\u6ca1\u6709\u53d1\u73b0\u7684\u597d\u5904\u3002 \u6b64\u5916\uff0c\u5e94\u5728\u8f83\u957f\u65f6\u95f4\u5185\u6d4b\u91cf NMN \u6ce8\u5c04\u7684\u6548\u679c\u3002<\/p>\n<p>\u53c2\u8003\u6587\u732e<\/p>\n<p>Kimura S, Ichikawa M, Sugawara S, et al. (September 05, 2022) Nicotinamide Mononucleotide Is Safely Metabolized and Significantly Reduces Blood Triglyceride Levels in Healthy Individuals. Cureus 14(9): e28812. doi:10.7759\/cureus.28812<\/p>\n<p>\u6587\u7ae0\u6765\u6e90<\/p>\n<p>https:\/\/www.nmn.com\/news\/nmn-injections-reduce-blood-fat-content<\/p>\n<div class=\"pvc_clear\"><\/div>\n<p id=\"pvc_stats_19240\" class=\"pvc_stats all  \" data-element-id=\"19240\" style=\"\"><i class=\"pvc-stats-icon medium\" aria-hidden=\"true\"><svg aria-hidden=\"true\" focusable=\"false\" data-prefix=\"far\" data-icon=\"chart-bar\" role=\"img\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\" class=\"svg-inline--fa fa-chart-bar fa-w-16 fa-2x\"><path fill=\"currentColor\" d=\"M396.8 352h22.4c6.4 0 12.8-6.4 12.8-12.8V108.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v230.4c0 6.4 6.4 12.8 12.8 12.8zm-192 0h22.4c6.4 0 12.8-6.4 12.8-12.8V140.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v198.4c0 6.4 6.4 12.8 12.8 12.8zm96 0h22.4c6.4 0 12.8-6.4 12.8-12.8V204.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v134.4c0 6.4 6.4 12.8 12.8 12.8zM496 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