{"id":18916,"date":"2022-09-05T02:08:47","date_gmt":"2022-09-05T02:08:47","guid":{"rendered":"http:\/\/johnhealth.blog\/ch\/?p=18916"},"modified":"2022-09-05T03:02:16","modified_gmt":"2022-09-05T03:02:16","slug":"%e3%80%90%e7%a7%91%e6%8a%80%e6%96%87%e7%8c%ae%e3%80%91%e7%a0%94%e7%a9%b6%e4%ba%ba%e5%91%98%e5%8f%91%e7%8e%b0%ef%bc%8c12-%e5%91%a8%e7%9a%84-nmn-%e8%a1%a5%e5%85%85%e5%89%82%e5%8f%af%e4%bd%bf-nad","status":"publish","type":"post","link":"http:\/\/johnhealth.blog\/ch\/?p=18916","title":{"rendered":"\u3010\u79d1\u6280\u6587\u732e\u3011\u7814\u7a76\u4eba\u5458\u53d1\u73b0\uff0c12 \u5468\u7684 NMN \u8865\u5145\u5242\u53ef\u4f7f NAD+ \u6c34\u5e73\u589e\u52a0\u4e00\u500d\u4ee5\u4e0a\u5e76\u6539\u5584\u808c\u8089\u529f\u80fd"},"content":{"rendered":"<p>\u65e5\u672c\u79d1\u5b66\u5bb6\u8868\u660e\uff0c\u7ed9\u8001\u5e74\u7537\u6027\u670d\u7528 NMN \u53ef\u4f7f\u8840\u6db2\u4e2d\u7684 NAD+ \u6c34\u5e73\u589e\u52a0\u4e00\u500d\u4ee5\u4e0a\uff0c\u5e76\u63d0\u9ad8\u6b65\u884c\u901f\u5ea6\u548c\u63e1\u529b\u3002<\/p>\n<p>\u91cd\u5927\u4eae\u70b9<\/p>\n<ul>\n<li>\u6bcf\u5929\u670d\u7528 250 \u6beb\u514b NMN\uff0c\u6301\u7eed 12 \u5468\uff0c\u4f7f 65 \u5c81\u4ee5\u4e0a\u5065\u5eb7\u7537\u6027\u8840\u6db2\u4e2d NAD+ \u6c34\u5e73\u7684\u589e\u52a0\u4e00\u500d\u591a\u3002<\/li>\n<li>NMN\u7684\u8865\u5145\u65b9\u6848\u63d0\u9ad8\u4e86\u8001\u5e74\u7537\u6027\u7684\u6b65\u884c\u901f\u5ea6\u548c\u63e1\u529b\u3002<\/li>\n<li>\u8fd9\u4e9b\u53d1\u73b0\u8868\u660e\uff0c\u8865\u5145 NMN \u53ef\u7528\u65bc\u6539\u5584\u4e0e\u8870\u8001\u76f8\u5173\u7684\u808c\u8089\u9000\u5316\u3002<\/li>\n<\/ul>\n<p><!--more--><\/p>\n<p><strong><span style=\"color: #ff6600;\">\u70df\u9170\u80fa\u817a\u560c\u5464\u4e8c\u6838\u82f7\u9178 (NAD+)\u00a0<\/span><\/strong>\u662f\u7ec6\u80de\u80fd\u91cf\u4ea7\u751f\u4e36DNA \u4fee\u590d\u548c\u514d\u75ab\u529f\u80fd\u7684\u91cd\u8981\u5206\u5b50\u3002 \u8bb8\u591a\u4e0e\u8870\u8001\u76f8\u5173\u7684\u5fc3\u8840\u7ba1\u4e36\u795e\u7ecf\u4e36\u4ee3\u8c22\u548c\u808c\u8089\u75be\u75c5\u4e0e\u556e\u9f7f\u52a8\u7269\u548c\u4eba\u7c7b\u7684 NAD+ \u6c34\u5e73\u4e0b\u964d\u6709\u5173\u3002 \u8865\u5145\u5176\u524d\u4f53\u70df\u9170\u80fa\u5355\u6838\u82f7\u9178 (NMN)\u00a0\u53ef\u6062\u590d NAD+ \u6c34\u5e73\u5e76\u51cf\u8f7b\u556e\u9f7f\u52a8\u7269\u4e0e\u8870\u8001\u76f8\u5173\u7684\u8eab\u4f53\u8870\u9000\u3002 \u5269\u4e0b\u7684\u4e00\u4e2a\u4e3b\u8981\u95ee\u9898\u662f\uff0c\u7528 NMN \u63d0\u9ad8 NAD+ \u6c34\u5e73\u662f\u5426\u53ef\u4ee5\u4e3a\u4eba\u7c7b\u505a\u540c\u6837\u7684\u4e8b\u60c5\u3002<\/p>\n<p>\u4e1c\u4eac\u5927\u5b66\u7684 Yamauchi \u53ca\u5176\u540c\u4e8b\u5728\u5b66\u672f\u671f\u520a \u300a<strong><span style=\"color: #0000ff;\">\u81ea\u7136\u8870\u8001<\/span><\/strong>\u300b(Nature Aging) \u4e0a\u53d1\u8868\u8bba\u6587\u8868\u660e\uff0c\u8865\u5145\u00a012 \u5468\u7684\u00a0NMN \u53ef\u4f7f\u8840\u6db2\u4e2d\u7684 NAD+ \u6c34\u5e73\u589e\u52a0\u4e00\u500d\u4ee5\u4e0a\uff0c\u5e76<strong><span style=\"color: #ff0000;\">\u63d0\u9ad8\u8001\u5e74\u5065\u5eb7\u7537\u6027\u7684\u6b65\u884c\u901f\u5ea6<\/span><\/strong>\u3002 \u8fd9\u4e9b\u53d1\u73b0\u6982\u62ec\u4e86\u5148\u524d\u7814\u7a76\u7684\u6570\u636e\uff0c\u8868\u660e\u8865\u5145 NMN \u53ef\u63d0\u9ad8\u4eba\u7c7b\u8840\u6db2\u4e2d\u7684 NAD+ \u6c34\u5e73\u3002 \u6b64\u5916\uff0c\u8be5\u7814\u7a76\u8868\u660e\uff0c\u8865\u5145 NMN \u53ef\u80fd\u4f1a\u63d0\u4f9b\u51cf\u8f7b\u808c\u8089\u51cf\u5c11\u75c7\u7684\u65b9\u6cd5\u3002<\/p>\n<p>NMN \u4f7f\u8840\u6db2 NAD+ \u589e\u52a0\u4e00\u500d\u4ee5\u4e0a\u5e76\u63d0\u9ad8\u6b65\u884c\u901f\u5ea6<\/p>\n<p>\u7531\u65bc\u556e\u9f7f\u52a8\u7269\u7814\u7a76\u8868\u660e\uff0c\u7528 NMN \u63d0\u9ad8 NAD+ \u4e0e\u51cf\u8f7b\u4e0e\u8870\u8001\u76f8\u5173\u7684\u751f\u7406\u8870\u9000\u4e4b\u95f4\u5b58\u5728\u6709\u76ca\u7684\u76f8\u5173\u6027\uff0c\u56e0\u6b64\u65e5\u672c\u7814\u7a76\u4eba\u5458\u6d4b\u91cf\u4e86 NMN \u5bf9\u8840\u6db2 NAD+ \u7684\u5f71\u54cd\u3002 \u4ed6\u4eec\u53d1\u73b0\u8865\u5145 NMN \u4f1a\u4f7f\u8001\u5e74\u7537\u6027\u8840\u6db2\u4e2d\u7684 NAD+ \u6d53\u5ea6\u589e\u52a0\u4e00\u500d\u4ee5\u4e0a\u3002 \u66f4\u91cd\u8981\u7684\u662f\uff0cNAD+ \u5408\u6210\u4ee3\u8c22\u7269\u5982\u83f8\u9178\u5355\u6838\u82f7\u9178 (NAMN) \u7684\u6c34\u5e73\u4f1a\u968f\u7740 12 \u5468\u7684\u8865\u5145\u800c\u589e\u52a0\u3002 \u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u957f\u671f\u8865\u5145 NMN \u53ef\u589e\u52a0 NAD+ \u7684\u5408\u6210\u5e76\u63d0\u9ad8\u5176\u5728\u8840\u6db2\u4e2d\u7684\u6c34\u5e73\u3002<\/p>\n<div class=\"s-block-item s-repeatable-item s-block-sortable-item s-blog-post-section blog-section\">\n<div class=\"container\">\n<div class=\"sixteen columns\">\n<div class=\"s-blog-section-inner\">\n<div class=\"s-component s-image\">\n<div class=\"s-component-content\">\n<div class=\"s-img-wrapper\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-18917\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2022\/09\/75153_691618.webp\" alt=\"\" width=\"712\" height=\"585\" srcset=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2022\/09\/75153_691618.webp 