{"id":18601,"date":"2022-08-01T21:56:23","date_gmt":"2022-08-01T21:56:23","guid":{"rendered":"http:\/\/johnhealth.blog\/ch\/?p=18601"},"modified":"2022-08-01T21:56:23","modified_gmt":"2022-08-01T21:56:23","slug":"%e7%b4%ab%e6%aa%80%e8%8a%aa%e4%b8%8e%e5%a4%a7%e8%84%91%e5%81%a5%e5%ba%b7","status":"publish","type":"post","link":"http:\/\/johnhealth.blog\/ch\/?p=18601","title":{"rendered":"\u7d2b\u6a80\u82aa\u4e0e\u5927\u8111\u5065\u5eb7"},"content":{"rendered":"<p>\u8d8a\u6765\u8d8a\u591a\u7684\u7814\u7a76\u8868\u660e\u996e\u98df\u5728\u5065\u5eb7\u548c\u8870\u8001\u4e2d\u7684\u6709\u76ca\u4f5c\u7528\uff0c\u7279\u522b\u662f\u5177\u6709\u751f\u7269\u6d3b\u6027\u7684\u690d\u7269\u6765\u6e90\u5316\u5408\u7269\u7684\u996e\u98df\u3002\u7d2b\u6a80\u82aa\u56e0\u5176\u5f3a\u5927\u7684\u6297\u6c27\u5316\u3001\u6297\u708e\u548c\u6297\u764c\u4f5c\u7528\u800c\u5907\u53d7\u5173\u6ce8\uff0c\u7d2b\u6a80\u82aa\u5bf9\u5927\u8111\u529f\u80fd\u6709\u76ca\u7684\u8bc1\u636e\u4eca\u5e74\u6765\u4e5f\u9010\u6e10\u88ab\u53d1\u73b0\u3002\u4e0b\u9762\u6211\u4eec\u6df1\u5165\u4e86\u89e3\u7d2b\u6a80\u82aa\u5728\u5927\u8111\u5065\u5eb7\uff0c\u7279\u522b\u662f\u5728\u6297\u6c27\u5316\u548c\u6297\u708e\u4fe1\u53f7\u548c\u6539\u5584\u8ba4\u77e5\u529f\u80fd\u4e0a\u7684\u4f5c\u7528\u3002<\/p>\n<p>\u901a\u5e38\u8840\u8111\u5c4f\u969c\u4f1a\u963b\u6b6298%\u7684\u5c0f\u5206\u5b50\u548c\u6240\u6709\u5927\u5206\u5b50\u5230\u8fbe\u5927\u8111\uff0c\u800c<strong><span style=\"color: #ff6600;\">\u7d2b\u6a80\u82aa\u80fd\u591f\u7a7f\u8fc7\u8840\u8111\u5c4f\u969c\u5e76\u5728\u5927\u8111\u4e2d\u79ef\u7d2f<\/span><\/strong>\u3002Joseph\u7b49\u7814\u7a76\u8005\u53d1\u73b0\u53e3\u670d\u7d2b\u6a80\u82aa\u540e\u80fd\u591f\u5728\u5c0f\u9f20\u8111\u7ec4\u7ec7\u4e2d\u68c0\u6d4b\u5230\u7d2b\u6a80\u82aa\uff0c\u8bf4\u660e\u7d2b\u6a80\u82aa\u80fd\u591f\u8fdb\u5165\u8111\u7ec4\u7ec7\u4e2d\u53d1\u6325\u8c03\u8282\u4f5c\u7528<sup>[1]<\/sup>\u3002<span id=\"more-16189\"><\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-large wp-image-18602\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2022\/08\/WeChat-Image_20220123083505-1024x676.png\" alt=\"\" width=\"900\" height=\"594\" srcset=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2022\/08\/WeChat-Image_20220123083505-1024x676.png 1024w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2022\/08\/WeChat-Image_20220123083505-300x198.png 300w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2022\/08\/WeChat-Image_20220123083505-768x507.png 768w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2022\/08\/WeChat-Image_20220123083505.png 1280w\" sizes=\"auto, (max-width: 900px) 100vw, 900px\" \/><\/p>\n<p>\u8870\u8001\u8fc7\u7a0b\u4e2d\u7684\u6c27\u5316\u635f\u4f24\u548c\u53ca\u5927\u8111\u81ea\u566c\u529f\u80fd\u7684\u4e27\u5931\u4f1a\u5bfc\u81f4\u8ba4\u77e5\u529f\u80fd\u7684\u4e27\u5931\u3002\u4e00\u9879\u5229\u7528\u5c0f\u9f20\u6a21\u578b\u5f00\u5c55\u7684\u7814\u7a76\u53d1\u73b0\uff0c<span style=\"color: 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alt=\"\" width=\"900\" height=\"577\" srcset=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2022\/08\/WeChat-Image_20220123083257-1024x656.jpg 