{"id":18594,"date":"2022-08-01T21:40:52","date_gmt":"2022-08-01T21:40:52","guid":{"rendered":"http:\/\/johnhealth.blog\/ch\/?p=18594"},"modified":"2022-08-01T21:44:03","modified_gmt":"2022-08-01T21:44:03","slug":"%e7%ac%ac%e4%ba%8c%e4%bb%a3%e7%99%bd%e8%97%9c%e8%8a%a6%e9%86%87-%e7%b4%ab%e6%aa%80%e8%8a%aa","status":"publish","type":"post","link":"http:\/\/johnhealth.blog\/ch\/?p=18594","title":{"rendered":"\u7b2c\u4e8c\u4ee3\u767d\u85dc\u82a6\u9187 \u2013 \u7d2b\u6a80\u82aa"},"content":{"rendered":"<p>\u7d2b\u6a80\u82aa \uff0c\u88ab\u79f0\u4e3a\u201c\u7b2c\u4e8c\u4ee3\u767d\u85dc\u82a6\u9187\u201d\uff0c\u4f5c\u4e3a\u53cd\u5f0f\u4e8c\u82ef\u4e59\u70ef\u7c7b\u5316\u5408\u7269\uff0c\u662f\u767d\u85dc\u82a6\u9187\u7684\u7532\u57fa\u5316\u884d\u751f\u7269\u3002\u7814\u7a76\u8868\u660e,\u7d2b\u6a80\u82aa\u5177\u6709\u767d\u85dc\u82a6\u9187\u7684\u591a\u79cd\u751f\u7269\u6d3b\u6027,\u5982\u7f13\u89e3\u708e\u6027\u53cd\u5e94\u3001\u6297\u6c27\u5316\u3001\u6297\u8870\u8001\u3001\u4ee5\u53ca\u5fc3\u8840\u7ba1\u4fdd\u62a4\u7b49\u4f5c\u7528\u3002<img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-18595 alignright\" src=\"http:\/\/johnhealth.blog\/ch\/wp-content\/uploads\/2022\/08\/\u56fe\u7247-300x217-1.png\" alt=\"\" width=\"300\" height=\"217\" \/><\/p>\n<p>\u4e0e\u767d\u85dc\u82a6\u9187\u76f8\u6bd4\uff0c<strong><span style=\"color: #ff0000;\">\u7d2b\u6a80\u82aa\u5177\u6709\u66f4\u597d\u7684\u751f\u7269\u5229\u7528\u5ea6\u3001\u4ee3\u8c22\u7a33\u5b9a\u6027\u3001\u6297\u6c27\u5316\u6d3b\u6027\u3001\u548c\u819c\u901a\u900f\u6027<\/span><\/strong>\u3002<\/p>\n<h3><span style=\"color: #ff6600;\">\u652f\u6301\u5fc3\u8840\u7ba1\u5065\u5eb7<\/span><\/h3>\n<p><!--more--><\/p>\n<p style=\"padding-left: 40px;\">\u901a\u8fc7\u8c03\u8282\u8840\u7ba1\u5e73\u6ed1\u808c\u7ec6\u80de\u3001\u8840\u7ba1\u5185\u76ae\u7ec6\u80de\u548c\u6297\u6c27\u5316\u9176SOD\u964d\u4f4e\u52a8\u8109\u7ca5\u6837\u786c\u5316\u98ce\u9669\u3002<br \/>\n(Park ES, et al., 2010)<\/p>\n<h3><span style=\"color: #ff6600;\">\u652f\u6301\u80c3\u80a0\u9053\u5065\u5eb7<\/span><\/h3>\n<p style=\"padding-left: 40px;\">\u7d2b\u6a80\u82aa\u5bf9\u98df\u9053\u3001\u80c3\u3001\u7ed3\u80a0\u5185\u7684\u6709\u5bb3\u7ec6\u80de\u5177\u6709\u4e00\u5b9a\u6291\u5236\u751f\u957f\u7684\u4f5c\u7528\uff0c\u51cf\u5c11\u80c3\u80a0\u9053\u4e0d\u826f\u708e\u6027\u53cd\u5e94\u3002<br \/>\n(Wang YP, et al., 2010)<\/p>\n<h3><span style=\"color: #ff6600;\">\u6539\u5584\u809d\u810f\u5065\u5eb7<\/span><\/h3>\n<p style=\"padding-left: 