712w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2022\/09\/75153_691618-300x246.webp 300w\" sizes=\"auto, (max-width: 712px) 100vw, 712px\" \/><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"s-block-item s-repeatable-item s-block-sortable-item s-blog-post-section blog-section\">\n<div class=\"container\">\n<div class=\"sixteen columns\">\n<div class=\"s-blog-section-inner\">\n<div class=\"s-component s-text\">\n<div class=\"\">\n<div class=\"s-component-content s-font-body\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35927255\/\" target=\"_blank\" rel=\"noopener\" data-type=\"\">(Igarashi et al., 2022 |<\/a>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35927255\/\" target=\"_blank\" rel=\"noopener\" data-type=\"\"><em>NPJ Aging<\/em><\/a><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35927255\/\" target=\"_blank\" rel=\"noopener\" data-type=\"\">)<\/a>\u00a0\u8865\u5145 NMN 12 \u5468\u53ef\u4f7f\u8840\u6db2 NAD+ \u6c34\u5e73\u589e\u52a0\u4e00\u500d\u4ee5\u4e0a\u3002<\/p>\n<p>\u4e3a\u4e86\u786e\u5b9a\u589e\u52a0\u7684 NAD+ \u6c34\u5e73\u662f\u5426\u80fd\u6539\u5584\u808c\u8089\u6027\u80fd\uff0cYamauchi \u53ca\u5176\u540c\u4e8b\u68c0\u67e5\u4e86\u6b65\u884c\u901f\u5ea6\u548c\u63e1\u529b\u3002 \u7814\u7a76\u5c0f\u7ec4\u53d1\u73b0\uff0c\u5728\u8865\u5145 NMN \u7684\u7b2c 6 \u5468\u548c\u7b2c 12 \u5468\u65f6\uff0c\u6b65\u884c\u901f\u5ea6\u548c\u5de6\u624b\u63e1\u529b\u663e\u7740\u63d0\u9ad8\u3002 \u7136\u800c\uff0c\u53f3\u624b\u63e1\u529b\u5e76\u6ca1\u6709\u63d0\u9ad8\u3002 \u8fd9\u610f\u5473\u7740\u901a\u8fc7\u8865\u5145 NMN \u6765\u589e\u5f3a\u8eab\u4f53\u673a\u80fd\u53ef\u80fd\u4f1a\u63d0\u4f9b\u4e00\u79cd\u51cf\u8f7b\u4e0e\u8870\u8001\u76f8\u5173\u7684\u808c\u8089\u65e0\u529b\u548c\u8010\u529b\u7684\u65b9\u6cd5\u3002<\/p>\n<p>\u201c\u5728\u8fd9\u9879\u7814\u7a76\u4e2d\uff0c\u6211\u4eec\u62a5\u544a\u8bf4\uff0c\u6bcf\u5929\u957f\u671f\u53e3\u670d\u8865\u5145 250 mg NMN \u662f\u5b89\u5168\u7684\uff0c\u5e76\u4e14\u662f\u4fc3\u8fdb\u5065\u5eb7\u8001\u5e74\u7537\u6027 NAD+ \u4ee3\u8c22\u7684\u4e00\u79cd\u8010\u53d7\u6027\u826f\u597d\u4e14\u6709\u6548\u7684\u7b56\u7565\uff0c\u201dYamauchi \u53ca\u5176\u540c\u4e8b\u8bf4\u3002 \u201c\u6b64\u5916\uff0c\u6211\u4eec\u5bf9\u8865\u5145 NMN \u5bf9\u751f\u7406\u529f\u80fd\u5f71\u54cd\u7684\u63a2\u7d22\u6027\u5206\u6790\u8868\u660e\uff0cNMN \u53ef\u4ee5\u63d0\u9ad8\u808c\u8089\u529b\u91cf\uff0c\u8fd9\u662f\u8870\u8001\u7684\u91cd\u8981\u4e34\u5e8a\u6307\u6807\u3002\u201d<\/p>\n<p><strong><span style=\"color: #ff6600;\">NMN \u4f1a\u589e\u52a0\u5176\u4ed6\u5668\u5b98\u7684 NAD+ \u6c34\u5e73\u5417\uff1f<\/span><\/strong><\/p>\n<p>\u8be5\u7814\u7a76\u7684\u4e00\u4e2a\u9650\u5236\u662f\u5b83\u6ca1\u6709\u68c0\u67e5\u8865\u5145 NMN \u662f\u5426\u4f1a\u589e\u52a0\u5927\u8111\u4e36\u809d\u810f\u6216\u80be\u810f\u7b49\u5668\u5b98\u4e2d\u7684 NAD+\uff0c\u8fd9\u5bf9\u65bc\u5f04\u6e05\u695a NMN \u662f\u5426\u53ef\u4ee5\u63d0\u4f9b\u4e00\u79cd\u65b9\u6cd5\u6765\u5bf9\u6297\u4e0e\u8fd9\u4e9b\u76f8\u5173\u7684\u591a\u79cd\u4e0e\u8870\u8001\u76f8\u5173\u7684\u75be\u75c5\u81f3\u5173\u91cd\u8981 \u5668\u5b98\u3002 \u7136\u800c\uff0cYamauchi \u53ca\u5176\u540c\u4e8b\u786e\u5b9e\u6d4b\u91cf\u4e86\u611f\u89c9\u548c\u8ba4\u77e5\u529f\u80fd\uff0c\u4ee5\u53ca\u809d\u810f\u8102\u80aa\u91cf\u548c\u80f0\u5c9b\u7d20\u654f\u611f\u6027\uff0c\u4f46\u4ed6\u4eec\u5728\u670d\u7528 NMN\u00a0\u65f6\u6ca1\u6709\u53d1\u73b0\u4efb\u4f55\u5dee\u5f02\u3002<\/p>\n<p>\u8fd9\u9879\u7814\u7a76\u53ef\u80fd\u53ea\u662f\u53d1\u73b0 NMN \u8865\u5145\u5242\u4e3a\u8001\u5e74\u4eba\u5e26\u6765\u7684\u597d\u5904\u7684\u51b0\u5c71\u4e00\u89d2\u3002 \u9664\u4e86\u808c\u8089\u529f\u80fd\uff0c\u672a\u6765\u7684\u7814\u7a76\u8fd8\u9700\u8981\u68c0\u67e5 NMN \u5bf9\u591a\u79cd\u4e0e\u8870\u8001\u76f8\u5173\u7684\u75be\u75c5\u7684\u5f71\u54cd\uff0c\u8fd9\u4e9b\u4e34\u5e8a\u8bd5\u9a8c\u53ef\u80fd\u9700\u8981\u5ef6\u957f 12 \u5468\u4ee5\u4e0a\u624d\u80fd\u53d1\u73b0\u6709\u610f\u4e49\u7684\u5f71\u54cd\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u53c2\u8003\u6587\u732e<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"s-block-item s-repeatable-item s-block-sortable-item s-blog-post-section blog-section\">\n<div class=\"container\">\n<div class=\"sixteen columns\">\n<div class=\"s-blog-section-inner\">\n<div class=\"s-component s-text\">\n<div class=\"\">\n<div class=\"s-component-content s-font-body\">\n<p>Igarashi M, Nakagawa-Nagahama Y, Miura M, Kashiwabara K, Yaku K, Sawada M, Sekine R, Fukamizu Y, Sato T, Sakurai T, Sato J, Ino K, Kubota N, Nakagawa T, Kadowaki T, Yamauchi T. Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men. NPJ Aging. 2022 May 1;8(1):5. doi: 10.1038\/s41514-022-00084-z. PMID: 35927255; PMCID: PMC9158788.