1024w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2022\/08\/WeChat-Image_20220123083257-300x192.jpg 300w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2022\/08\/WeChat-Image_20220123083257-768x492.jpg 768w, http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2022\/08\/WeChat-Image_20220123083257.jpg 1080w\" sizes=\"auto, (max-width: 900px) 100vw, 900px\" \/><\/section>\n<p>\u53e6\u4e00\u9879\u7814\u7a76\u8fdb\u4e00\u6b65\u8bc4\u4ef7\u4e86\u7d2b\u6a80\u82aa\u5bf9\u963f\u5c14\u5179\u6d77\u9ed8\u75c7\u7684\u6539\u5584\u6548\u679c\u3002<span style=\"color: #ff6600;\"><strong>\u996e\u98df\u4e2d\u6dfb\u52a0\u7d2b\u6a80\u82aa\u4e24\u4e2a\u6708\u540e\uff0c\u5c0f\u9f20\u7684\u7ec6\u80de\u5e94\u6fc0\u3001\u708e\u75c7\u548c\u963f\u5c14\u5179\u6d77\u9ed8\u75c7\u75c5\u7406\u6807\u5fd7\u7269\u5747\u51cf\u5c11\uff0c\u8ba4\u77e5\u529f\u80fd\u5f97\u5230\u6539\u5584<\/strong><\/span>\u3002\u5e76\u4e14\u540c\u6837\u6761\u4ef6\u4e0b\u767d\u85dc\u82a6\u9187\u672a\u53d1\u6325\u6548\u679c\uff0c\u8868\u660e\u7d2b\u6a80\u82aa\u7531\u4e8e\u5177\u6709\u9ad8\u4eb2\u8102\u6027\u548c\u9ad8\u6e17\u900f\u6027\uff0c\u6bd4\u767d\u85dc\u82a6\u9187\u66f4\u80fd\u8c03\u8282\u5927\u8111\u529f\u80fd<sup>[4]<\/sup>\u3002<\/p>\n<p>\u6700\u65b0\u7684\u7814\u7a76\u53d1\u73b0\u7d2b\u6a80\u82aa\u5bf9\u4e8e\u60c5\u7eea\u8c03\u8282\u548c\u7761\u7720\u8c03\u8282\u4e5f\u6709\u4e00\u5b9a\u7684\u4f5c\u7528\u3002Yang\u7b49\u4eba\u7684\u7814\u7a76\u53d1\u73b0<span style=\"color: #ff6600;\"><strong>\u53e3\u670d\u7d2b\u6a80\u82aa\u80fd\u591f\u4fc3\u8fdb\u5927\u9f20\u5927\u8111\u795e\u7ecf\u5e72\u7ec6\u80de\u7684\u589e\u6b96\uff0c\u51cf\u8f7b\u6a21\u578b\u5927\u9f20\u7684\u6291\u90c1\u6837\u75c7\u72b6\uff0c\u6539\u5584\u5927\u9f20\u884c\u4e3a\u80fd\u529b<\/strong><\/span><sup>[<\/sup><sup>5<\/sup><sup>]<\/sup>\u3002<\/p>\n<p>\u53e6\u5916\uff0c\u6211\u4eec\u4eba\u4f53\u6709\u4e00\u4e2a24\u5c0f\u65f6\u7684\u663c\u591c\u8282\u5f8b\u7cfb\u7edf\uff0c\u63a7\u5236\u751f\u7269\u4f53\u7684\u5185\u6e90\u6027\u65f6\u95f4\uff0c\u4e0e\u7761\u7720\u76f8\u4e92\u4f5c\u7528\u8c03\u8282\u4eba\u4f53\u751f\u7406\u548c\u884c\u4e3a\u6d3b\u52a8\u3002\u79d1\u5b66\u5bb6\u4f7f\u7528\u4e00\u79cd\u201c\u7761\u7720\u9650\u5236\uff08Sleep Restriction\uff0cSR\u6a21\u578b\uff09\u5c0f\u9f20\u6a21\u578b\u201d\uff0cSR\u6a21\u578b\u6a21\u62df\u4e86\u4eba\u7c7b\u71ac\u591c\uff0c\u7ed3\u679c\u53d1\u73b0<span style=\"color: #ff6600;\"><strong>\u5c0f\u9f20\u6444\u5165\u7d2b\u6a80\u82aa\u540e\u98df\u6b32\u548c\u4f53\u91cd\u5747\u8868\u73b0\u6b63\u5e38\uff0c\u8fd0\u52a8\u8010\u529b\u663e\u8457\u9ad8\u4e8e\u4e0d\u6444\u5165\u7d2b\u6a80\u82aa\u7684\u5c0f\u9f20<\/strong><\/span>\uff0c\u5e76\u4e14\u4e0d\u6613\u75b2\u52b3\u3002\u7d2b\u6a80\u82aa\u901a\u8fc7\u8c03\u8282AMPK\/SIRT1\/PGC-1\u03b1\u901a\u8def\u6539\u5584\u5c0f\u9f20\u7684\u663c\u591c\u8282\u5f8b\u7cfb\u7edf\u7684\u5931\u8c03\u4ee5\u53ca\u7761\u7720\u72b6\u51b5<sup>[<\/sup><sup>6<\/sup><sup>]<\/sup>\u3002<\/p>\n<section data-mpa-template=\"t\">\n<section data-mid=\"\">\n<section data-mid=\"\">\n<section data-mid=\"\">\n<section data-mid=\"\">\n<p data-mid=\"\">\u53c2\u8003\u6587\u732e\uff1a<\/p>\n<p data-mid=\"\">[1] Joseph J A, Fisher D R, Cheng V, et al. Cellular and Behavioral Effects of Stilbene Resveratrol Analogues: Implications for Reducing the Deleterious Effects of Aging. Journal of Agricultural and Food Chemistry, 2008, 56(22): 10544-10551.