40px;\">\u7d2b\u6a80\u82aa\u7b49\u84dd\u8393\u63d0\u53d6\u7269\u53ef\u4ee5\u589e\u52a0Nrf2\u901a\u8def\u548c\u6297\u6c27\u5316\u9176\u7684\u8868\u8fbe\u3002\u4e00\u9879\u5b9e\u9a8c\u8868\u660e\uff0c\u670d\u7528\u4e86\u7d2b\u6a80\u82aa\u7684\u5b9e\u9a8c\u5bf9\u8c61\u4f53\u5185\u6025\u6027\u809d\u635f\u4f24\u7684\u6807\u5fd7\u7269\u660e\u663e\u964d\u4f4e\u3002<br \/>\n(Pari L, Satheesh MA., 2006)<\/p>\n<h3><span style=\"color: #ff6600;\">\u6539\u5584\u7cd6\u7c7b\u4ee3\u8c22<\/span><\/h3>\n<p style=\"padding-left: 40px;\">\u5728\u5b9e\u9a8c\u5bf9\u8c61\u6444\u5165\u516d\u5468\u7684\u7d2b\u6a80\u82aa\u540e\uff0c\u4f53\u5185\u7684\u8840\u7cd6\u6c34\u5e73\u663e\u8457\u964d\u4f4e\uff0c\u8840\u6d46\u80f0\u5c9b\u7d20\u6c34\u5e73\u663e\u8457\u4e0a\u5347\u3002\u7d2b\u6a80\u82aa\u540c\u65f6\u53ef\u4ee5\u589e\u52a0\u7cd6\u9175\u89e3\u7684\u8868\u8fbe\uff0c\u4fc3\u8fdb\u7cd6\u7c7b\u4ee3\u8c22\u3002<br \/>\n(Satheesh MA, Pari L., 2006)<\/p>\n<h3><span style=\"color: #ff6600;\">\u6539\u5584\u8102\u80aa\u4ee3\u8c22<\/span><\/h3>\n<p style=\"padding-left: 40px;\">\u57283T3-L1\u524d\u8102\u80aa\u7ec6\u80de\u4e2d\uff0c\u7d2b\u6a80\u82aa\u53ef\u4ee5\u51cf\u5c11\u8102\u80aa\u7ec6\u80de\u7fa4\u751f\u957f\uff0c\u51cf\u5c11\u7518\u6cb9\u4e09\u916f\u5728\u4f53\u5185\u7684\u7d2f\u79ef\u3002<br \/>\n\u4e00\u9879\u5b9e\u9a8c\u7814\u7a76\u8868\u660e\uff0c\u7d2b\u6a80\u82aa\u53ef\u4ee5\u964d\u4f4e\u5c0f\u9f20\u4f53\u5185\u7684\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\uff08LDL\uff09\u3002<br \/>\n(Rimando AM et al., 2005)<\/p>\n<h3><span style=\"color: #ff6600;\">\u5ef6\u7f13\u8111\u90e8\u8870\u8001<\/span><\/h3>\n<p style=\"padding-left: 40px;\">\u7d2b\u6a80\u82aa\u53ef\u4ee5\u51cf\u7f13\u8bb0\u5fc6\u53ca\u7531\u708e\u6027\u53cd\u5e94\u5f15\u8d77\u7684\u8111\u90e8\u8870\u9000\uff0c\u7f13\u89e3\u5927\u8111\u8870\u8001\u3002<br \/>\n\uff08Lange, KW, Li, SM., 2017\uff09<\/p>\n<div class=\"pvc_clear\"><\/div>\n<p id=\"pvc_stats_18594\" class=\"pvc_stats all  \" data-element-id=\"18594\" style=\"\"><i class=\"pvc-stats-icon medium\" aria-hidden=\"true\"><svg aria-hidden=\"true\" focusable=\"false\" data-prefix=\"far\" data-icon=\"chart-bar\" role=\"img\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\" class=\"svg-inline--fa fa-chart-bar fa-w-16 fa-2x\"><path fill=\"currentColor\" d=\"M396.8 352h22.4c6.4 0 12.8-6.4 12.8-12.8V108.8c0-6.4-6.4-12.8-12.8-12.8h-22.4c-6.4 0-12.8 6.4-12.8 12.8v230.4c0 6.4 6.4 12.8 12.8 12.8zm-192 0h22.4c6.4 0 12.8-6.4 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