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"s-block-item s-repeatable-item s-block-sortable-item s-blog-post-section blog-section\">\n<div class=\"container\">\n<div class=\"sixteen columns\">\n<div class=\"s-blog-section-inner\">\n<div class=\"s-component s-text\">\n<div class=\"\">\n<div class=\"s-component-content s-font-body\">\n<p>\u6587\u7ae0\u4f86\u6e90<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"s-block-item s-repeatable-item s-block-sortable-item s-blog-post-section blog-section\">\n<div class=\"container\">\n<div class=\"sixteen columns\">\n<div class=\"s-blog-section-inner\">\n<div class=\"s-component s-text\">\n<div class=\"\">\n<div class=\"s-component-content s-font-body\">\n<p>https:\/\/www.nmn.com\/news\/twelve-weeks-of-nmn-supplementation-more-than-doubles-nad-levels-and-improves-muscle-function-researchers-find<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"pvc_clear\"><\/div>\n<p id=\"pvc_stats_18916\" class=\"pvc_stats all  \" data-element-id=\"18916\" style=\"\"><i class=\"pvc-stats-icon medium\" aria-hidden=\"true\"><svg aria-hidden=\"true\" focusable=\"false\" data-prefix=\"far\" data-icon=\"chart-bar\" role=\"img\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\" class=\"svg-inline--fa fa-chart-bar fa-w-16 fa-2x\"><path fill=\"currentColor\" d=\"M396.8 352h22.4c6.4 0 12.8-6.4 12.8-12.8V108.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v230.4c0 6.4 6.4 12.8 12.8 12.8zm-192 0h22.4c6.4 0 12.8-6.4 12.8-12.8V140.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v198.4c0 6.4 6.4 12.8 12.8 12.8zm96 0h22.4c6.4 0 12.8-6.4 12.8-12.8V204.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v134.4c0 6.4 6.4 12.8 12.8 12.8zM496 400H48V80c0-8.84-7.16-16-16-16H16C7.16 64 0 71.16 0 80v336c0 17.67 14.33 32 32 32h464c8.84 0 16-7.16 16-16v-16c0-8.84-7.16-16-16-16zm-387.2-48h22.4c6.4 0 12.8-6.4 12.8-12.8v-70.4c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v70.4c0 6.4 6.4 12.8 12.8 12.8z\" class=\"\"><\/path><\/svg><\/i> <img loading=\"lazy\" decoding=\"async\" width=\"16\" height=\"16\" alt=\"Loading\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/plugins\/page-views-count\/ajax-loader-2x.gif\" border=0 \/><\/p>\n<div class=\"pvc_clear\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u65e5\u672c\u79d1\u5b66\u5bb6\u8868\u660e\uff0c\u7ed9\u8001\u5e74\u7537\u6027\u670d\u7528 NMN \u53ef\u4f7f\u8840\u6db2\u4e2d\u7684 NAD+ \u6c34\u5e73\u589e\u52a0\u4e00\u500d\u4ee5\u4e0a\uff0c\u5e76\u63d0\u9ad8\u6b65\u884c\u901f\u5ea6\u548c\u63e1\u529b\u3002 \u91cd\u5927\u4eae\u70b9 \u6bcf\u5929\u670d\u7528 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