<\/p>\n<p data-mid=\"\">[2] Liu H, Wu X, Luo J, et al. Pterostilbene Attenuates Astrocytic Inflammation and Neuronal Oxidative Injury After Ischemia-Reperfusion by Inhibiting NF-\u03baB Phosphorylation. Frontiers in Immunology, 2019, 10: 2408.<\/p>\n<p data-mid=\"\">[3] Hou Y, Xie G, Miao F, et al. Pterostilbene attenuates lipopolysaccharide-induced learning and memory impairment possibly via inhibiting microglia activation and protecting neuronal injury in mice. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2014, 54: 92-102.<\/p>\n<p data-mid=\"\">[4] Chang J, Rimando A, Pallas M, et al. Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer\u2019s disease. Neurobiology Of Aging, 2012, 33(9): 2062-2071.<\/p>\n<p data-mid=\"\">[5] Yang L, Ran Y, Quan Z, et al. Pterostilbene, an active component of the dragon\u2019s blood extract, acts as an antidepressant in adult rats. Psychopharmacology, 2019, 236(4): 1323-1333.<\/p>\n<p data-mid=\"\">[6] Liu Y, Lang H, Zhou M, et al. The Preventive Effects of Pterostilbene on the Exercise Intolerance and Circadian Misalignment of Mice Subjected to Sleep Restriction. Molecular Nutrition &amp; Food Research, 2020, 64(11): e1900991.<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<div class=\"pvc_clear\"><\/div>\n<p id=\"pvc_stats_18601\" class=\"pvc_stats all  \" data-element-id=\"18601\" style=\"\"><i class=\"pvc-stats-icon medium\" aria-hidden=\"true\"><svg aria-hidden=\"true\" focusable=\"false\" data-prefix=\"far\" data-icon=\"chart-bar\" role=\"img\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\" class=\"svg-inline--fa fa-chart-bar fa-w-16 fa-2x\"><path fill=\"currentColor\" d=\"M396.8 352h22.4c6.4 0 12.8-6.4 12.8-12.8V108.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v230.4c0 6.4 6.4 12.8 12.8 12.8zm-192 0h22.4c6.4 0 12.8-6.4 12.8-12.8V140.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v198.4c0 6.4 6.4 12.8 12.8 12.8zm96 0h22.4c6.4 0 12.8-6.4 12.8-12.8V204.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v134.4c0 6.4 6.4 12.8 12.8 12.8zM496 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Restriction\uff0cSR\u6a21\u578b\uff09\u5c0f\u9f20\u6a21\u578b\u201d\uff0cSR\u6a21\u578b\u6a21\u62df\u4e86\u4eba\u7c7b\u71ac\u591c\uff0c\u7ed3\u679c\u53d1\u73b0\u5c0f\u9f20\u6444\u5165\u7d2b\u6a80\u82aa\u540e\u98df\u6b32\u548c\u4f53\u91cd\u5747\u8868\u73b0\u6b63\u5e38\uff0c\u8fd0\u52a8\u8010\u529b\u663e\u8457\u9ad8\u4e8e\u4e0d\u6444\u5165\u7d2b\u6a80\u82aa\u7684\u5c0f\u9f20\uff0c\u5e76\u4e14\u4e0d\u6613\u75b2\u52b3\u3002\u7d2b\u6a80\u82aa\u901a\u8fc7\u8c03\u8282AMPK\/SIRT1\/PGC-1\u03b1\u901a\u8def\u6539\u5584\u5c0f\u9f20\u7684\u663c\u591c\u8282\u5f8b\u7cfb\u7edf\u7684\u5931\u8c03\u4ee5\u53ca\u7761\u7720\u72b6\u51b5[6]\u3002 \u53c2\u8003\u6587\u732e\uff1a [1] Joseph J A, Fisher D R, Cheng V, et al. Cellular and Behavioral Effects of Stilbene Resveratrol Analogues: Implications for Reducing the Deleterious Effects of Aging. Journal of Agricultural and Food Chemistry, 2008, 56(22): 10544-10551. [2] Liu H, Wu X, Luo J, et al. 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